Citations with the tag: RATS as laboratory animals
Results 1 - 50
- Disposition of Orally Administered 2,2-Bis(4-hydroxyphenyl)propane (Bisphenol A) in Pregnant Rats and the Placental Transfer to Fetuses.
Takahashi, Osamu // Environmental Health Perspectives; Oct2000, Vol. 108 Issue 10, p931Examines the disposition of orally administered 2,2-Bis(4-hydroxyphenyl)propane (Bisphenol A ) in pregnant female rats in Japan. Characteristics of the absorption and distribution of bisphenol A (BPA) in maternal organs and fetuses; Contributions of BPA on toxicity in male reproductive organs;...
- PROFESSOR HAS TWO BRAINS.
Takahashi, Osamu // Current Science; 1/21/2005, Vol. 90 Issue 10, p13Presents information related to an experiment performed to develop brain from rat brain cells.
- Cholecystokinin-induced anxiety in rats: Relevance of pre-experimental stress and seasonal variations.
Koks, Sulev; Mainnisto, Pekka T.; Bourin, Michel; Shlik, Jakov; Vasar, Veiko; Vasar, Eero // Journal of Psychiatry & Neuroscience; Jan2000, Vol. 25 Issue 1, p33Examines the influence of pre-experimental stress on the axiogenic-like action of cholecystokinin (CCK) receptor agonist caerulein in laboratory rats. Role of CCK in differences in the anxiety levels of rats in summer and winter; Interventions made in the study; Caerulein's impact on rats'...
- Effect of Phosgene on Rat Lungs after Single High-Level Exposure.
Frosolono, M.F.; Pawlowski, R. // Archives of Environmental Health; Nov/Dec77, Vol. 32 Issue 6Part I. Examines the effect of Phosgene exposure on rat lungs. Level of phosgene concentrations administered to rats; Increase in the serum levels and water content in the lungs of rats; Role of inhibited enzyme activity in the lungs on phosgene damage.
- Effect of Phosgene on Rat Lungs after Single High-Level Exposure.
Pawlowski, R.; Frosolono, M.F. // Archives of Environmental Health; Nov/Dec77, Vol. 32 Issue 6Part II. Examines the effects of Phosgene exposure on rat lungs. Disease caused by phosgene exposure; Detection of phosgene damage in the bronchiolar epithelium; Development of a septal edema following exposure; Condition of interstitial cells following interstitial edema.
- Life as a laboratory rat--through the eyes of Traum.
Blackwolf, Rebekah // Animals Today; Feb-Apr98, Vol. 6 Issue 1, p21Delineates the fear and anguish of a laboratory rat. Usefulness of rats in scientific breakthroughs; Irony between human improvement and animal destruction; Question on the need for frequent laboratory research.
- Production of knockout rats using ENU mutagenesis and a yeast-based screening assay.
Zan, Yunhong; Haag, Jill D; Chen, Kai-Shun; Shepel, Laurie A; Wigington, Don; Wang, Yu-Rong; Hu, Rong; Lopez-Guajardo, Christine C; Brose, Heidi L; Porter, Katherine I; Leonard, Rachel A; Hitt, Andrew A; Schommer, Stacy L; Elegbede, Anu F; Gould, Michael N // Nature Biotechnology; Jun2003, Vol. 21 Issue 6, p645The rat is a widely used model in biomedical research and is often the preferred rodent model in many areas of physiological and pathobiological research. Although many genetic tools are available for the rat, methods to produce gene-disrupted knockout rats are greatly needed. In this study, we...
- Maternal care, hippocampal synaptogenesis and cognitive development in rats.
Liu, Dong; Diorio, Josie; Day, Jamie C.; Francis, Darlene D.; Meaney, Michael J. // Nature Neuroscience; Aug2000, Vol. 3 Issue 8, p799We report that variations in maternal care in the rat promote hippocampal synaptogenesis and spatial learning and memory through systems known to mediate experience-dependent neural development. Thus, the offspring of mothers that show high levels of pup licking and grooming and arched-back...
- VOLUMINOUS SUCROSE CONSUMPTION IN FEMALE RATS: INCREASED 'NIPPINESS' DURING PERIODS OF SUCROSE REMOVAL AND POSSIBLE OESTRUS PERIODICITY.
Galic, M.A.; Persinger, M.A. // Psychological Reports; Feb2002, Vol. 90 Issue 1, p58Examines the sucrose consumption in female rats. Impact of sucrose on rat chow rate; Reaction of rats in sucrose removal; Clinical implications of the presence of robust phenomenon during sucrose consumption.
- The endocannabinoid system: a modulator of brain-behavioral processes.
Deadwyler, Sam // Psychopharmacology; Jul2008, Vol. 198 Issue 4, p447The article presents an introduction to the issue, discussing such articles as "Rimonabant blocks the expression but not the development of locomotor sensitization to nicotine in rats," by John E. Kelsey and Siena Calabro, and "Endocannabinoid modulation of male rat sexual behavior," by Boris B....
- Environmental stimuli promote the acquisition of nicotine self-administration in rats.
Caggiula, Anthony R.; Donny, Eric C.; White, Anthony R.; Chaudhri, Nadia; Booth, Sheri; Gharib, Maysa A.; Hoffman, Alycia; Perkins, Kenneth A.; Sved, Alan F. // Psychopharmacology; 2002, Vol. 163 Issue 2, p230Rationale: Environmental stimuli associated with drugs of abuse are believed to play a major role in the motivation to take drugs, drug dependence, and relapse. Previous work from this laboratory demonstrated that the response-contingent presentation of drug-related, visual cues was at least as...
- Hat Turns Rats Into Robots.
Caggiula, Anthony R.; Donny, Eric C.; White, Anthony R.; Chaudhri, Nadia; Booth, Sheri; Gharib, Maysa A.; Hoffman, Alycia; Perkins, Kenneth A.; Sved, Alan F. // Popular Mechanics; Aug2002, Vol. 179 Issue 8, p26Reports on an experiment in which electrodes were attached to a rat's brain that receive computer commands aimed at using rats for search and rescue operations.
- Reproductive biology: Puberty controlled by DNA changes.
Caggiula, Anthony R.; Donny, Eric C.; White, Anthony R.; Chaudhri, Nadia; Booth, Sheri; Gharib, Maysa A.; Hoffman, Alycia; Perkins, Kenneth A.; Sved, Alan F. // Nature; 2/7/2013, Vol. 494 Issue 7435, p9The article presents a study by researchers Alejandro Lomniczi and Sergio Ojeda at Oregon Health & Science University in Portland and their colleagues, which found that the declining levels of the genesilencing molecule EED may control the puberty process in rats.
- Identification of a Novel Splice Variant of C3G Which Shows Tissue-Specific Expression.
Shivakrupa; Singh, Rita; Swarup, Ghanshyam // DNA & Cell Biology; Sep99, Vol. 18 Issue 9, p701C3G is a guanine nucleotide-releasing protein that binds to the Src homology 3 (SH3) domain of the adapter protein Crk. In this study, we isolated cDNAs coding for rat C3G. Northern blot analysis of RNA from various rat tissues and cell lines showed a major transcript of about 7 kb which was...
- Introduction to Article by Sistare et al.
Morton, Daniel; Alden, Carl L. // Toxicologic Pathology; Jun2011, Vol. 39 Issue 4, p715An introduction to the article, "A Critical Review of the Effectiveness of Rodent Pharmaceutical Carcinogenesis Testing in Predicting for Human Risk," by F. Sistare et al, published within the issue is presented.
- Effect of genestein on the prostate gland.
Morton, Daniel; Alden, Carl L. // Life Extension; Jan2003, Vol. 9 Issue 1, p78Investigates the effect of dietary genistein in the activity of the sex steroid cell receptor in the prostate gland. Inhibition of prostate tumor development in rats; Reduction of the activity of the male and female steroid receptors; Factors responsible for the lower incidence of prostate cancer.
- POLITICAL MISUSE OF SCIENCE.
Stephen, Jr., William F. // BioScience; Jul1978, Vol. 28 Issue 7, p424A letter to the editor is presented in response to an article related to rats and research by Jeremy Stone in the February 1978 issue.
- Developmental stage-specific involvement of angiotensin in murine nephrogenesis.
Kakinuma, Y.; Sugiyama, F.; Taniguchi, K.; Horiguchi, H.; Ogata, T.; Murakami, K.; Yagami, K.; Fukamizu, A. // Pediatric Nephrology; 1999, Vol. 13 Issue 9, p792Angiotensinogen-deleted mice (Agt-KO) show phenotypes of hypotension and renal atrophy. To investigate whether an alternative pathway other than angiotensin II (AII), i.e., processed angiotensin fragments, may play a biological role in nephrogenesis, we analyzed a congenic line of Agt-KO fetuses...
- Magnitude of Antihypertensive Effect Related to Degree of Renoprotection.
Kakinuma, Y.; Sugiyama, F.; Taniguchi, K.; Horiguchi, H.; Ogata, T.; Murakami, K.; Yagami, K.; Fukamizu, A. // Kidney; Jul/Aug98, Vol. 7 Issue 4, p148Presents a summary of the article 'Effects of Combination Therapy With Enalapril and Losartan on the Rate of Progression of Renal Injury in Rats With 5/6 Renal Mass Ablation,' by M. Ots, J.L. Troy et al published in 'Journal of American Society of Nephrology' periodical.
- AQP4 may play a role in adapting cerebral tissue to hyponatremia.
Kakinuma, Y.; Sugiyama, F.; Taniguchi, K.; Horiguchi, H.; Ogata, T.; Murakami, K.; Yagami, K.; Fukamizu, A. // Kidney; Jan/Feb2001, Vol. 10 Issue 1, p8Presents an abstract of the study 'Increased Aquaporin-4 Immunoreactivity in Rat Brain in Response to Systemic Hyponatremia,' by Z. Vajda, D. Promeneur, T. D � czi et al.
- Effects of high doses of naltrexone on running and responding for the opportunity to run in rats: A test of the opiate hypothesis.
BELKE, T. W.; DUNLOP, L. // Psychological Record; Fall98, Vol. 48 Issue 4, p675Presents information on a study which evaluates the effects of high doses of naltrexone on running and responding for the opportunity to run in rats. Method; Results and discussion.
- Would you believe...a rat that wires schools?
BELKE, T. W.; DUNLOP, L. // Technology & Learning; Jan98, Vol. 18 Issue 5, p28Discusses the incredulity of a laboratory rat being used to install a wiring system to link a school to the Internet. Details on the effort launched by Dr. Judy Reavis; How Reavis was able to accomplish her task through the assistance of the rat; Information on Net Day; Details on the popularity...
- Lead.
Mouw, David; Kalitis, Kenneth; Anver, Miriam; Schwartz, Joyce; Constan, Anna; Hartung, Rolf; Cohen, Bennet; Ringler, Dan // Archives of Environmental Health; Jun75, Vol. 30 Issue 6, p276Examines the degree of lead toxicity in urban and rural rats. Presence of higher lead concentrations in urban rats than in rural rats; Dissociation between tissue lead concentrations and total body weights; Manifestation of eosinophilic intranuclear inclusion bodies in proximal tubular-epithelium.
- Blood digestion-induced splanchnic hyperemia and portal blood flow in portal hypertensive rats and the role of octreotide.
Kotzampassi, Katerina; Eleftheriadis, Efthimios // Journal of Gastroenterology; 1998, Vol. 33 Issue 5, p678Abstract: We aimed to investigate whether the presence of blood within the intestinal lumen after variceal bleeding would lead to reactive intestinal hyperemia, which in turn could result in the worsening of portal hemodynamics, and thus bleeding recurrence. Two models of portal hypertensive...
- Determination of Aroclor 1248 in Rat Plasma and Liver Matrices.
Loconto, Paul R. // LC-GC North America; Nov2002, Vol. 20 Issue 11, p1062Focuses on the determination of Aroclor 1248 in rat plasma and liver matrices. Recovery and quantification considerations; Use of probe sonification coupled with reversed-phase solid-phase extraction; Application of a statistical evaluation of the interpolated values from a least-squares...
- Mice and monoclonal antibody production.
Edwards, Keith // Animals Today; Aug-Oct97, Vol. 5 Issue 3, p15Discusses issues related to the use of rats in the production of monoclonal antibodies (mAbs) in Australia. Uses of mAbs; Suffering associated with ascites and monoclonal antibody production in animals; Development of a gas-permeable tissue culture bag by the Alternatives Research and...
- Can Airborne Odors Attract Males?
Edwards, Keith // USA Today Magazine; Jun1998 Science, Vol. 126 Issue 2637, p1Presents a study on pheromone or an airborne social odor secreted by female rats that acts as an aphrodisiac for male rats. Findings of the study.
- Rats lose weight on the G-plan diet.
Epstein, Helen // New Scientist; 6/3/95, Vol. 146 Issue 1980, p10Reports on research work showing that gravity may help rats lose weight as long as they remained in their new environment. Effect of increases in gravity on bone growth; Description of experiment conducted by researchers; Speculations on the reasons behind the weight loss of rats.
- Cancer specialists join the rat race.
Cohen, Philip // New Scientist; 11/30/96, Vol. 152 Issue 2058, p7Reports on the use of a rodents in an international research effort to test carcinogenic agents. Methods used in testing carcinogens; Requirements of the tests.
- The good life is killing America's fat rats.
Holmes, Bob // New Scientist; 12/9/95, Vol. 148 Issue 2007, p10Reports that overeating is making laboratory rats in the United States unreliable testing animals. Death of rats before the end of the testing period; Weight loss due to experimental substances as sometimes beneficial for rats; Need for a controlled and standardized diet.
- Glycogen Storage in Fetuses of Trained Pregnant Rats.
Houghton, Pamela E.; Mottola, Michelle F.; Mezzapelli, Jamie; Vandermolen, Richard; Christopher, Paul D. // Canadian Journal of Applied Physiology; Aug97, Vol. 22 Issue 4, p384Examines the influence of moderate pre-pregnancy exercise program on glycogen concentration and glycogen distribution of placenta and fetus in pregnant rats. Importance of fetal blood glucose for fetal growth and development; Sources of fetal blood glucose; Factors influencing the fetal growth...
- DHEA.
Houghton, Pamela E.; Mottola, Michelle F.; Mezzapelli, Jamie; Vandermolen, Richard; Christopher, Paul D. // Life Extension; Jun2002, Vol. 8 Issue 6, p79Presents several abstracts on dehydroepiandrosterone. 'Oxidative Derangements in Rat Synaptosomes Induced by Hyperglycaemia: Restorative Effect of Dehydroepiandrosterone Treatment'; 'Dehydroepiandrosterone Prevents Oxidative Injury Induced by Transient Ischemia/Reperfusion in the Brain of...
- POLITICAL MISUSE OF SCIENCE.
Stephen, Jr., William F. // BioScience; Jul1978, Vol. 28 Issue 7, p424A letter to the editor is presented in response to an article related to rats and research by Jeremy Stone in the February 1978 issue.
- Abstracts--sometimes useful, sometimes dangerous.
Kanca, John // Quintessence International; Jul1996, Vol. 27 Issue 7, p445A letter to the editor is presented in response to the editorial "Abstracts--sometimes useful, sometimes dangerous in the 1996;27 issue.
- Abstracts--sometimes useful, sometimes dangerous.
Kanca, John // Quintessence International; Jul1996, Vol. 27 Issue 7, p445A response by the editor to a letter to the editor about his editorial "Abstracts--sometimes useful, sometimes dangerous in a 1996 issue is presented.
- Erratum to: Path-finding in real and simulated rats: assessing the influence of path characteristics on navigation learning.
Tamosiunaite, Minija; Ainge, James; Kulvicius, Tomas; Porr, Bernd; Dudchenko, Paul; W�rg�tter, Florentin // Journal of Computational Neuroscience; Jun2010, Vol. 28 Issue 3, p619A correction to the article "Path-Finding in Real and Simulated Rats: Assessing the Influence of Path Characteristics on Navigation Learning" is presented.
- Drinking Like a Rat.
Tamosiunaite, Minija; Ainge, James; Kulvicius, Tomas; Porr, Bernd; Dudchenko, Paul; W�rg�tter, Florentin // Current Health 2; Feb2009, Vol. 35 Issue 6, p4The article offers information on the study conducted by the scientists at Duke University in Durham, North Carolina identifying the reason of the abuse of alcohol using adolescent rats.
- RAT HEART 'LIVES' AGAIN.
Tamosiunaite, Minija; Ainge, James; Kulvicius, Tomas; Porr, Bernd; Dudchenko, Paul; W�rg�tter, Florentin // New Scientist; 1/19/2008, Vol. 197 Issue 2639, p21The article reports on research in which researchers removed the cells from a rat heart, then reconstituted it using fetal rat cells and the remaining extracellular structure.
- Because it's there.
Tamosiunaite, Minija; Ainge, James; Kulvicius, Tomas; Porr, Bernd; Dudchenko, Paul; W�rg�tter, Florentin // New Scientist; 5/4/2002, Vol. 174 Issue 2341, p5Reports the transformation of living rats into radio-controlled machines in the U.S. Degree of control of the machines; Levels of animal manipulation; Purpose of the experiment.
- Just a sniff can stop strokes.
Coghlan, Andy // New Scientist; 9/14/2002, Vol. 175 Issue 2360, p20Focuses on the effectiveness of a nasal spray in protecting individuals against stroke. Examination of the immune system of rats after administering a nasal spray; Types of stroke; Inclusion of the protein, E-selectin into the ingredients of the vaccine.
- Early experience with a new technique and technology designed for the study of pulsatile cardiopulmonary bypass in the rat.
Gourlay, T; Ballaux, PK; Draper, ERC; Taylor, KM // Perfusion; May2002, Vol. 17 Issue 3, p191The benefits of pulsatile flow during the period of cardiopulmonary bypass (CPB) applied during open-heart surgery remains controversial. We have developed a rodent (rat) model of CBP that has been designed to functionally mimic the clinical setting, principally, but not solely, for the study of...
- Who Moved My Cheese!?
Gourlay, T; Ballaux, PK; Draper, ERC; Taylor, KM // Science Teacher; Dec2003, Vol. 70 Issue 9, p18Reports that researchers at Cold Spring Harbor Laboratory have found that rats can tell two very similar odors apart with just one sniff. Measurement of the speed of smell of rats; Examination of the participation of rats systems of neurons in the creation of perception, awareness and behavior.
- Competition among spatial cues in a naturalistic food-carrying task.
Gibson, Brett M.; Shettleworth, Sara J. // Learning & Behavior; May2003, Vol. 31 Issue 2, p143Rats collected nuts from a container in a large arena in four experiments testing how learning about a beacon or cue at a goal interacts with learning about other spatial cues (place learning). Place learning was quick, with little evidence of competition from the beacon (Experiments 1 and 2)....
- Neuroscience: Rats on the wagon.
Gibson, Brett M.; Shettleworth, Sara J. // Nature; 3/18/2010, Vol. 464 Issue 7287, p328An abstract of the article regarding the research on increased brain activity to rats which were given alcohol for several weeks is presented.
- Develpoment of a Rat Model of Lumbar Facet Joint Inflammation.
Yashpal, Karin; Poon, Sally; Vernon, Howard; Henry, James // Journal of Chiropractic Education; Spring2009, Vol. 23 Issue 1, p101An abstract of the research paper "Development of a Rat Model of Lumbar Facet Joint Inflammation," by Karin Yashpal, Sally Poon, Howard Vernon and James Henry is presented.
- Exercise training effects on vascular reactivity and metabolic parameters of high caloric-fed Wistar rats.
Zanesco, Angelina; De Moraes, Camila; Davel, A. P.; Rossoni, L. V.; De Nucci, Gilberto; Antunes, Edson // BMC Pharmacology; 2007 Supplement 1, Vol. 7, pP67An abstract of the paper "Exercise Training Effects on Vascular Reactivity and Metabolic Parameters of High Caloric-fed Wistar Rats," by Angelina Zanesco, Camila De Moraes, and colleagues is presented.
- Riociguat prevents fibrotic tissue remodelling and improves survival in salt-sensitive Dahl rats.
Geschka, Sandra; Kretschmer, Axel; Sharkovska, Yuliya; Evgenov, Oleg V.; Hucke, Andreas; Lawrenz, Bettina; Hocher, Berthold; Stasch, Johannes-Peter // BMC Pharmacology; 2011 Supplement 1, Vol. 11 Issue Suppl 1, p1An abstract of the article "Riociguat prevents fibrotic tissue remodelling and improves survival in salt-sensitive Dahl rats," by Sandra Geschka and colleagues is presented.
- Genome Scanning of the HXB/BXH Sets of Recombinant Inbred Strains of the Rat for Quantitative Trait Loci Associated with Conditioned Taste Aversion.
Bielavsk�, Edita; Kren, Vladim�r; Musilov�, Alena; Z�dek, V�clav; Pravenec, Michal // Behavior Genetics; Jan2002, Vol. 32 Issue 1, p51In the current study, we searched for quantitative trait loci (QTL) responsible for a conditioned taste aversion (CTA) measured as a decrease in the intake of a saccharin conditioned stimulus followed by an i.p. injection of 0.15 M LiCl (lithium chloride) (2 ml/100 g body weight). A genome...
- Reward: Serotonin promotes patience.
Welberg, Leonie // Nature Reviews Neuroscience; Aug2012, Vol. 13 Issue 9, p603The article discusses research being done on serotonin which references the study "Activation of dorsal raphe serotonin neurons is necessary for waiting for delayed rewards," K. W. Miyazaki, K. Miyazaki, and K. Doya in the 2012 issue of "Journal Neuroscience."
- Factors involved in the effects of losartan on endothelial dysfunction induced by aging in SHR.
Maeso, Rosauro; Rodrigo, Elena; Munoz-Garcia, Raquel; Navarro-Cid, Josefa; Ruilope, Luis M.; Cachofeiro, Victoria; Lahera, Vicente // Kidney International Supplement; Dec1998, Issue 68, pS-30Examines the factors involved in the effects of losartan on endothelial dysfunction induced by aging spontaneous hypertensive rats (SHR). Capacity of losartan treatment in reducing blood pressure levels; Association between hypertension and functional and structural changes in the vessel wall;...
