Citations with the tag: PHENYTOIN
Results 1 - 50
- Fosphenytoin will soon replace its older cousin.
Cerrato, Paul L. // RN; Oct96, Vol. 59 Issue 10, p70
Reports on the advantages of the drug fosphenytoin over phenytoin. Indications of use.
- Dilantin, at last.
R.M.D. // Cortlandt Forum; 8/25/95, Vol. 8 Issue 8, p87
Comments on a doctor's prescription for the daily intake of Dilantin (Phenytoin) in treating patients who present with puzzling, recurring symptoms of unknown etiology. Implications; Efficiency; Failure possibility.
- Dilantin doses.
P.G.O'C. // Cortlandt Forum; 8/25/96, Vol. 9 Issue 8, p91
Presents a response to the query on the correct dosage for the administration of Dilantin, generically known as phenytoin, in an adult. Determination of the correct dosage by a combination of the patient's weight, overall medical condition and clinical response; Recommendation for twice-daily...
- Acute Intoxication with 5,5--Diphenylhydantion (Dilantin ï¿½) Associated with Impairment of Biotransformation.
Gerber, Nicholas; Lynn, Robert // Annals of Internal Medicine; Nov72, Vol. 77 Issue 5, p765
Presents information on a study that measured plasma levels of diphenylhydantoin in an intoxicated patient and correlated with the clinical features. Methodology of the study; Results and discussion on the study.
- Controversy for Anti-Epileptic Prophylaxis in CNS Conditions.
Yu, Herta; Liang, Diana // AXON/ L'AXONE; Spring2006, Vol. 27 Issue 3, p28
The issue regarding prophylactic antiepileptic therapy to prevent seizure activity associated with acute central nervous system (CNS) conditions remains controversial, especially in the pediatric population. Seizures may be the initial presenting symptoms that bring the child to hospital. In...
Yu, Herta; Liang, Diana // Taber's Cyclopedic Medical Dictionary (2009); 2009, Issue 21, p1771
A definition of the term "phenytoin," which refers to an anticonvulsant drug used in treating patients with seizure disorders, is presented.
- Phenytoin Overviewï¿½ Metabolite Interference in Some Immunoassays Could Be Clinically Important.
Roberts, William L. // Archives of Pathology & Laboratory Medicine; Jul2004, Vol. 128 Issue 7, p734
Presents a letter to the editor on the article "Phenytoin Overview" Metabolite Interference in Some Immunoassays Could be Clinically Important," that was previously published in the journal "Archives of Pathology and Laboratory Medicine."
- Phenytoin Overviewï¿½Metabolite Interference in Some Immunoassays Could Be Clinically Important.
Rainey, Petrie M. // Archives of Pathology & Laboratory Medicine; Jul2004, Vol. 128 Issue 7, p734
Presents a response by the author to a letter to the editor on his article "Phenytoin Overview--Metabolite Interference in Some Immunoassays Could be Clinically Important," that was previously published in the journal "Archives of Pathology and Laboratory Medicine."
- Interaction of azapropazone with phenytoin.
Rainey, Petrie M. // British Medical Journal (Clinical Research Edition); 5/8/82, Vol. 284 Issue 6326, p1373
Investigates the effects of azapropazone on steady-state plasma phenytoin concentrations in five volunteers. Presence of plasma phenytoin concentration; Comparison of concentration in five volunteers; Effect of azapropazone on plasma phenytoin concentrations.
- Drug News.
Rainey, Petrie M. // RN; Feb91, Vol. 54 Issue 2, p109
Presents updates on drugs as of February 1991. Effect of phenytoin after head trauma; Approval of a biological product for the treatment of bladder cancer; Relation of isoniazid to acetaminophen toxicity.
- Tissue plasminogen activator and seizures: a clot-buster's secret life.
Pawlak, Robert; Strickland, Sidney // Journal of Clinical Investigation; 6/15/2002, Vol. 109 Issue 12, p1529
Talks about plasminogen activator and seizures. Factors contributing to the generation or facilitation of seizures; Role of phenytoin and related antiseizure agents; Neuronal effects of tissue plasminogen activators.
- Seizure prodrug.
Rodgers, Katie // Drug Topics; 9/16/96, Vol. 140 Issue 18, p41
Reports on the availability of the injectable prodrug of phenytoin called Fosphenytoin, from Parke-Davis. Indication of the drug for the acute treatment and control of generalized convulsive status epilepticus; Faster administration of the drug than phenytoin; Side effects; Requirements for...
- How do you stop a seizure? Two experts count the ways.
Portyansky, Elena // Drug Topics; 10/4/99, Vol. 143 Issue 19, p28
Provides information on the drugs used to treat a patient experiencing an acute seizure. Commonly used drugs for seizure emergencies; Use of phenytoin; Other therapeutic options for patients experiencing seizure.
- Should phenytoin still be used for epilepsy?
Bird, Jonathan // Pulse; 4/29/2002, Vol. 62 Issue 17, p72
Provides answer to a question on the efficacy of phenytoin for epilepsy. Adverse effects of phenytoin; Information on phenytoin.
- Phenytoin hypersensitivity syndrome.
G�ng�r, E.; Alli, N.; �omoglu, S.; ��mc�oglu, C. // Neurological Sciences; Jun2001, Vol. 22 Issue 3, p261
Phenytoin hypersensitivity syndrome (PHS) is a rare, and important entity characterized by rash, fever, lymphadenopathy, leukocytosis with atypical lymphocytes, eosinophilia and associated hepatitis. In this article, we present the clinical, laboratory and histopathologic results of 5 cases of...
- Developmental neurotoxicity induced by therapeutic and illicit drugs
Vorhees, Charles V. // Environmental Health Perspectives Supplements; 1994 Supplement 2, Vol. 102, p145
No abstract available.
- What's new in drugs.
Rodman, Morton J. // RN; Jan84, Vol. 47 Issue 1, p101
Presents updates on several drugs as of January 1984. Risks of infusing high concentrations of intravenous phenytoin; Importance of reporting taste loss after taking in captopril; Link of the antidepressant irazodone with priapism.
- Malabsorption of frusemide caused by phenytoin.
Fine, Adrian; Henderson, I.S.; Morgan, D.R.; Tilstone, W.J. // British Medical Journal; 10/22/1977, Vol. 2 Issue 6094, p1061
Examines the malabsorption of frusemide caused by phenytoin. Effect of phenytoin on the absorption of frusemide; Renal response to frusemide; Mechanism of the malabsorption.
- Diagnostically Confusing Complications of Diphenylhydantoin Therapy.
Sparberg, Marshall // Annals of Internal Medicine; Dec63, Vol. 59 Issue 6, p914
Explores the diagnostically confusing complications of diphenylhydantoin therapy. Metabolism of diphenylhydantoin; Hematologic complications; Reticuloendothelial complications; Metabolic complications.
- Interaction of Phenytoin and Primidone.
Reynolds, E.H.; Fenton, G.; Fenwick, P.; Johnson, A.L.; Laundy, M. // British Medical Journal; 6/14/1975, Vol. 2 Issue 5971, p594
Examines the combination of phenytoin and primidone in epileptic patients. Increase in the serum phenobarbitone; Correlation between serum phenytoin and the phenobarbitone; Effect of phenytoin on phenobarbitone.
- When you give phenytoin IV.
Fishel, Marilyn; Sauer, Shar; Allen, Jody // RN; Sep90, Vol. 53 Issue 9, p58
Presents a guideline for using phenytoin intravenous. Local reactions to phenytoin; Chemical contents of phenytoin; Tips in preventing purple glove syndrome.
- Acute Pulmonary Disease Caused by Phenytoin.
Michael, John R.; Rudin, Marilyn L. // Annals of Internal Medicine; Oct81, Vol. 95 Issue 4, p452
Examines a clinical case of acute pulmonary disease caused by phenytoin. Allergic reaction caused by phenytoin sodium; Case report of the patient; Discussions on the clinical findings.
- Thyroxine Replacement Requirements in Hypothyroid Patients Receiving Phenytoin.
Blackshear, Joseph L.; Schultz, Alvin L.; Napier, Jerold S.; Stuart, David D. // Annals of Internal Medicine; Sep83, Vol. 99 Issue 3, p341
Presents a case study on primary hypothyroidism in a patient on long-term thyroxine replacement who developed clinical hypothyroidism after starting phenytoin. Information on the patient; Conclusion.
- Phenytoin-valproate interaction: importance of saliva monitoring in epilepsy.
Knott, Christine; Hamshaw-Thomas, Anne; Reynolds, Felicity // British Medical Journal (Clinical Research Edition); 1/2/1982, Vol. 284 Issue 6308, p13
Discusses the interaction of phenytoin and sodium valproate. Importance of saliva monitoring in epilepsy; Degree of phenytoin binding; Effects of valproate concentration on phenytoin protein binding.
- Phenobarbital and Phenytoin for Seizures in Newborns.
Kirchner, Jeffrey T. // American Family Physician; 1/1/2000, Vol. 61 Issue 1, p206
Discusses the study `Phenobarbital Compared With Phenytoin for the Treatment of Neonatal Seizures,' by M.J. Painter and colleagues published in the August 12, 1999 issue of the `New England Journal of Medicine.'
- Effects of anticonvulsants on GLUT1-mediated glucose transport in GLUT1 deficiency syndrome in vitro.
Klepper, J�rg; Fl�rcken, Anne; Fischbarg, Jorge; Voit, Thomas // European Journal of Pediatrics; 2003, Vol. 162 Issue 2, p84
Facilitative type-1 glucose transporter (GLUT1) deficiency syndrome is caused by a defect of glucose transport into brain, resulting in an epileptic encephalopathy. Seizures respond effectively to a ketogenic diet, but a subgroup of patients require add-on anticonvulsant therapy or do not...
- Potential Hazards of Hydantion Use.
Klepper, J�rg; Fl�rcken, Anne; Fischbarg, Jorge; Voit, Thomas // Annals of Internal Medicine; Dec72, Vol. 77 Issue 6, p998
Focuses on diphenylhydantoin, one of the most commonly used drugs in the management of seizure disorders. Information on immunological abnormalities; Role of hydantoins in seizure disorders.
- Epilepsy experts seek non-drug therapies that spare skin, hair.
Pfeiffer, Naomi // Dermatology Times; Jul2002, Vol. 23 Issue 7, p24
Examines the efficacy of the anti-epileptic drugs Valproate and Phenytoin in treating patients with hirsutism. Side effects of the drugs; Reduction of the fragility of the hair; Availability of the drugs.
- Serum Phenytoin Concentrations in Uremia.
Burgess, Ellen D.; Friel, Patrick N.; Blair, Andrew D.; Raisys, Vidmantas A. // Annals of Internal Medicine; Jan81, Vol. 94 Issue 1, p59
Focuses on the techniques in ascertaining serum phenytoin concentrations. Difference of the pharmacokinetics of phenytoin in uremic patients and in normal persons; Information on phenytoin; Comparison of serum phenytoin concentrations ascertained by enzyme-multiplied immunoassay and gas liquid...
- LETTERS .
Hadley, David; Renouf, Tia // CJEM: Canadian Journal of Emergency Medicine; May2002, Vol. 4 Issue 3, p171
Comments on authors' A. Ip and T. Renouf's articles regarding serotonin syndrome. Decision to paralyze the patient to stop ongoing seizure-induced rhabdomyolysis; Use of phenytoin in overdose patients; Treatment of hyperthemia with aggressive external cooling; Irrelevance of urine toxicology...
- Development of antiepileptic hypersensitivity syndrome after phenytoin treatment.
�zdemir, �ner // Turkish Journal of Pediatrics; Jan/Feb2010, Vol. 52 Issue 1, p111
A letter to the editor is presented in response to the article "Antiepileptic hypersensitivity and DRESS syndrome due to phenytoin in two pediatric cases," by Shahnaz Armin, Zahara Chavoshzadeh and Nima Rezaei in the journal's previous issue.
- Comparing Dilantin formulations.
R.M.D. // Cortlandt Forum; 9/25/96, Vol. 9 Issue 9, p121
Reports on the difference in the pharmacokinetics of phenytoin Dilantin tablets or suspension compared with that of Dylantic capsules used in the control of seizure disorders. Dosage.
- Phenothiazine-Induced Phenytoin Intoxication.
Vincent, Frederick M. // Annals of Internal Medicine; Jul80 Part 1, Vol. 93 Issue 1, p56
Describes two patients with clinically significant phenytoin intoxication that occurred during concurrent administration of thioridazine. Medication given to the patients; Explanation for the observed toxicity; Implications for physicians.
Aronson, J.K.; Hardman, M.; Reynolds, D.J.M. // BMJ: British Medical Journal (International Edition); 11/14/92, Vol. 305 Issue 6863, p1215
Investigates the effect of phenytoin, an anticonvulsant drug used in the management of epilepsy. Toxicity of the drug; Query on the metabolism of phenytoin; Enumeration of several factors affecting plasma phenytoin concentration.
- Cutaneous reactions in patients with solitary cysticercus granuloma on phenytoin sodium.
Singh G; Kaushal S; Gupta M; Chander Chopra S // Journal of Neurology, Neurosurgery & Psychiatry; Feb2004, Vol. 75 Issue 2, p331
Several medical conditions are believed to be associated with an increased risk of cutaneous adverse reactions to anti-epileptic drugs. The aim of this study was to study the frequency and nature of cutaneous reactions in a cohort of patients being treated with phenytoin sodium for seizures, who...
- High incidence of a concentration-dependent skin reaction in children treated with phenytoin.
Wilson, J.T.; Höjer, B.; Tomson, G.; Rane, A.; Sjöqvist, F. // British Medical Journal; 6/17/1978, Vol. 1 Issue 6127, p1583
A particularly high incidence of rash was seen in children with epilepsy treated with phenytoin. Ten children with untreated epilepsy were therefore included in a prospective study and given either 3 (group 1) or 6 (group 2) mg of phenytoin/kg body weight/day for five days followed by 6 mg/kg...
- The Current Status of Diphenylhydantoin in Heart Disease.
Mercer, Edward N.; Osborne, John A. // Annals of Internal Medicine; Nov67, Vol. 67 Issue 5, p1084
Presents a review of studies on the use of diphenylhydantoin sodium for the treatment of cardiac arrhythmias. Background on the drug; Possible mechanisms of antiarrhythmic action of the drug; Cardiovascular effects of the drug; Methods of using the drug.
- Phenytoin-Induced Toxic Epidermal Necrolysis.
Gately, Leonard E.; Lam, Michael A. // Annals of Internal Medicine; Jul79, Vol. 91 Issue 1, p59
Presents a case report of toxic epidermal necrolysis associated with the administration of phenytoin alone. Details on the case; Mortality rate for toxic epidermal necrolysis; Symptoms of patients with toxic epidermal necrolysis before the skin eruption; Diagnosis of toxic epidermal necrolysis.
- Hydantoin-Induced Pseudo-Pseudolymphoma.
Gams, Richard A.; Neal, Joseph A.; Conrad, Fred G. // Annals of Internal Medicine; Sep68, Vol. 69 Issue 3, p557
Examines the pathologic aspects of hydantoin-associated lymphadenopathy and reconsiders the possible interrelationships of the various manifestations of the syndrome. Effect of the discontinuation of diphenylhydantoin on adenopathy; Recurrence of the syndrome as a fatal malignant lymphoma;...
- Induction of sex hormone binding globulin by phenytoin.
Victor, Arne; Lundberg, P.O.; Johansson, Elof D.B. // British Medical Journal; 10/8/1977, Vol. 2 Issue 6092, p934
Investigates the induction of sex hormone binding globulin (SHBG) by phenytoin. Study on the SHBG concentration in women with epilepsy treated with phenytoin; Findings on the effects of phenytoin; Conclusion on the function of SHBG concentration.
- Factors Affecting the Free Plasma Fraction of Phenytoin in Patients with Epilepsy.
Jiménez, M.C.; Durán, J.A.; Abad ín, J.A. // Clinical Drug Investigation; 1998, Vol. 15 Issue 2, p153
The variability and possible factors modifying the free plasma fraction of phenytoin were investigated in 134 patients with epilepsy undergoing long-term treatment. The total and free plasma concentrations of phenytoin were determined using fluorescent polarisation immunoassay. Concentrations of...
- Fosphenytoin and Phenytoin in Patients with Status Epilepticus: Improved Tolerability versus Increased Costs.
deToledo, J.C.; Ramsay, R. // Drug Safety; Jun2000, Vol. 22 Issue 6, p459
Tonic-clonic status epilepticus (TCSE) is the most common neurological emergency and affects approximately 60 000 patients each year in the US. The risk of complications increases substantially as TCSE lasts longer than 60 minutes. Ideally, drugs used to treat this condition should be well...
deToledo, J.C.; Ramsay, R. // Reactions Weekly; 5/21/2011, Issue 1352, p31
The article describes the case of a 60-year-old woman who developed purple glove syndrome while being treated with phenytoin for seizures.
deToledo, J.C.; Ramsay, R. // Reactions Weekly; 5/22/2010, Issue 1302, p38
The article describes the case of a 26-year-old woman who experienced purple glove syndrome after an intravenous infusion of phenytoin.
deToledo, J.C.; Ramsay, R. // Reactions Weekly; 1/29/2011, Issue 1336, p17
The article describes the clinical cases of four patients who developed Stevens-Johnson syndrome with cicatrising conjunctivitis after receiving dipyrone, phenytoin or sulfonamide.
deToledo, J.C.; Ramsay, R. // Reactions Weekly; 1/29/2011, Issue 1336, p38
This article describes a case study of a 40-year-old woman with a history of dissociative psychomotoric seizures who developed purple glove syndrome during treatment with phenytoin.
deToledo, J.C.; Ramsay, R. // Reactions Weekly; 5/19/2012, Issue 1402, p21
The article describes the case of a 46-year-old man who developed drug-induced hypersensitivity syndrome (DIHS) with reactivation of human herpesvirus-6 infection (HHV6) while receiving phenytoin and dexamethasone for hypovitaminosis D.
- Antiepileptic drugs.
deToledo, J.C.; Ramsay, R. // Reactions Weekly; 6/2/2012, Issue 1404, p7
The article describes two cases of maculopapular eruptions and Stevens-Johnson syndrome in women while taking carbamazepine and phenytoin, respectively.
deToledo, J.C.; Ramsay, R. // Reactions Weekly; 10/23/2010, Issue 1324, p24
The article describes a case of anticonvulsant hypersensitivity syndrome in a 47-year-old man who received lamotrigine and phenytoin for focal cryptogenic epilepsy.
deToledo, J.C.; Ramsay, R. // Reactions Weekly; 11/20/2010, Issue 1328, p36
The article describes a case of hypersensitivity syndrome manifesting as acute generalised exanthematous pustulosis in a 29-year-old woman during treatment with phenytoin for seizure prevention.