Citations with the tag: GRIGNARD reagents
Results 1 - 50
- Reaction of 4-aryl-2,6-dichlorobenzo[ e[1,2]oxaphosphinine 2-oxides with organomagnesium compounds as a convenient synthetic approach to ( Z)-dialkyl(aryl)[2-(2-hydroxyaryl)-2-arylethenyl]phosphine oxides.
Tatarinov, D. A.; Mironov, V. F.; Varaksina, E. N.; Konovalov, A. I. // Russian Journal of General Chemistry; Jun2008, Vol. 78 Issue 6, p1287
A letter to the editor is presented regarding the mechanism and products formed by the reaction of 4-aryl-2,6-dichlorobenzo[e][1,2]oxaphosphinine 2-oxides I with organomagnesium reagents (Grignard reagents).
- Grignard reaction.
Tatarinov, D. A.; Mironov, V. F.; Varaksina, E. N.; Konovalov, A. I. // Taber's Cyclopedic Medical Dictionary (2009); 2009, Issue 21, p987
An encyclopedia entry for "Grignard reaction," which refers to a classical organic-chemical process forming carbon-carbon bonds, is presented.
- Iron-Catalyzed Cross-Coupling Reaction of Aryl Grignard Reagents with bis(2-bromovinyl)benzenes.
Operamolla, Alessandra; Omar, Omar Hassan; Babudri, Francesco; Vitulli, Michele; Farinola, Gianluca M. // Letters in Organic Chemistry; Oct2009, Vol. 6 Issue 7, p573
Fe(acac)3 has been used as the catalyst in cross-coupling reactions of aryl Grignard reagents with 1,4-bis(2-bromovinyl)benzenes affording bis(2-arylvinyl)benzenes. Effects of alkoxy substituents on both reactants and of the temperature on the reaction outcome are investigated.
- Cyclomagnesiation of nitrogen-containing 1,2-dienes with grignard compounds catalyzed by CpTiCl.
D'yakonov, V.; Makarov, A.; Makarova, E.; Khalilov, L.; Dzhemilev, U. // Russian Journal of Organic Chemistry; Mar2012, Vol. 48 Issue 3, p349
Cyclomagnesiation of nitrogen-containing 1,2-dienes with Grignard compounds in the presence of activated magnesium and CpTiCl as catalyst afforded 2,5-bis(aminoalkylidene)magnesacyclopentanes in high yield.
- Starting small-scale Grignard reactions.
Hodges, Ray // Chemistry in Australia; Feb2012, Vol. 79 Issue 1, p30
The article discusses small-scale Grignard reactions, wherein all reagents are dry and the approach includes elaborate methods for keeping all components free of water. In a typical exercise, the Grignard reagent is made by dissolving 2.5 grams of magnesium turnings in a solution of bromobenzene...
- Synthetic dyes: simple and original ways to 4-substituted flavylium salts and their corresponding vitisin derivatives.
Roehri-Stoeckel, Christine; Gonzalez, Emmanuel; Fougerousse, Andr�; Brouillard, Raymond // Canadian Journal of Chemistry; Jul2001, Vol. 79 Issue 7, p1173
Flavylium salts substituted at the 4-position have been prepared according to a Grignard reaction of some flavones with appropriate alkyl- and aryl-magnesium bromides. Among these compounds, 4-methyl flavylium salts were gently reacted with aromatic aldehydes, affording new anthocyanidin...
- The addition of organometallic reagents to tetramesityldigermene.
Fujdala, Kyle L; Gracey, David W.K; Wong, Erica F; Baines, Kim M // Canadian Journal of Chemistry; Nov2002, Vol. 80 Issue 11, p1387
The thermolysis and photolysis of hexamesitylcyclotrigermane in the presence of ethylmagnesium bromide has been investigated. Under photochemical conditions, ethyldimesitylgermane, 1,2-diethyl-1,1,2-trimesityldigermane and ethyl-1,1,2,2-tetramesityldigermane were isolated and, under thermal...
- Stereospecific Grignard reactions of cholesteryl 1-alkenesulfinate esters: Application of the Andersen Protocol to the preparation of non-racemic a,�-unsaturated sulfoxides.
Strickler, Rick R; Motto, John M; Humber, Craig C; Schwan, Adrian L // Canadian Journal of Chemistry; Jun2003, Vol. 81 Issue 6, p423
Enantiomerically enriched a,�-unsaturated sulfinate esters of (�)-cholesterol undergo stereospecific substitutions at sulfur when treated in benzene at 6�C with Grignard reagents. Sulfoxides with ees of 85�99.5% are obtained when enantiopure sulfinates are used. The substitution...
- Cluster quantum-chemical study of Grignard reagent formation.
Porsev, V.; Tulub, A. // Doklady Physical Chemistry; Aug2006, Vol. 409 Issue 2, p237
This article discusses the Grignard reaction which is the most widely used reactions in synthetic organic chemistry. It identifies the two-stage process of Grignard formation reaction. The first stage involves the formation of alkylmagnesium halide adsorbed on the magnesium cluster, and the...
- Copper-catalyzed cross-coupling of ( Z)-allyl phenyl ethers with Grignard compounds in the synthesis of insect pheromones.
Petrushkina, E. A.; Kalinin, V. N. // Russian Journal of General Chemistry; Oct2008, Vol. 78 Issue 10, p1897
(8 Z)-Dodec-8-en-1-yl acetate (pheromone of oriental fruit moth Grapholita molesta) and (9 Z)-dodec-9-en-1-yl acetate (pheromone of grape berry moth Paralobesia viteana) containing impurities of isomeric structures were synthesized via copper-catalyzed cross-coupling of ( Z)-1-phenoxyhex-2-ene...
- Interaction of (1-phenylethyl)indole-2-carbonitrile with C-nucleophiles.
Golantsov, N.; Karchava, A.; Yurovskaya, M. // Chemistry of Heterocyclic Compounds; Aug2006, Vol. 42 Issue 8, p1021
Methods of obtaining ketones and enamino esters have been developed on the basis of reactions of 1-(1-phenylethyl)indole-2-carbonitrile with organomagnesium and organozinc compounds. Removal of a benzyl group from the indole nitrogen atom by the Grignard reagent has been discovered.
- Nitropyridines: III. Synthesis of meta-terphenyls by recyclization of nitropyridinium salts.
Sagitullina, G. P.; Glidzinskaya, L. V.; Sagitullin, R. S. // Russian Journal of Organic Chemistry; Aug2006, Vol. 42 Issue 8, p1203
A two-component Hantzsch synthesis was applied to preparation of nitropyridines and their quaternary salts from various enamines and chalcones based on nitroacetophenone. The recyclization of nitropyridinium quaternary salts under the treatment with an aqueous-alcoholic alkali led to preparation...
- Synthesis of 3-(4-bromophenyl)-1-morpholino-2-phenylalkan-3-ol hydrochlorides.
Isakhanyan, A. U.; Gevorgyan, G. A.; Panosyan, G. A. // Russian Journal of Organic Chemistry; Aug2008, Vol. 44 Issue 8, p1161
Reactions of 1-(4-bromophenyl)-3-morpholino-2-phenylpropan-1-one with various Grignard compounds in diethyl ether gave a broad series of tertiary amino alcohols, 3-(4-bromophenyl)-1-morpholino-2-phenylalkan-3-ol hydrochlorides, that can be regarded as Trihexyphenidyl analogs.
- Simple and Convenient Synthesis of (�)-Bakuchiol.
Hongli Chen; Yuanchao Li // Letters in Organic Chemistry; Sep2008, Vol. 5 Issue 6, p467
A simple and convenient synthesis of (�)-bakuchiol has been developed. The key intermediate was obtained in only one step from the easily available starting material, citral, by an 1,4-addition procedure. (�)-Bakuchiol was finally produced in 4 steps to give 50% overall yield.
- Allyl Silane Additions to Highly Electrophilic 5,6-Dihydro-2H-1,4-oxazinones.
Shafer, Cynthia M.; Pigza, Julie; Molinski, Tadeusz F. // Letters in Organic Chemistry; Apr2009, Vol. 6 Issue 3, p224
Allylsilane addition to the dihydro-2H-1,4-oxazinones, 1, proceeded in moderate to good yields with transdiastereoselectivity. The yield of addition reactions of 5-phenyl-5,6-dihydro-2H-1,4-oxazin-2-one with allylsilanes is improved over the corresponding additions of Grignard reagents to 1 and...
- Synthesis of 2-hydroxy-5-methyl-3-hexanone.
Tian, Hong-Yu; Ye, Hong-Lin; Sun, Bao-Guo; Wang, Ya-Ling // Journal of Chemical Research; 2011, Vol. 35 Issue 1, p51
2-Hydroxy-5-methyl-3-hexanone, which is a characteristic component of eucalyptus honeys, was synthesised by oxidation of the silyl enol ether of 5-methyl-3-hexanone. 5-Methyl-3-hexanone was prepared by Grignard reaction and oxidation starting from isovaleraldehyde and ethylmagnesium bromide. The...
- Synthesis of 2,4-diarylquinolines: nickel-catalysed ligand-free cross-couplings of 4-chloro-2-arylquinolines with arylmagnesium halides in 2-methyltetrahydrofuran.
Li, Zhenhua; Xu, Lingmin; Su, Weike // Journal of Chemical Research; 2011, Vol. 35 Issue 4, p240
A ligand-free and room temperature protocol for the synthesis of 2,4-diarylquinolines is described. Treatment of 4-chloro-2-arylquinolines with arylmagnesium halides in the presence of a catalytic amount of nickel(II) chloride without ligands in 2-methyltetrahydrofuran (2-MeTHF) afforded the...
- Hexatriene formation from the regiospecific alkene cross-metathesis of trans-1-(buta-1,3-dien-1-yl)-2-acryloyloxynaphthalene.
Gabbutt, Christopher D.; Heron, B. Mark; Kilner, Colin; Kolla, Suresh B. // Journal of Chemical Research; 2011, Vol. 35 Issue 9, p531
Wittig olefination of 2-hydroxy-1-naphthaldehyde with allylidenetriphenylphosphorane afforded trans-1-(buta-1,3-dien-1-yl)-2-naphthol in good yield. Subsequent O-acylation with acryloyl chloride provided the corresponding acrylate ester. Attempts to effect cyclisation of the latter by...
- Synthesis by Ring-Closing Metathesis and Cytotoxic Evaluation of Novel Thienylmacrolactones.
Krauss, J�rgen; K�bler, Daniela; Miller, Verena; Bracher, Franz // Scientia Pharmaceutica; Mar2012, Vol. 80 Issue 1, p29
This paper describes the synthesis and biological evaluation of macrolactones containing a thienyl substituent as simple analogues of epothilones. The compounds were prepared in a brief and efficient manner from thiophene-2- carbaldehyde using a ring-closing metathesis with Grubbs I or Grubbs II...
- Calorimetric Insight into Coupling between Functionalized Primary Alkyl Halide and Vinylic Organocuprate Reagent: Experimental Determination of Reaction Enthalpies in the Synthesis of (R)-Ethyl 3-(tert-butyldimethylsilyloxy) hex-5-enoate -- a Key...
Casar, Zdenko; Tram�ek, Marko; Gor�ek, Andreja // Acta Chimica Slovenica; 2010, Vol. 57 Issue 1, p66
The first calorimetric study of coupling between organocuprate, derived from Grignard reagent (vinyl magnesium chloride), and primary alkyl halide (e.g. (S)-ethyl 3-(tert-butyldimethylsilyloxy)-4-iodobutanoate) has been conducted. This transformation is paramountly important for efficient...
- On direct iron-catalyzed cross-coupling reactions.
Czaplik, Waldemar Maximilian; Mayer, Matthias; Grupe, Sabine; von Wangelin, Axel Jacobi // Pure & Applied Chemistry; Jul2010, Vol. 82 Issue 7, p1545
A new methodology for the direct cross-coupling reaction between aryl halides and alkyl halides under iron catalysis is described. Unlike conventional protocols, the direct cross-coupling obviates the need for the preformation of stoichiometric amounts of Grignard species and thus exhibits a...
- Synthesis of Substituted 3,4-Dialkyl-2,6-Diaryl-Piperidin-4-ol Derivatives and Their Conformational Study.
Maruthavanan, T.; Venkatesan, P. // E-Journal of Chemistry; 2012, Vol. 9 Issue 2, p1029
The synthesis of series of 3,4-dialkyl-2,6-diaryl-piperidin-4-ol derivatives (7-12) by reduction of cis-3-alkyl-2,6-diarylpiperidin-4-one (1-6) using Grignard reagent has been reported. The synthesized heterocycles have been characterized on basis of spectroscopic data and their conformation has...
- Nickel-catalyzed C(sp)-C(sp) Cross Coupling Reactions of Sulfur-Functionalities and Grignard Reagents.
Someya, Chika; Weidauer, Maik; Enthaler, Stephan // Catalysis Letters; May2013, Vol. 143 Issue 5, p424
In the present study, the nickel-catalyzed carbon carbon bond formation of a range of sulfur containing substrates with Grignard reagents via desulfurization has been explored. After investigation of different reaction parameters with a well-defined nickel complex an excellent and...
- A Novel and Convenient Method for the Synthesis of Ubiquinone-10.
Wang, Feng; Jiang, Xiangrui; Hu, Lihong; Dong, Shengyi; Wu, Xiumei; Bai, Hua; Zhang, Yongmin; Stöckigt, Joachim; Zhao, Yu // Letters in Organic Chemistry; Aug2006, Vol. 3 Issue 8, p610
A novel and convenient synthetic approach to ubiquinone-10 was reported via the SN2'-type nucleophilic displacement reaction between copper-catalyzed Grignard reagent and the secondary allylic acetate, which was suitable for the large-scale production of ubiquinone-10.
- Synthesis of 3-aryl-2-[hydroxy(diaryl)methyl]-4-oxo-3,4-dihydroquinazolines.
Shemchuk, L. A.; Chernykh, V. P.; Levashov, D. V.; Sytnik, K. M. // Russian Journal of Organic Chemistry; Nov2010, Vol. 46 Issue 11, p1687
By heating arylamides of N-ethoxalylanthranilic acid in the acetic acid mediun in the presence of triethylamine the corresponding ethyl 3-aryl-4-oxo-3,4-dihydroquinazoline-2-carboxylates were obtained. The latter in the conditions of the Grignard reaction formed...
- Synthesis of Some Derivatives of Benzophenothiazinone Of Pharmaceutical Interests Via Nickel Catalysed Grignard Couplings.
Onoabedje, E. A.; Ezema, B. E.; Ezema, C. G.; Ugwu, D. I. // Chemical & Process Engineering Research; 2013, Vol. 8, p6
Some derivatives of 6-chlorobenzo[a]phenothiazin-5-one were synthesized via nickel catalyzed Grignard couplings. The parent compound 6-chlorobenzo[a]phenothiazin-5-one was prepared by refluxing a mixture of 2- aminobenzenethiol and 2,3-dichloro-1,4-napthoquinone in anhydrous potassium acetate in...
- Synthesis and Biological Evaluation of Novel Alkyl-Imidazolyl Carbinols and their Esters: Potent Antimycotics.
KRAUSS, Jürgen; GRATZL, Carina; STURM, Verena; MÜLLER, Christoph; STAUDACHER, Verena; SCHMIDT, Christoph Q.; BRACHER, Franz // Scientia Pharmaceutica; 2013, Vol. 81 Issue 3, p641
A novel series of imidazol-5-yl carbinols and their 4-chlorobenzoyl esters has been synthesized by the Grignard reaction and subsequent esterification. These compounds were screened for their antimicrobial activities in an agar diffusion assay. The compounds with C10 to C12-alkyl side chains...
- Synthesis of [9,10-Dihydro-9-(2-methylaminoethyl)-9,10-propanoanthracene].
Al-Saeedi, Adel; Karama, Usama; Farooqui, Mazahar // Asian Journal of Research in Chemistry; Dec2012, Vol. 5 Issue 12, p1460
Reaction of anthrone R1 with Grignard reagent to give 9-substituted anthracene R2 which treatment with α-bromoacroline to give R3. Reaction of R3 with 1M NaOH resulted in transformation into the ring expanded α-hydroxy ketone R4. Transformation of α-hydroxy ketone by using samarium diiodide...
- SYNTHESIS OF THE HYDROCHLORIDES OF 1-(4-ETHOXYPHENYL)-1-ALKYL(ARYL)-2-(4'-CHLOROPHENYL)-3-MORPHOLINOPROPAN-1-OLS.
Gevorgyan, G. A. // Electronic Journal of Natural Sciences; Jul2006, Vol. 2006 Issue 2, p7
α-[4′-Chlorophenyl]-β-morpholino-4-ethoxypropiophenones have been synthesized by aminomethylation of 4-ethoxyphenyl-4′-chlorobenzylketones with paraformaldehyde and morpholine. 1-(4-Ethoxyphenyl)-1-alkyl(aryl)-2-(4′-chlorophenyl)-3-morpholinopropanols were synthesized by interaction of...
- The homocoupling of arylsulfonylhydrazides by palladium-catalysed desulfonation in air.
Zhang, Wei; Zhao, Baoli; Li, Ke // Journal of Chemical Research; Nov2013, Vol. 37 Issue 11, p674
A simple and efficient preparation of biaryl derivatives from arylsulfonyl hydrazides has been developed using Pd(OAc)2 as the catalyst in a mixed solvent of DMA and THF and without the use of any ligand and base.
- Grignard reaction.
Zhang, Wei; Zhao, Baoli; Li, Ke // Taber's Cyclopedic Medical Dictionary; 2005, p910
A definition of the medical term "Grignard reaction" is presented. Grignard reaction refers to a classical organic-chemical process that forms carbon-carbon bonds. It is used to build carbon chains in compounds including drugs, food additives, toxins, and pesticides. The definition is from the...
- Stereoselectivity of Grignard Reaction in the Presence of Chiral Podands and Crown Ethers.
Luk'yanenko, N. G.; Lobach, A. V.; Leus, O. N. // Russian Journal of Organic Chemistry; Feb2004, Vol. 40 Issue 2, p273
Reactions of ethylmagnesium bromide with benzaldehyde and acetophenone in toluene proceed stereoselectively in the presence of catalytic amounts of chiral podands and crown ethers. Under catalytic conditions theyield of the corresponding alcohols is nearly quantitative. The optical yield varies...
- Synthesis of 15�-hydroxyalkyl-substituted (17Z)-pregn-17-enes, their ethers and esters.
Baranovskii, A. V.; Litvinovskaya, R. P.; Khripach, V. A. // Russian Journal of Organic Chemistry; Nov2004, Vol. 40 Issue 11, p1608
Proceeding from ?15-17-ketosteroids via copper(I)-catalyzed 1,4-addition of Grignard reagent followed by modification of the 15-alkenyl substituent, introduction of a 17-ethylidene component via Wittig reaction, and transformations in the A and B rings of the steroid molecule we obtained a...
- (2 E)-4-hydroxyalk-2-enals and 2-substituted furans as products of reactions of (2 E)-4,4-dimethoxybut-2-enal with Grignard compounds.
Garibyan, O. A.; Ovanesyan, A. L.; Makaryan, G. M.; Petrosyan, A. L.; Chobanyan, Zh. A. // Russian Journal of Organic Chemistry; Mar2010, Vol. 46 Issue 3, p406
Methods have been developed for the synthesis of (2 E)-1,1-dimethoxyalk-2-en-4-ols and (2 E)-4-hydroxyalk-2-enals by reaction of (2 E)-4,4-dimethoxybut-2-enals and Grignard compounds. Thermal isomerization of (2 E)-4-hydroxyalk-2-enals gave the corresponding 2-alkylfurans.
- Letters in Organic Chemistry [ Rapid Access to Enantiomerically Pure 3,6-Anhydro-2-deoxy-7-phenylglyconolactones. Synthesis of Diastereoisomers of (+)-Goniofufurone ].
Sartillo-Mel�ndez, Cristhian; Cruz-Gregorio, Silvano; Quintero, Leticia; Sartillo-Piscil, Fernando // Letters in Organic Chemistry; Jul2006, Vol. 3 Issue 7, p504
3,4-Anhydro-2-deoxy-7-phenylglyconolactones were synthesized in six steps from diacetone-Dglucose. Construction of the cis-fused bicyclic systems of the corresponding 3,4-anhydro-2-deoxy-7- phenylglycolactones was achieved by a stereoselective substitution reaction at the anomeric position of...
- Synthesis and antioxidant activity of 1-(4-fluorophenyl)-1-alkyl-2-phenyl-3-morpholinopropan-1-ol hydrochlorides.
Isakhanyan, A.; Gevorgyan, G.; Akopyan, N.; Malakyan, M.; Vardevanyan, L.; Badjinyan, S.; Panosyan, G. // Pharmaceutical Chemistry Journal; Jun2011, Vol. 45 Issue 3, p144
Reactions of 4-fluorophenyl-�-morpholinopropiophenones with various Grignard reagents in anhydrous ether produced new tertiary aminoalcohols, 1-(4-fluorophenyl)-1-alkyl-2-phenyl-3-morpholinopropan-1-ols, that can be regarded as trihexyphenidyl (cyclodol) analogs. The antioxidant properties of...
- Generation of radicals in Grignard reagent formation in the framework of the cluster model.
Porsev, V.; Tulub, A. // Doklady Physical Chemistry; Mar2008, Vol. 419 Issue 1, p53
The article discusses the study of radicals in Grignard reagents which are produced by the reaction of magnesium with organic halide. Though there is no complete understanding of the generation of radicals in the process of the reagent, experiments of the said reagent reaction consisting of the...
- Driving innovation at Halocarbon.
Boswell, Clay // Chemical Market Reporter; 6/5/2006, Vol. 269 Issue 22, p18
The article focuses on the innovations made by Halocarbon Products Corp., a flourocarbon specialist based in New Jersey, in order to produce high-value products. Its recent adoption of Grignard technology shows the importance of custom manufacturing projects in product development and long-term...
- Synthesis of 3-(1-adamantyl)-4-methoxyphenylboric acid.
Tribulovich, V. G.; Garabadzhiu, A. V.; Kalvins, I. // Russian Journal of General Chemistry; Apr2010, Vol. 80 Issue 4, p868
The article discusses the reaction on the synthesis of 3-(1-Adamantyl)-4-methoxyphenylboric acid. It notes that the acid is the key intermediate in the synthesis of active pharmaceutical ingredient (API) 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid (Adapalene). It reveals complete...
- Synthesis of a chiral �-amino acid derivative by a cobalt-catalysed coupling reaction.
Pan, Xianhua; Yu, Wansheng; Ou, Wenhua; Tao, Xiaohu; Wan, Jiaomei; Liu, Feng // Journal of Chemical Research; 2011, Vol. 35 Issue 9, p545
A chiral �-amino acid derivative was synthesised by a cobalt-catalysed alkylation of 2,4,5-trifluorophenyl magnesium bromide with the alkyl halide derivative of L-aspartic acid, using an efficient catalytic reagent: CoCl2/TMEDA. The halide derivative was synthesised from protected L-aspartic...
- Simple synthesis and biological evaluation of flocoumafen and its structural isomers.
Jung, Jae-Chul; Jang, Soyong; Oh, Seikwan; Park, Oee-Sook // Journal of Chemical Sciences; Nov2010, Vol. 122 Issue 6, p833
Simple synthesis and biological properties of flocoumafen 1 and its structural isomers are described. The key synthetic strategies involve Knoevenagel condensation, Grignard reaction, intramolecular ring cyclization and coupling reaction. Flocoumafen 1 was easily separated into cis and trans...
- PREPARATION AND EVALUATION OF 5, 9-DIMETHYL-2-CYCLOPROPYL-2-DECANOL AS A PENETRATION ENHANCER FOR DRUGS THROUGH RAT SKIN.
KHAN, GUL MAJID; HUSSAIN, ABID; HANIF, RAJA MUHAMMAD // Pakistan Journal of Pharmaceutical Sciences; Oct2011, Vol. 24 Issue 4, p451
In the present study a new alcohol derivative of tetrahydrogeraniol (THG), an acyclic monoterpene, has been prepared by using Grignard reagent and methyl cyclopropyl ketone. Penetration enhancing effects of THG and the synthesized derivative 5,9-dimethyl-2-cyclopropyl-2-decanol (DICNOL) on the...
- Synthesis and crystal structure of the chiral �-amino alcohol (S)-a,a-diphenyl-2-pyrrolidine methanol.
Yu-Mei Zhang; Peng Liu; Hong-Li Zhang // Journal of Chemical Research; Nov2010, Vol. 34 Issue 11, p610
Optically pure (S)-a,a-diphenyl-2-pyrrolidine methanol was prepared from L-proline via protection of the amino group, reaction with the Grignard reagents and deprotection of the amino-protected groups in 54.4% yield. The synthetic conditions to prepare (S)-a,a-diphenyl-2-pyrrolidinemethanol were...
- Synthesis, characterization, and non-isothermal curing kinetics of two silicon-containing arylacetylenic monomers.
Tan, Dexin; Shi, Tiejun; Li, Zhong // Research on Chemical Intermediates; Nov2011, Vol. 37 Issue 8, p831
Vinyltri(phenylethynyl)silane ((ph-C=C)-Si-C=CH; VTPES) and phenyltri(phenylethynyl)silane ((ph-C=C)-Si-ph; PTPES) were synthesized by Grignard reaction. Their molecular structures were characterized by means of H NMR, C NMR, Si NMR, and FT-IR spectroscopy. Their nonisothermal thermal curing...
- The Meyers Reaction (1994-2010).
Mortier, Jacques // Current Organic Chemistry; Jul2011, Vol. 15 Issue 14, p2413
No abstract available.
- Mg2H2: New insight on the Mg-Mg bonding and spectroscopic study.
Brites, V.; Guitou, M.; L�onard, C. // Journal of Chemical Physics; 2/7/2011, Vol. 134 Issue 5, p054314
The six dimensional potential energy surface of the electronic ground state X 1Sg+ of Mg2H2 has been generated by the coupled-cluster approach with single, double and perturbative triple excitations [CCSD(T)] combined with the aug-cc-pCVTZ basis set for Mg atoms and the aug-cc-pVTZ basis set for...
- A SIMPLE APPROACH TO SYNTHESIS OF1-PYRIDYLIMIDAZO-[1,5-a] PYRIDINES BY MOLECULAR IODINE.
Parveen, Arshia; Ahmed, Shaikh. K. // International Journal of Pharmaceutical Sciences Review & Resear; Jan/Feb2011, Vol. 6 Issue 1, p38
Molecular iodine catalyzed three component improved procedure for the synthesis of various 1-pyridylimidazo-[1,5-a]pyridines from 1,2-dipyridyl ketone, aromatic aldehydes and ammonium acetate at elevated temperature in excellent isolated yield has been reported. This is a simple and...
- Facile benzannulation of isocoumarins in the efficient synthesis of diversified 1,3-disubstituted isoquinolines.
Manivel, P.; Prabakaran, K.; Nawaz Khan, F.; Jin, Jong // Research on Chemical Intermediates; Feb2012, Vol. 38 Issue 2, p347
An efficient and facile one-pot synthesis of 1,3-disubstituted isoquinolines 3 was accomplished from 3-substituted isocoumarins 1 through diketones, formed in situ via the Grignard reaction, in the presence of ammonium acetate, montmorillonite K-10 catalyst, and ethanol solvent. Graphical...
- Synthesis and biological properties of 1-(4-substituted phenyl)-1-alkyl(aryl)-2-phenyl-3-piperidinopropan-1-ols.
Gasparyan, N.; Vardevanyan, L.; Egiazaryan, D.; Malakyan, M.; Badzhinyan, S.; Avakimyan, D.; Panosyan, G.; Gevorgyan, G. // Pharmaceutical Chemistry Journal; Jul2011, Vol. 45 Issue 4, p224
Interaction of α-phenyl-β-piperidino-4-substituted propiophenones with Grignard reagents in ether was used to synthesize 1-(4-substituted phenyl)-1-alkyl(aryl)-2-phenyl-3-piperidinopropan-1-ols. The antibacterial and antioxidant properties of the aminopropanol hydrochlorides were studied. Some...
- A Novel Iron Complex for Cross-Coupling Reactions of Multiple C-Cl Bonds in Polychlorinated Solvents with Grignard Reagents.
Gartia, Yashraj; Pulla, Sharon; Ramidi, Punnamchandar; Farris, Carolina; Nima, Zeid; Jones, Darin; Biris, Alexandru; Ghosh, Anindya // Catalysis Letters; Nov2012, Vol. 142 Issue 11, p1397
A novel iron(III) complex ( 2) of a pincer ligand [ 1, N2,N6-bis(2,6-diisopropylphenyl)pyridine-2,6-dicarboxamide] was developed and used for remediation of polychlorinated solvents via sp-sp coupling of Grignard reagents with C-Cl bonds. The use of an iron catalyst for such coupling reactions...