Citations with the tag: OLFACTORY receptors
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- Why You Smell.
// Current Science; 10/15/2010, Vol. 96 Issue 4, p9The article offers information on the olfactory receptors present in the human nose as nerve cells used for the sense of smelling.
- SCIENCE NEWS.
Hamalainen, Karina; Crane, Cody; Gaidos, Susan; Dehart, Charlye // Science World; 1/2/2012, Vol. 68 Issue 7, p2This section offers news briefs related to science including a study on scent receptors, an undercover rescue operation for a baby gorilla in Congo, and underestimation of the caloric content of fast foods by 11- to 20-year-old individuals.
- Follow your nose.
Barrett, Michael // New Statesman; 10/31/2011, Vol. 140 Issue 5077, p14The article discusses the use of animals such as dogs and rats to detect disease by using their sense of smell.
- Sensory experience and rest control survival of newborn neurons in adults.
Barrett, Michael // Biomedical Market Newsletter; 9/12/2011, Vol. 21, p114The article reports on a study that revealed both the olfactory experience during feeding and subsequent period of rest contributes to the likelihood that an olfactory neuron will escape elimination and be incorporated into existing circuitry.
- Table of Contents.
Barrett, Michael // Chemical Senses; Jun2013, Vol. 38 Issue 5, pNPThe table of contents for the June 2013 issue of "Chemical Senses" is presented.
- Interactions of Odorants with Olfactory Receptors and Other Preprocessing Mechanisms: How Complex and Difficult to Predict?
Rospars, Jean-Pierre // Chemical Senses; May2013, Vol. 38 Issue 4, p283In this issue of Chemical Senses, Munch et al. present a thorough analysis of how mixtures of odorants interact with olfactory receptors (ORs) borne by olfactory receptor neurons (ORNs). Using fruit fly ORNs expressing the receptor OR22a, they provide a clear example of mixture interaction and...
- Silkworm Smell Refines the Electronic Nose.
ANDERSON, ALISHA // Australasian Science; Oct2009, Vol. 30 Issue 9, p30The article reports on the odorant receptors in the silkworm. These receptors are found in the initial release of the silkworm genome by scientists at Commonwealth Scientific and Industrial Research Organisation (CSIRO), HortResearch in New Zealand. They can be developed into electronic nose...
- Articles Highlighted.
Meyerhof, Wolfgang // Chemical Senses; Nov2012, Vol. 37 Issue 9, p767An introduction is presented in which the editor discusses various reports within the issue on topics including wasabi preparations, combinatorial odorant receptor (OR) code and visualization and identification of taste bud cells.
- Genes may explain why some people turn their noses up at meat.
Meyerhof, Wolfgang // Food Engineering & Ingredients; May/Jun2012, Vol. 37 Issue 2, p6The article focuses on a study that informs that a gene linked to an odour receptor is responsible for detecting a compound androstenone found in mammals meat especially pork.
- Specific Entrainment of Mitral Cells during Gamma Oscillation in the Rat Olfactory Bulb.
David, Fran�ois O.; Hugues, Etienne; Cenier, Tristan; Fourcaud-Trocm�, Nicolas; Buonviso, Nathalie // PLoS Computational Biology; Oct2009, Vol. 5 Issue 10, p1Local field potential (LFP) oscillations are often accompanied by synchronization of activity within a widespread cerebral area. Thus, the LFP and neuronal coherence appear to be the result of a common mechanism that underlies neuronal assembly formation. We used the olfactory bulb as a model to...
- Calcium-stores mediate adaptation in axon terminals of Olfactory Receptor Neurons in Drosophila.
David, Fran�ois O.; Hugues, Etienne; Cenier, Tristan; Fourcaud-Trocm�, Nicolas; Buonviso, Nathalie // BMC Neuroscience; 2011 Supplement 1, Vol. 12 Issue Suppl 1, p105The article presents a study which analyzes the odor-induced calcium activity in the axon terminals of olfactory receptor neurons (ORNs) in Drosophila. It is said that sensory neurons tend to adapt to variable ambient conditions, such as the duration or repetition of a stimulus, and this...
- How big is the gap between olfactory detection and recognition of aliphatic aldehydes?
Laska, Matthias; Ringh, Anna // Attention, Perception & Psychophysics; Apr2010, Vol. 72 Issue 3, p806The aim of the present study was to determine the magnitude of the difference in concentration between olfactory detection and recognition thresholds of aliphatic aldehydes. To this end, we first determined olfactory detection thresholds for n-butanal, n-pentanal, n-hexanal, n-heptanal, and...
- Smell joins noise and light in the making of white.
Griggs, Jessica // New Scientist; 11/24/2012, Vol. 216 Issue 2892, p11The article reports on research published in "PNAS" by scientist Noam Sobel and team on the creation of aromas which are the olfactory version of white noise. The researchers developed mixtures of various odors and asked study participants to distinguish them. It is suggested that such mixtures...
- Common peptides shed light on evolution of Olfactory Receptors.
Gottlieb, Assaf; Olender, Tsviya; Lancet, Doron; Horn, David // BMC Evolutionary Biology; 2009, Vol. 9, Special section p1Background: Olfactory Receptors (ORs) form the largest multigene family in vertebrates. Their evolution and their expansion in the vertebrate genomes was the subject of many studies. In this paper we apply a motif-based approach to this problem in order to uncover evolutionary characteristics....
- Strongest Repellent Found.
SPIVACK, CAROLINE // Discover; Jan/Feb2012, Vol. 33 Issue 1, p58The article reports on the discovery by biologist Laurence Zwiebel of an insect repellent compound called VUAA1 that works by the disruption of a receptor in the insect olfactory system, preventing it from sensing prey.
- Embryonic Origin of Olfactory Circuitry in Drosophila: Contact and Activity-Mediated Interactions Pattern Connectivity in the Antennal Lobe.
Prieto-Godino, Lucia L.; Diegelmann, Soeren; Bate, Michael // PLoS Biology; Oct2012, Vol. 10 Issue 10, p1Olfactory neuropiles across different phyla organize into glomerular structures where afferents from a single olfactory receptor class synapse with uniglomerular projecting interneurons. In adult Drosophila, olfactory projection interneurons, partially instructed by the larval olfactory system...
- Non-synaptic inhibition between grouped neurons in an olfactory circuit.
Su, Chih-Ying; Menuz, Karen; Reisert, Johannes; Carlson, John R. // Nature; 12/6/2012, Vol. 492 Issue 7427, p66Diverse sensory organs, including mammalian taste buds and insect chemosensory sensilla, show a marked compartmentalization of receptor cells; however, the functional impact of this organization remains unclear. Here we show that compartmentalized Drosophila olfactory receptor neurons (ORNs)...
- Articles Highlighted.
Meyerhof, Wolfgang // Chemical Senses; Jan2013, Vol. 38 Issue 1, p1An introduction is presented in which the author discusses various reports the issue on topics such as the ligand profile of the odorant receptor (OR) of a mosquito, neural representation of odorants following sensory deprivation and modulation of sensory irritation.
- Articles Highlighted.
Meyerhof, Wolfgang // Chemical Senses; Mar2013, Vol. 38 Issue 3, p187An introduction is presented in which the editor discusses various reports within the issue on topics including the impact of serotonin reuptake inhibitor on rats' appetitive licking responses, olfactory knowledge, and the inhibition of insect odorant receptors by amiloride derivatives.
- Odor Classification: A Review of Factors Influencing Perception-Based Odor Arrangements.
Kaeppler, Kathrin; Mueller, Friedrich // Chemical Senses; Mar2013, Vol. 38 Issue 3, p189Decoding the psychological dimensions of human odor perception has long been a central issue of olfactory research. Odor scientists as well as fragrance professionals have tried to establish comprehensive standards for the description, measurement, and prediction of odor quality characteristics....
- Sensory processing: Follow the smell.
Welberg, Leonie // Nature Reviews Neuroscience; Feb2013, Vol. 14 Issue 2, p81The article reports presents a study on the olfactory receptor neurons (ORNs) of Drosophila or fruit-flies which send axons to their brain to lateralize odours through its antenna.
- The odor stick identification test for Japanese differentiates Parkinson's disease from multiple system atrophy and progressive supra nuclear palsy.
Welberg, Leonie // BMC Neurology; 2011, Vol. 11 Issue 1, p157The article focuses on the study of differentiation of Parkinson's disease (PD) from multiple system atrophy (MSA-P) and progressive supra nuclear palsy (PSP) by odor stick identification test for Japanese (OSIT-J). The olfactory function was evaluated through OSIT-J test in 94 Japanese patients...
- SECURITY TECHNOLOGY: Honey trap.
Zolfagharifard, Ellie // Engineer (Online Edition); 3/28/2011, p28The article focuses on the government funded project which aims at harnessing the olfactory ability of bees against terrorism. Researchers in Hertfordshire, England have discovered that honeybees have an even keener sense of smell than anyone first expected. A device with sensor integrated live...
- SECURITY TECHNOLOGY: Insect innovation medical detectors.
Zolfagharifard, Ellie // Engineer (Online Edition); 3/28/2011, p29The article focuses on the research conducted by London School of Hygiene and Tropical Medicine to demonstrate the olfactory abilities of honeybees in diagnoses of disease.
- Personal receptor repertoires: olfaction as a model.
Olender, Tsviya; Waszak, Sebastian M.; Viavant, Maya; Khen, Miriam; Ben-Asher, Edna; Reyes, Alejandro; Nativ, Noam; Wysocki, Charles J.; Dongliang Ge; Lancet, Doron // BMC Genomics; 2012, Vol. 13 Issue 1, p414Background: Information on nucleotide diversity along completely sequenced human genomes has increased tremendously over the last few years. This makes it possible to reassess the diversity status of distinct receptor proteins in different human individuals. To this end, we focused on the...
- Chemical communication by infochemicals.
Klaschka, Ursula // Environmental Science & Pollution Research; Jun2009, Vol. 16 Issue 4, p367The article discusses the significance of knowledge of the basic steps of the reaction cascade of the olfactory perception which is needed to understand the chemical communication by infochemicals. It presents a generalized scheme depicting chemical communication by infochemicals. It also notes...
- Olfactory discrimination largely persists in mice with defects in odorant receptor expression and axon guidance.
Klaschka, Ursula // Neural Development; 2012, Vol. 7 Issue 1, p17The article focuses on a study conducted to analyze the persistence of olfactory discrimination in mice. Downregulation of nearly one quarter of all odorant receptor genes in 3GnT2-/- mice compared to controls was revealed in microanalysis. The increase in the number of neurons expressing some...
- Functional Evidence of Multidrug Resistance Transporters (MDR) in Rodent Olfactory Epithelium.
Molinas, Adrien; Sicard, Gilles; Jakob, Ingrid // PLoS ONE; May2012, Vol. 7 Issue 5, p1Background: P-glycoprotein (Pgp) and multidrug resistance-associated protein (MRP1) are membrane transporter proteins which function as efflux pumps at cell membranes and are considered to exert a protective function against the entry of xenobiotics. While evidence for Pgp and MRP transporter...
- Binaral Rivalry in the Presence of Visual Perceptual and Semantic Influences.
Chen, Jennifer; Wen Zhou; Chen, Denise // PLoS ONE; Oct2012, Vol. 7 Issue 10, Special section p1When two different odorants are presented simultaneously to the two nostrils, we experience alternations in olfactory percepts, a phenomenon called binaral rivalry. Little is known about the nature of such alternations. Here we investigate this issue by subjecting unstable and stable olfactory...
- Predicting the Receptive Range of Olfactory Receptors.
Haddad, Rafi; Carmel, Liran; Sobel, Noam; Harel, David // PLoS Computational Biology; Feb2008, Vol. 4 Issue 2, p1Although the family of genes encoding for olfactory receptors was identified more than 15 years ago, the difficulty of functionally expressing these receptors in an heterologous system has, with only some exceptions, rendered the receptive range of given olfactory receptors largely unknown....
- High-Resolution Copy-Number Variation Map Reflects Human Olfactory Receptor Diversity and Evolution.
Hasin, Yehudit; Olender, Tsviya; Khen, Miriam; Gonzaga-Jauregui, Claudia; Kim, Philip M.; Eckehart Urban, Alexander; Snyder, Michael; Gerstein, Mark B.; Lancet, Doron; Korbel, Jan O. // PLoS Genetics; Nov2008, Vol. 4 Issue 11, p1Olfactory receptors (ORs), which are involved in odorant recognition, form the largest mammalian protein superfamily. The genomic content of OR genes is considerably reduced in humans, as reflected by the relatively small repertoire size and the high fraction (~55%) of human pseudogenes. Since...
- Effects of seasonality and moult cycle on the proliferation of nerve cells and on the labelling of ecdysone receptors in an estuarine crab.
Hollmann, Gabriela; Fonseca, Duane; Allodi, Silvana; Martinez, Pablo; Nery, Luiz // Journal of Comparative Physiology A: Neuroethology, Sensory, Neu; Mar2011, Vol. 197 Issue 3, p293Decapod crustaceans show proliferation of the nerve cells in the olfactory lobe throughout their lives. However, the regulation of this process is still poorly understood, since it may vary with endogenous and exogenous factors. The objective of the present investigation was to quantify the...
- Avid interactions underlie the Lys63-linked polyubiquitin binding specificities observed for UBA domains.
Sims, Joshua J.; Haririnia, Aydin; Dickinson, Bryan C.; Fushman, David; Cohen, Robert E. // Nature Structural & Molecular Biology; Aug2009, Vol. 16 Issue 8, p883Ubiquitin (denoted Ub) receptor proteins as a group must contain a diverse set of binding specificities to distinguish the many forms of polyubiquitin (polyUb) signals. Previous studies suggested that the large class of ubiquitin-associated (UBA) domains contains members with intrinsic...
- A new challenge-development of test systems for the infochemical effect.
Klaschka, Ursula // Environmental Science & Pollution Research; Jun2009, Vol. 16 Issue 4, p370The article presents a research study on the development of test systems for the infochemical effect. It provides the background, aim, and scope, results, recommendations and conclusions, and perspectives of the study. It also notes that the test systems presented in the study are based on the...
- Multisensory integration: an inner tongue puts an outer nose in context.
Yeshurun, Yaara; Sobel, Noam // Nature Neuroscience; Feb2010, Vol. 13 Issue 2, p148The article discusses a study conducted to test if taste influences smell, published within the issue. It states that on the basis of the procedure called social transmission of food preference (STFP) involved in the study, it was found that inactivating primary gustatory cortex alters olfactory...
- Downregulation of Fzd6 and Cthrc1 and upregulation of olfactory receptors and protocadherins by dietary beta-carotene in lungs of Bcmo1-/- mice.
van Helden, Yvonne G. J.; Godschalk, Roger W.; Heil, Sandra G.; Bunschoten, Annelies; Hessel, Susanne; Amengual, Jaume; Bonet, M. Luisa; von Lintig, Johannes; van Schooten, Frederik J.; Keijer, Jaap // Carcinogenesis; Aug2010, Vol. 31 Issue 8, p1329An ongoing controversy exists on beneficial versus harmful effects of high beta-carotene (BC) intake, especially for the lung. To elucidate potential mechanisms, we studied effects of BC on lung gene expression. We used a beta-carotene 15,15'-monooxygenase 1 (Bcmo1) knockout mouse (Bcmo1-/-)...
- Development: Hedgehog does the two-step.
Welberg, Leonie // Nature Reviews Neuroscience; Nov2010, Vol. 11 Issue 11, p732The article focuses on the study regarding the capability of Drosophila melanogaster, two-stage Hedgehog (HH) signalling to contribute to the spatial arrangement of different classes of olfactory receptor neuron (ORN) cell bodies. It notes the occurrence of HH signalling when it binds to and...
- Common variants in the regulative regions of
GRIA1 and GRIA3 receptor genes are associated
with migraine susceptibility.
Formicola, Daniela; Aloia, Andrea; Sampaolo, Simone; Farina, Olimpia; Diodato, Daria; Griffiths, Lyn R.; Gianfrancesco, Fernando; Di Iorio, Giuseppe; Esposito, Teresa // BMC Medical Genetics; 2010, Vol. 11, p103Background: Glutamate is the principal excitatory neurotransmitter in the central nervous system which acts by the activation of either ionotropic (AMPA, NMDA and kainate receptors) or G-protein coupled metabotropic receptors. Glutamate is widely accepted to play a major role in the path...
- Attitudes Toward Everyday Odors for Children with Visual Impairments: A Pilot Study.
Ferdenzi, Camille; Coureaud, G�rard; Camos, Val�rie; Schaal, Benoist // Journal of Visual Impairment & Blindness; Jan2010, Vol. 104 Issue 1, p55The article presents information on a pilot study which investigated the self-reported awareness and reactivity to odors of children with visual impairments and sighted children. The study population of six boys and two girls with visual impairments, aged 8 to 11, recruited from a specialized...
- The evolutionary history of the SAL1 gene family in eutherian mammals.
Meslin, Camille; Brimau, Fanny; Meillour, Patricia Nagnan-Le; Callebaut, Isabelle; Pascal, G�raldine; Monget, Philippe // BMC Evolutionary Biology; 2011, Vol. 11 Issue 1, p148Background: SAL1 (salivary lipocalin) is a member of the OBP (Odorant Binding Protein) family and is involved in chemical sexual communication in pig. SAL1 and its relatives may be involved in pheromone and olfactory receptor binding and in pre-mating behaviour. The evolutionary history and the...
- Research Highlights.
Aranda, Victoria; Da Silva, Kevin; Kushnir, Anna; L�pez, Juan Carlos; Schubert, Charlotte; Wenner, Melinda // Nature Medicine; Jan2010, Vol. 16 Issue 1, p42The article presents the highlights of research on several diseases. A new study show that tumor change the composition of the extracellular matrix (ECM) transforming a soft barrier of collagen to a hard surface. Chemotherapy for acute myeloid leukemia (AML) commonly decreases lymphocytopenia,...
- Dynamic development of the first synapse impinging on adult-born neurons in the olfactory bulb circuit.
Aranda, Victoria; Da Silva, Kevin; Kushnir, Anna; L�pez, Juan Carlos; Schubert, Charlotte; Wenner, Melinda // Neural Systems & Circuits; 2011, Vol. 1 Issue 1, p1The article offers information on a neuroscience research that examines the synaptic events related to the formation and maturation of the first glutamatergic synapses on adult-born granule cells (GCs), subtypes of olfactory bulb (OB) neurons. It is mentioned that OB integrates newborn...
- On the Origin and Evolution of Vertebrate Olfactory Receptor Genes: Comparative Genome Analysis Among 23 Chordate Species.
Niimura, Yoshihito // Genome Biology & Evolution; Jan2009, Vol. 2009, p34Olfaction is a primitive sense in organisms. Both vertebrates and insects have receptors for detecting odor molecules in the environment, but the evolutionary origins of these genes are different. Among studied vertebrates, mammals have ~1,000 olfactory receptor (OR) genes, whereas teleost...
- Computational Biology of Olfactory Receptors.
Crasto, Chiquito J. // Current Bioinformatics; Jan2009, Vol. 4 Issue 1, p8Olfactory receptors, in addition to being involved in first step of the physiological processes that leads to olfaction, occupy an important place in mammalian genomes. ORs constitute super families in these genomes. Elucidating olfactory receptor function at a molecular level can be aided by a...
- "EFFECTIVE MICROORGANISMS" (EM) IN REDUCING NOXIOUSNESS OF SELECTED ODORANT SOURCES.
Kulig, Andrzej; Barczak, Radoslaw // Environment Protection Engineering; 2010, Vol. 36 Issue 1, p13The article presents the changes in a chemical quality of air and in the olfactory noxiousness levels caused by the application of Effective Microorganisms (EM) contained in the EM-Farming� preparation. The preparation was applied in selected facilities considered to be substantial sources of...
- Putative Chemosensory Receptors of the Codling Moth, Cydia pomonella, Identified by Antennal Transcriptome Analysis.
Bengtsson, Jonas M.; Trona, Federica; Montagn�, Nicolas; Anfora, Gianfranco; Ignell, Rickard; Witzgall, Peter; Jacquin-Joly, Emmanuelle // PLoS ONE; Feb2012, Vol. 7 Issue 2, p1The codling moth, Cydia pomonella, is an important fruit pest worldwide. As nocturnal animals, adults depend to a large extent on olfactory cues for detection of food and mates, and, for females, oviposition sites. In insects, odor detection is mediated by odorant receptors (ORs) and ionotropic...
- Two Odorant-Binding Proteins Mediate the Behavioural Response of Aphids to the Alarm Pheromone (E)-�arnesene and Structural Analogues.
Yu Feng Sun; De Biasio, Filomena; Hui Li Qiao; Iovinella, Immacolata; Shao Xiang Yang; Yun Ling; Riviello, Lea; Battaglia, Donatella; Falabella, Patrizia; Xin Ling Yang; Pelosi, Paolo // PLoS ONE; Mar2012, Vol. 7 Issue 3, p1Background: Aphids are agricultural pests of great economical interest. Alternatives to insecticides, using semiochemicals, are of difficult applications. In fact, sex pheromones are of little use as aphids reproduce partenogenetically most of the time. Besides, the alarm pheromone,...
- Learning about the Functions of the Olfactory System from People without a Sense of Smell.
Croy, Ilona; Negoias, Simona; Novakova, Lenka; Landis, Basile N.; Hummel, Thomas // PLoS ONE; Mar2012, Vol. 7 Issue 3, p1The olfactory system provides numerous functions to humans, influencing ingestive behavior, awareness of environmental hazards and social communication. Approximately 1/5 of the general population exhibit an impaired sense of smell. However, in contrast to the many affected, only few patients...
- Functional Analysis of General Odorant Binding Protein 2 from the Meadow Moth, Loxostege sticticalis L. (Lepidoptera: Pyralidae).
Jiao Yin; Honglin Feng; Hongyan Sun; Jinghui Xi; Yazhong Cao; Kebin LI // PLoS ONE; Mar2012, Vol. 7 Issue 3, p1Odorant binding proteins play a crucial role in transporting semiochemicals across the sensillum lymph to olfactory receptors within the insect antennal sensilla. In this study, the general odorant binding protein 2 gene was cloned from the antennae of Loxostege sticticalis, using reverse...
- Differential Patterns of Food Appreciation during Consumption of a Simple Food in Congenitally Anosmic Individuals: An Explorative Study.
Novakova, Lenka; Bojanowski, Viola; Havl�cek, Jan; Croy, Ilona // PLoS ONE; Apr2012, Vol. 7 Issue 4, p1Food is evaluated for various attributes. One of the key food evaluation domains is hedonicity. As food is consumed, its hedonic valence decreases (due to prolonged sensory stimulation) and hedonic habituation results. The aim of the present study was to investigate changes in food pleasantness...
