Citations with the tag: MEDICAL genetics
Results 1 - 50
- Helping sick kids, tracing drugs.
Lewis, Ricki // FDA Consumer; Mar1993, Vol. 27 Issue 2, p23Part II. Discusses diagnostic test kits that use monoclonal antibody technology to detect drugs of abuse and DNA probes to diagnose infections. How monoclonal (MAb) tests are one in an array of medical devices made possible by biotechnology to detect diseases; How MAbs are pure preparations of...
- New creations?
Lewis, Ricki // Hastings Center Report; Jan/Feb91, Vol. 21 Issue 1, p32Discusses the use of embryonic stem cells (ES cells) to create new genetic strains of animals. Questions whether or not it is ethical for research using ES cells to proceed, given the effects of the research on the animals involved and the potential implications for future research. ...
- Cart before the horse.
Lewis, Ricki // Hastings Center Report; Jul/Aug97, Vol. 27 Issue 4, p48Focuses on a study published in the `New England Journal of Medicine,' on physicians' readiness for genetic tests.
- What do you know about your family's medical history.
E.B. // Medical Update; Mar98, Vol. 21 Issue 9, p3Focuses on the importance of knowing the family's medical history in the management of medical genetics. Implications in the prevention and treatment of diseases; Advances in medical genetics; Possibility of late development for genetic diseases; Analysis of the preimplantation genetic...
- Sick policemen help to pinpoint arthritis gene.
E.B. // New Scientist; 3/21/92, Vol. 133 Issue 1813, p15Reports on a study by researchers at the University of Toronto that has found a link between Reiter's syndrome and bacterial infections. Study of 470 police officers that were struck with food poisoning; Researchers pinpointed a gene called HLA-B 27 as the predisposing factor; Two ways to...
- What's wrong with this patient?
Hagen, Kathryn; O'Connor, Eileen // RN; Feb93, Vol. 56 Issue 2, p34Features the Ehlers-Danlos syndrome (EDS), a genetic connective tissue disorder. Cause; Distinction from lupus; Incidence rate; Known types; Diagnosis; Management and interventions; Emotional toll on the afflicted persons.
- Better genetic testing for rare syndrome.
Hagen, Kathryn; O'Connor, Eileen // Nutrition Health Review: The Consumer's Medical Journal; 1992, Issue 63, p10Reports that a new and better genetic test has been developed for Prader-Willi syndrome (PWS). What PWS is; Array of sophisticated molecular techniques used; How a missing segment of a particular chromosome leads to the disease; Identification of most PWS victims through a blood test; Research...
- Praying for a miracle.
Hagen, Kathryn; O'Connor, Eileen // Redbook; Aug89, Vol. 173 Issue 4, p104Discusses the lives of three young boys who are afflicted with genetic defects. Genetic research; Prenatal testing; Hope for the future. INSET: `It's terrible to live like this-terrible for him and us.'..
- Medical genetics gets boost in India.
Mudur, Meenal // BMJ: British Medical Journal (International Edition); 8/26/95, Vol. 311 Issue 7004, p529Reports on the Indian government's focus on the development of skills in human genetics and its plan to use data from the international human genome project for medical use. Allotment of four million pounds for the program; Spread of the availability of prenatal diagnosis of genetic disorders...
- Medical genetics.
Yates, John R.W. // BMJ: British Medical Journal (International Edition); 4/20/96, Vol. 312 Issue 7037, p1021Focuses on advances in medical genetics. Genome research in 1995; Identification of genes for most common single gene disorders and cancer susceptibility genes; Diseases resulting from interactions between genes and the environment; Technologies used in cytogenetics laboratories. INSETS:...
- Diseases that hark back to Stone Age lifestyle.
Miller, Susan Katz // New Scientist; 2/27/93, Vol. 137 Issue 1862, p10Reports on a meeting of proponents of the emerging field of evolutionary medicine held at the American Association for the Advancement of Science meeting in Boston. What evolutionary medicine is based on; How it may shed light on congestive heart failure; How it can be used to explain the rise...
- Anticipating disease.
Miller, Susan Katz // New Scientist; 5/22/93, Vol. 138 Issue 1874, p38Discusses anticipation or the tendency of certain genetic diseases to occasionally become more severe as they are passed from one generation to the next. Fragile X syndrome, a common form of inherited mental retardation; Huntington's disease.
- Genetic disease.
Miller, Susan Katz // Mayo Clinic Health Letter; Jan1996, Vol. 14 Issue 1, p1Reports on developments in the research on the origins of illness. Significance of genetic code in the study of diseases; Diseases with single or multiple genetic links; Potential of gene therapy in the treatment of genetic diseases.
- `Spelling errors' can be deadly.
Miller, Susan Katz // Mayo Clinic Health Letter; Oct1992, Vol. 10 Issue 10, p6Looks at how genetic defects are like spelling errors, even a small change can garble a gene's instructions. Cystic fibrosis as an example; What DNA consists of; How scientists can read the genetic code; How this could lead to better treatment for cystic fibrosis by inserting a `good' gene, or...
- UK to regulate 'serious' genetic tests.
Mitchell, Peter // Nature Medicine; Mar2003, Vol. 9 Issue 3, p250Reports that direct-to-consumer marketing of genetic testing services in Great Britain is likely to be regulated under proposals by the government-appointed Human Genetics Commission. Human Genetics Alert's criticism of the commission.
- Call to plan now for cancer gene screening.
Mitchell, Peter // New Scientist; 2/6/93, Vol. 137 Issue 1859, p5Reports on the warning by the head of the United States Human Genome Project, Francis Collins, of the need to prepare for mass screening for genetic diseases. Problems Collins wants to avoid; Pilot screening program set up for cystic fibrosis.
- Jumping genes pave the way to safer therapy.
Coghlan, Andy // New Scientist; 3/18/95, Vol. 145 Issue 1969, p16Reports on the future use of jumping genes in persons with genetic diseases. Information on inserting genes into patients; Work by Suzanne Sandmeyer and her colleagues at the University of California, Irvine.
- The case of the sour Englishman.
Westfall, S. // Health (Time Inc. Health); Apr92, Vol. 6 Issue 2, p32Tells the story of a man who discovered he had hereditary fructose intolerance, a genetic disorder in which the person is lacking an enzyme needed to turn fructose, or `fruit sugar,' into glucose, the sugar that the body uses. About one in 20,000 has hereditary fructose intolerance; The...
- The assurances of genes.
Brownlee, S.; Silberner, J. // U.S. News & World Report; 7/23/90, Vol. 109 Issue 4, p57Considers the effects of genetic testing to predict disease, a new technology that may revolutionize the insurance industry which might be tempted to discriminate against the `healthy ill,' people who are not yet sick but carry genetic traits predisposing them to future illness. INSET: The...
- First experiment approved.
Gershon, D. // Nature; 8/2/1990, Vol. 346 Issue 6283, p402Reports that the National Institutes of Health Recombinant DNA Advisory Committee has been convinced to allow the first human gene therapy experiment. Summary of other new proposals awaiting review.
- Genetic homogeneity between acute and chronic forms of spinal muscular atrophy.
Gilliam, T.C.; Brzustowicz, L.M. // Nature; 6/28/1990, Vol. 345 Issue 6278, p823Presents the typing of four inbred acute-spinal muscular atrophy families with DNA markers on chromosome 5q. Methods; Results; Discussion.
- Penetrating the peroxisome.
Valle, David; Gartner, Jutta // Nature; 2/25/1993, Vol. 361 Issue 6414, p682Notes that over the past twelve months the molecular disciples of Sir Archibald Garrod have invaded the world of peroxisomes, indentifying three genes involved in inborn errors of peroxisomal function. Peroxisomes as single, membrane-bound organelles present in nearly all eukaryotic cells;...
- Closing the Menkes disease gene.
Davies, Kevin // Nature; 1/7/1993, Vol. 361 Issue 6407, p98Comments on the isolation of the gene responsible for the X-linked Menkes disease, heralding great promise for our understanding of copper metabolism and for diagnosis of the disorder. Predicted structure of the Menkes disease protein; Jane Gitschier and Seymour Packman; Anthony Monaco; Thomas...
- Did radicals strike Lou Gehrig?
McNamara, James O.; Fridovich, Irwin // Nature; 3/4/1993, Vol. 362 Issue 6415, p20Comments on a study by Daniel R. Rosen et al published in `Nature,' 3/4/93, demonstrating that a familial variant of amyotrophic lateral sclerosis (ALS) is linked to defects in the SOD1 gene, which encodes the cytosolic superoxide dismutase (SOD). Studies of Escherichia coli; Candidate receptor...
- Damage-limitation exercises.
Barnes, Deborah E. // Nature; 9/3/1992, Vol. 359 Issue 6390, p12Focuses on certain rare genetic diseases, characterized by cellular hypersensitivity to DNA damage, that confer an increased risk of cancer on people afflicted by them. Announcement of the cloning of complementary DNAs that correct the cellular defect in Fanconi's anemia; Obstacles to the...
- A step closer to helping Lorenzo.
Barnes, Deborah E. // Newsweek; 3/8/1993, Vol. 121 Issue 10, p67Reports that scientists in Paris and Baltimore say they have found a gene that causes adrenoleukodystrophy (ALD), a disease that leads to mental deterioration. Discovery was a surprise; Researchers had suspected only a defective enzyme; Now they think the gene actually causes the enzyme to...
- When DNA isn't destiny.
Begley, Sharon; Glick, Daniel // Newsweek; 12/6/1993, Vol. 122 Issue 23, p53Claims that a bad gene isn't always a death sentence. The discovery that having a gene may be necessary, but not sufficient, for developing a disease; Report by the Institute of Medicine of the National Academy of Sciences concluding that `genetic tests are seldom perfect predictors of (health)...
- Genomics Discoveries Challenge Clinical Research.
Wechsler, Jill // Applied Clinical Trials; Apr2001, Vol. 10 Issue 4, p24Focuses on the impact of advances in genomics on pharmaceutical research in the United States. Breakthroughs in the research on the human genome sequence; Potential use of information about the human genome in the development of new therapies; Scope of research and development strategies for...
- Economic Implications of the Human Genome Project.
Elrod-Erickson, Matthew J.; Ford, William F. // Business Economics; Oct2000, Vol. 35 Issue 4, p57Examines the future impact of the human genome project (HGP) on the world economy. Main benefits from the HGP; Status of the HGP as of September 2000; Genetic techniques.
- Hitachi's 'Hitagene'--a major advance in pinpointing disease.
Elrod-Erickson, Matthew J.; Ford, William F. // Life Science Today; Apr/May2002, Vol. 3 Issue 2, p8Reports the development of a gene hunting software useful for detecting diseases called Hitagene by researchers at Hitatchi Dublin Laboratory of Trinity College in Dublin, Ireland. Details of the speed of the software in identifying genetic causes of diseases; Application of the linkage...
- Distinctive Facies Suggest Bartter Syndrome.
Elrod-Erickson, Matthew J.; Ford, William F. // Kidney; Jan/Feb98, Vol. 7 Issue 1, p15Investigates whether distinctive facies suggest Bartter syndrome (BS) in a cohort of 20 cases in Costa Rica. Clinical characterization of the disease condition; Importance of determining whether phenotypic difference indicate genetic heterogeneity in BS.
- A genetics primer for primary care.
Elrod-Erickson, Matthew J.; Ford, William F. // Patient Care; 11/15/1998, Vol. 32 Issue 18, p22Explains several concepts upon which genetic medicine is based. Look at the history of genetics; Basis of genetics in biochemistry; Central dogma of molecular biology explaining the transcription of DNA to RNA; Composition of the genetic code; Mutations found in human DNA; Elucidation of...
- Clinical applications of molecular medicine.
Elrod-Erickson, Matthew J.; Ford, William F. // Patient Care; 11/15/1998, Vol. 32 Issue 18, p86Explains several issues surrounding the clinical application of gene therapy on humans. Central challenge to the success in human gene therapy; Vectors or gene delivery vehicles; Genetic-deficiency diseases that are target for gene therapy; Intense interest in the use of gene therapy to treat...
- Ethical concerns and the future of gene therapy.
Elrod-Erickson, Matthew J.; Ford, William F. // Patient Care; 11/15/1998, Vol. 32 Issue 18, p88Analyzes the ethical concerns associated with the clinical application of gene therapy on humans. Acceptability of using somatic cell gene therapy of the fetus in the utero; Look at the application of gene therapy in nonmedical uses; Scientific and technical developments needed for the approval...
- Ethical issues in the age of genetics.
Elrod-Erickson, Matthew J.; Ford, William F. // Patient Care; 11/15/1998, Vol. 32 Issue 18, p137Looks at the ethical considerations confronting physicians in the issue of genetic information. Predictive quality of genetic information; Ambiguous concept of genetic disease; Implication of genetic information on biological relatives; Physician's role and responsibilities in genetics...
- About SEQUENOM.
Elrod-Erickson, Matthew J.; Ford, William F. // Biotech Business; Nov2003, Vol. 16 Issue 11, p5Provides information on the genetics company SEQUENOM Inc..
- What's lurking in your family tree?
Elrod-Erickson, Matthew J.; Ford, William F. // Consumer Reports on Health; Sep92, Vol. 4 Issue 9, p65Discusses the importance of knowing your family history. Results of a recent study of medical records for nearly 9000 patients; How knowing your family history can save your life; When genes tell the main story; Inheriting the common killers; How to figure out whether a disease that appears in...
- Genetic testing: Do you really want to know?
Lipman, Marvin M. // Consumer Reports on Health; Sep99, Vol. 11 Issue 9, p11Discusses the benefits and drawbacks of genetic counseling.
- Genetics: An explosion of knowledge is transforming clinical practice.
COLLINS, FRANCIS S. // Geriatrics; Jan99, Vol. 54 Issue 1, p41Explores the clinical applications of genetic medicine. Discussion on the human genome; Diseases that were diagnosed by genetics; Clinical applications of gene discovery; Concerns about genetic revolution.
- Molecular genetic approaches to understanding disease.
Savill, John // BMJ: British Medical Journal (International Edition); 01/11/97, Vol. 314 Issue 7074, p126Part II. Examines the use of molecular genetic approaches to understand diseases. Discovering the gene responsible for a disease; Xenografting through transgenesis; Gene transfer and gene therapy.
- Continuing increase in incidence of childhood-onset type 1 diabetes in the Czech Republic 1990�2001.
Cinek, Ondrej; Sumnik, Zdenek; Vavrinec, Jan // European Journal of Pediatrics; 2003, Vol. 162 Issue 6, p428Cites a study conducted by the authors on the continuing increase in incidence of childhood-onset type 1 diabetes in the Czech Republic, during 1990-2001. Rise in incident rates of type 1 diabetes in Eastern and Central European populations; Impact of gender and body mass index on the onset of...
- Genes and agents: How to prioritize to prevent disease.
Rylander, Ragnar // Archives of Environmental Health; Sep/Oct95, Vol. 50 Issue 5, p333Editorial. Asserts that information on DNA mutations, genetic predisposition and mechanisms for tumor development should be made available for an understanding of the basis for disease. Identification of at-risk individuals for prevention and tre atment purposes; Developments in the study of...
- SNPs: Can Genetic Variants Control Cancer Susceptibility?
Webb, Tracy // JNCI: Journal of the National Cancer Institute; 4/3/2002, Vol. 94 Issue 7, p476Examines the association of disease risk with the inheritance of specific genetic variants in the U.S. Definition of single nucleotide polymorphism (SNP); Protection of cells from deleterious mutations by repairing damaged DNA; Approaches used to identify SNP associated with increased cancer risk.
- Could drugs give proteins a quick fix?
Cohen, Philip // New Scientist; 04/19/97, Vol. 154 Issue 2078, p18Reports on the ability of certain compounds to fix proteins caused by defective genes. Implications in the use of simple chemicals in treating genetic diseases; Comparison with advanced gene therapy; Causes of certain genetic diseases.
- Genetics in medicine: The future is here.
Korf, Bruce R. // Patient Care; 11/15/1998, Vol. 32 Issue 18, p7Editorial. Encourages the American public to update their knowledge about the technological advances in human medical genetics. Requirement of educational efforts at all school levels concerning the advances in genetics; Overall impact of genetics on the day-to-day practice of medicine; Public...
- Genetic sources of individual differences in the cerebellum.
Airey, David C; Lu, Lu; Shou, Siming; Williams, Robert W // Cerebellum; Dec2002, Vol. 1 Issue 4, p233The highly regular anatomy of the cerebellum that results from myriad genetic, environmental, and stochastic events during pre- and postnatal development is nonetheless quantitatively very different among individuals. Understanding the sources of these individual differences represents an...
- Response by Gwen Anderson, Shriver Center for Mental Retardation, Waltham MA, USA.
Airey, David C; Lu, Lu; Shou, Siming; Williams, Robert W // Nursing Ethics; May99, Vol. 6 Issue 3, p254Comments on harm created by highly specialized, fragmented and competitive model of delivering prenatal services to patients and their families. Interdisciplinary model of delivering genetics services; Advocacy as a rights-based concept.
- Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy .
Hochhaus, A.; Kreil, S.; Corbin, A.S.; La Rosee, P.; Cross, N.C.P.; Berger, U.; Gschaidmeier, H.; Hehlmann, R. // Leukemia (08876924); Nov2002, Vol. 16 Issue 11, p2190Explores the molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy. Selective inhibition of the BCR-ABL tyrosine kinase by imatinib in patients with chronic myelogenous leukemia (CML); Description of CML; Most common mechanisms of relapse.
- Redearchers gene test differentiates breast cancer types.
Hochhaus, A.; Kreil, S.; Corbin, A.S.; La Rosee, P.; Cross, N.C.P.; Berger, U.; Gschaidmeier, H.; Hehlmann, R. // Hudson Valley Business Journal; 03/12/2001-03/19/2001, Vol. 11 Issue 26, p21Focuses on the genetic test that can easily distinguish between hereditary and sporadic forms of breast cancer, developed by the National Genome Research Institute. Capability of doctors to diagnose the cause of the disease and guide treatment decisions; Details of the diagnostic procedure;...
- Outsmart the 'Fat Gene.'
Harrar, Sari // Prevention; May2001, Vol. 53 Issue 5, p42Discusses how the so-called thrifty gene, known as G protein B3 subunit 825 TT, is an inherited gene which can cause people to gain weight.
