Citations with the tag: PHENYTOIN
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- Fosphenytoin will soon replace its older cousin.
Cerrato, Paul L. // RN; Oct96, Vol. 59 Issue 10, p70
Reports on the advantages of the drug fosphenytoin over phenytoin. Indications of use.
- Dilantin, at last.
R.M.D. // Cortlandt Forum; 8/25/95, Vol. 8 Issue 8, p87
Comments on a doctor's prescription for the daily intake of Dilantin (Phenytoin) in treating patients who present with puzzling, recurring symptoms of unknown etiology. Implications; Efficiency; Failure possibility.
- Dilantin doses.
P.G.O'C. // Cortlandt Forum; 8/25/96, Vol. 9 Issue 8, p91
Presents a response to the query on the correct dosage for the administration of Dilantin, generically known as phenytoin, in an adult. Determination of the correct dosage by a combination of the patient's weight, overall medical condition and clinical response; Recommendation for twice-daily...
- Controversy for Anti-Epileptic Prophylaxis in CNS Conditions.
Yu, Herta; Liang, Diana // AXON/ L'AXONE; Spring2006, Vol. 27 Issue 3, p28
The issue regarding prophylactic antiepileptic therapy to prevent seizure activity associated with acute central nervous system (CNS) conditions remains controversial, especially in the pediatric population. Seizures may be the initial presenting symptoms that bring the child to hospital. In...
Yu, Herta; Liang, Diana // Taber's Cyclopedic Medical Dictionary (2009); 2009, Issue 21, p1771
A definition of the term "phenytoin," which refers to an anticonvulsant drug used in treating patients with seizure disorders, is presented.
Yu, Herta; Liang, Diana // Reactions Weekly; 5/5/2012, Issue 1400, p33
The article describes the case of a 20-year-old woman, who had a 19-year history of seizures, who developed gingival hypertrophy while receiving phenytoin for seizures.
Yu, Herta; Liang, Diana // Reactions Weekly; 10/23/2010, Issue 1324, p24
The article describes a case of anticonvulsant hypersensitivity syndrome in a 47-year-old man who received lamotrigine and phenytoin for focal cryptogenic epilepsy.
Yu, Herta; Liang, Diana // Reactions Weekly; 7/7/2012, Issue 1409, p37
The article describes the case of a 54-year-old man who developed drug-induced hypersensitivity syndrome (DIHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome following the administration of phenytoin for convulsions.
Yu, Herta; Liang, Diana // Toxicological Sciences; Oct2006, Vol. 93 Issue 2, p450
A correction to the article "A Developmental Role for Ataxia-Telangiectasia Mutated in Protecting the Embryo From Spontaneous and Phenytoin-Enhanced Embryopathies in Culture" is presented.
Yu, Herta; Liang, Diana // Reactions Weekly; 5/21/2011, Issue 1352, p31
The article describes the case of a 60-year-old woman who developed purple glove syndrome while being treated with phenytoin for seizures.
- Phenytoin overdose.
Yu, Herta; Liang, Diana // Reactions Weekly; 9/15/2012, Issue 1419, p40
The article describes the case of a 4-year-old child who developed altered sensorium, involuntary head nodding movements and nystagmus after accidental ingestion of phenytoin.
Yu, Herta; Liang, Diana // Reactions Weekly; 5/19/2012, Issue 1402, p21
The article describes the case of a 46-year-old man who developed drug-induced hypersensitivity syndrome (DIHS) with reactivation of human herpesvirus-6 infection (HHV6) while receiving phenytoin and dexamethasone for hypovitaminosis D.
- Antiepileptic drugs.
Yu, Herta; Liang, Diana // Reactions Weekly; 6/2/2012, Issue 1404, p7
The article describes two cases of maculopapular eruptions and Stevens-Johnson syndrome in women while taking carbamazepine and phenytoin, respectively.
Yu, Herta; Liang, Diana // Reactions Weekly; 11/20/2010, Issue 1328, p36
The article describes a case of hypersensitivity syndrome manifesting as acute generalised exanthematous pustulosis in a 29-year-old woman during treatment with phenytoin for seizure prevention.
Yu, Herta; Liang, Diana // Reactions Weekly; 2/11/2012, Issue 1388, p25
The article describes the case of a three-year-old boy who developed anticonvulsant hypersensitivity syndrome and hypogammaglobulinaemia while under phenytoin treatment regimen for convulsions.
Yu, Herta; Liang, Diana // Reactions Weekly; 2/11/2012, Issue 1388, p25
The article describes the case of a 64-year-old woman who experienced generalized seizures after receiving phenytoin for repeated cholecystitis.
- Clobazam/phenobarbital/phenytoin interaction.
Yu, Herta; Liang, Diana // Reactions Weekly; 2/4/2012, Issue 1387, p14
The article describes the case of a 3-year-old girl who developed chorea after receiving phenytoin, phenobarbital and clobazam for generalised tonic-clonic seizures.
Yu, Herta; Liang, Diana // Reactions Weekly; 7/28/2012, Issue 1412, p38
The article describes the case of a 53-year-old woman with schizoaffective disorder who developed hypothermia after receiving phenytoin and risperidone.
- Acute Intoxication with 5,5--Diphenylhydantion (Dilantin Â®) Associated with Impairment of Biotransformation.
Gerber, Nicholas; Lynn, Robert // Annals of Internal Medicine; Nov72, Vol. 77 Issue 5, p765
Presents information on a study that measured plasma levels of diphenylhydantoin in an intoxicated patient and correlated with the clinical features. Methodology of the study; Results and discussion on the study.
- Oxcarbazepine/phenytoin interaction.
Gerber, Nicholas; Lynn, Robert // Reactions Weekly; 4/23/2011, Issue 1348/1349, p28
The article describes the case of a 67-year-old woman who developed increased phenytoin concentration and ataxia while receiving concomitant phenytoin and oxcarbazepine treatment.
- Fluorouracil/phenytoin interaction.
Gerber, Nicholas; Lynn, Robert // Reactions Weekly; 2/25/2012, Issue 1390, p18
The article describes the case of a 64-year-old woman taking oral phenytoin for epilepsy who developed central nervous system (CNS) disorders after treatment with fluorouracil for metastatic colorectal cancer was initiated.
Gerber, Nicholas; Lynn, Robert // Reactions Weekly; 1/29/2011, Issue 1336, p17
The article describes the clinical cases of four patients who developed Stevens-Johnson syndrome with cicatrising conjunctivitis after receiving dipyrone, phenytoin or sulfonamide.
Gerber, Nicholas; Lynn, Robert // Reactions Weekly; 11/26/2011, Issue 1379, p19
The article describes the case of a 49-year-old man who developed four episodes of apnoea and was intubated immediately after receiving intravenous (IV) fosphenytoin 18 phenytoin equivalent (PE) per kilogram over 15 minutes for status epilepticus.
Gerber, Nicholas; Lynn, Robert // Reactions Weekly; 7/9/2011, Issue 1359, p11
The article describes the case of a 48-year-old woman who developed thrombocytopenia while receiving treatment with phenytoin and azithromycin.
- Phenytoin Overviewï¿½ Metabolite Interference in Some Immunoassays Could Be Clinically Important.
Roberts, William L. // Archives of Pathology & Laboratory Medicine; Jul2004, Vol. 128 Issue 7, p734
Presents a letter to the editor on the article "Phenytoin Overview" Metabolite Interference in Some Immunoassays Could be Clinically Important," that was previously published in the journal "Archives of Pathology and Laboratory Medicine."
- Phenytoin Overviewï¿½Metabolite Interference in Some Immunoassays Could Be Clinically Important.
Rainey, Petrie M. // Archives of Pathology & Laboratory Medicine; Jul2004, Vol. 128 Issue 7, p734
Presents a response by the author to a letter to the editor on his article "Phenytoin Overview--Metabolite Interference in Some Immunoassays Could be Clinically Important," that was previously published in the journal "Archives of Pathology and Laboratory Medicine."
- Drug News.
Rainey, Petrie M. // RN; Feb91, Vol. 54 Issue 2, p109
Presents updates on drugs as of February 1991. Effect of phenytoin after head trauma; Approval of a biological product for the treatment of bladder cancer; Relation of isoniazid to acetaminophen toxicity.
- Tissue plasminogen activator and seizures: a clot-buster's secret life.
Pawlak, Robert; Strickland, Sidney // Journal of Clinical Investigation; 6/15/2002, Vol. 109 Issue 12, p1529
Talks about plasminogen activator and seizures. Factors contributing to the generation or facilitation of seizures; Role of phenytoin and related antiseizure agents; Neuronal effects of tissue plasminogen activators.
- Should phenytoin still be used for epilepsy?
Bird, Jonathan // Pulse; 4/29/2002, Vol. 62 Issue 17, p72
Provides answer to a question on the efficacy of phenytoin for epilepsy. Adverse effects of phenytoin; Information on phenytoin.
- Phenytoin hypersensitivity syndrome.
G�ng�r, E.; Alli, N.; �omoglu, S.; ��mc�oglu, C. // Neurological Sciences; Jun2001, Vol. 22 Issue 3, p261
Phenytoin hypersensitivity syndrome (PHS) is a rare, and important entity characterized by rash, fever, lymphadenopathy, leukocytosis with atypical lymphocytes, eosinophilia and associated hepatitis. In this article, we present the clinical, laboratory and histopathologic results of 5 cases of...
- Developmental neurotoxicity induced by therapeutic and illicit drugs
Vorhees, Charles V. // Environmental Health Perspectives Supplements; 1994 Supplement 2, Vol. 102, p145
No abstract available.
- What's new in drugs.
Rodman, Morton J. // RN; Jan84, Vol. 47 Issue 1, p101
Presents updates on several drugs as of January 1984. Risks of infusing high concentrations of intravenous phenytoin; Importance of reporting taste loss after taking in captopril; Link of the antidepressant irazodone with priapism.
- Diagnostically Confusing Complications of Diphenylhydantoin Therapy.
Sparberg, Marshall // Annals of Internal Medicine; Dec63, Vol. 59 Issue 6, p914
Explores the diagnostically confusing complications of diphenylhydantoin therapy. Metabolism of diphenylhydantoin; Hematologic complications; Reticuloendothelial complications; Metabolic complications.
- Interaction of Phenytoin and Primidone.
Reynolds, E.H.; Fenton, G.; Fenwick, P.; Johnson, A.L.; Laundy, M. // British Medical Journal; 6/14/1975, Vol. 2 Issue 5971, p594
Examines the combination of phenytoin and primidone in epileptic patients. Increase in the serum phenobarbitone; Correlation between serum phenytoin and the phenobarbitone; Effect of phenytoin on phenobarbitone.
- When you give phenytoin IV.
Fishel, Marilyn; Sauer, Shar; Allen, Jody // RN; Sep90, Vol. 53 Issue 9, p58
Presents a guideline for using phenytoin intravenous. Local reactions to phenytoin; Chemical contents of phenytoin; Tips in preventing purple glove syndrome.
- Acute Pulmonary Disease Caused by Phenytoin.
Michael, John R.; Rudin, Marilyn L. // Annals of Internal Medicine; Oct81, Vol. 95 Issue 4, p452
Examines a clinical case of acute pulmonary disease caused by phenytoin. Allergic reaction caused by phenytoin sodium; Case report of the patient; Discussions on the clinical findings.
- Thyroxine Replacement Requirements in Hypothyroid Patients Receiving Phenytoin.
Blackshear, Joseph L.; Schultz, Alvin L.; Napier, Jerold S.; Stuart, David D. // Annals of Internal Medicine; Sep83, Vol. 99 Issue 3, p341
Presents a case study on primary hypothyroidism in a patient on long-term thyroxine replacement who developed clinical hypothyroidism after starting phenytoin. Information on the patient; Conclusion.
- Phenytoin-valproate interaction: importance of saliva monitoring in epilepsy.
Knott, Christine; Hamshaw-Thomas, Anne; Reynolds, Felicity // British Medical Journal (Clinical Research Edition); 1/2/1982, Vol. 284 Issue 6308, p13
Discusses the interaction of phenytoin and sodium valproate. Importance of saliva monitoring in epilepsy; Degree of phenytoin binding; Effects of valproate concentration on phenytoin protein binding.
- Phenobarbital and Phenytoin for Seizures in Newborns.
Kirchner, Jeffrey T. // American Family Physician; 1/1/2000, Vol. 61 Issue 1, p206
Discusses the study `Phenobarbital Compared With Phenytoin for the Treatment of Neonatal Seizures,' by M.J. Painter and colleagues published in the August 12, 1999 issue of the `New England Journal of Medicine.'
- Effects of anticonvulsants on GLUT1-mediated glucose transport in GLUT1 deficiency syndrome in vitro.
Klepper, J�rg; Fl�rcken, Anne; Fischbarg, Jorge; Voit, Thomas // European Journal of Pediatrics; 2003, Vol. 162 Issue 2, p84
Facilitative type-1 glucose transporter (GLUT1) deficiency syndrome is caused by a defect of glucose transport into brain, resulting in an epileptic encephalopathy. Seizures respond effectively to a ketogenic diet, but a subgroup of patients require add-on anticonvulsant therapy or do not...
- Epilepsy experts seek non-drug therapies that spare skin, hair.
Pfeiffer, Naomi // Dermatology Times; Jul2002, Vol. 23 Issue 7, p24
Examines the efficacy of the anti-epileptic drugs Valproate and Phenytoin in treating patients with hirsutism. Side effects of the drugs; Reduction of the fragility of the hair; Availability of the drugs.
- Cutaneous reactions in patients with solitary cysticercus granuloma on phenytoin sodium.
Singh G; Kaushal S; Gupta M; Chander Chopra S // Journal of Neurology, Neurosurgery & Psychiatry; Feb2004, Vol. 75 Issue 2, p331
Several medical conditions are believed to be associated with an increased risk of cutaneous adverse reactions to anti-epileptic drugs. The aim of this study was to study the frequency and nature of cutaneous reactions in a cohort of patients being treated with phenytoin sodium for seizures, who...
- High incidence of a concentration-dependent skin reaction in children treated with phenytoin.
Wilson, J.T.; Höjer, B.; Tomson, G.; Rane, A.; Sjöqvist, F. // British Medical Journal; 6/17/1978, Vol. 1 Issue 6127, p1583
A particularly high incidence of rash was seen in children with epilepsy treated with phenytoin. Ten children with untreated epilepsy were therefore included in a prospective study and given either 3 (group 1) or 6 (group 2) mg of phenytoin/kg body weight/day for five days followed by 6 mg/kg...
- The Current Status of Diphenylhydantoin in Heart Disease.
Mercer, Edward N.; Osborne, John A. // Annals of Internal Medicine; Nov67, Vol. 67 Issue 5, p1084
Presents a review of studies on the use of diphenylhydantoin sodium for the treatment of cardiac arrhythmias. Background on the drug; Possible mechanisms of antiarrhythmic action of the drug; Cardiovascular effects of the drug; Methods of using the drug.
- Phenytoin-Induced Toxic Epidermal Necrolysis.
Gately, Leonard E.; Lam, Michael A. // Annals of Internal Medicine; Jul79, Vol. 91 Issue 1, p59
Presents a case report of toxic epidermal necrolysis associated with the administration of phenytoin alone. Details on the case; Mortality rate for toxic epidermal necrolysis; Symptoms of patients with toxic epidermal necrolysis before the skin eruption; Diagnosis of toxic epidermal necrolysis.
Gately, Leonard E.; Lam, Michael A. // Reactions Weekly; 12/18/2010, Issue 1332, p34
The article describes the case of a 43-year-old woman with a history of seizure disorder, who developed DRESS syndrome while under phenytoin treatment regimen.
Gately, Leonard E.; Lam, Michael A. // Reactions Weekly; 1/14/2012, Issue 1384, p45
The article describes the case of two women, aged 53 and 57 years, who both developed a mild rash and one woman developed a fever following treatment with phenytoin as well as dexamethasone after a meningioma surgery.
- Divided phenytoin.
R.M.D. // Cortlandt Forum; 1/25/95, Vol. 8 Issue 1, p73
Presents suggestions on the administration of phenytoin in three or four doses considering its half-life of 12 hours for epileptics. Formulation of phenytoin Dilantin as a single daily dose.
R.M.D. // Reactions Weekly; 03/01/2013, Issue 1441, p27
The article presents a case report of a 28-year-old man with reports including scholastic deterioration, aggressive behavior, sadness and decreased confidence, developed mood, behavior and cognitive symptoms during chronic phenytoin administration.
- The predictive value of MDR1, CYP2C9, and CYP2C19 polymorphisms for phenytoin plasma levels.
Kerb, R.; Aynacioglu, A.S.; Brockmoller, J.; Schlagenhaufer, R.; Bauer, S.; Szekeres, T.; Hamwi, A.; Fritzer-Szekeres, M.; Baumgartner, C.; Ongen, H.Z.; Guzelbey, P.; Roots, I.; Brinkmann, U. // Pharmacogenomics Journal; 2001, Vol. 1 Issue 3, p204
Presents a study which determined the predictive value of the combination of the genetic analysis of polymorphisms in CYP2C9 with that in MDR1 for phenytoin blood concentrations. Description of materials and methods used in the study; Value of MDR1 and CYP2C9 genotyping for routine use in...