Citations with the tag: GRAFT rejection

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• Tough testicles.
   // New Statesman & Society; 10/27/95, Vol. 8 Issue 376, p38 

  Reports on a research by the University of Colorado indicating that transplanted mouse testicles strongly resist rejection by the host.

• Prevention of relapse in pediatric patients with acute leukemias and MDS after allogeneic SCT by early immunotherapy initiated on the basis of increasing mixed chimerism: a single center experience of 12 children.
  Bader, P; Klingebiel, T; Schaudt, A; Theurer-Mainka, U; Handgretinger, R; Lang, P; Niethammer, D; Beck, J F // Leukemia (08876924); Dec99, Vol. 13 Issue 12, p2079 

  The success of allogeneic stem cell transplantation (allo-SCT) in children is mainly affected by relapse or graft rejection. We have recently shown in a study of 55 patients with acute leukemias (ALL 21, AML 20 and MDS 14), that patients who demonstrate increase amounts of autologous marrow...

• IgG Antibodies Indicative of Chronic Rejection.
  Bader, P; Klingebiel, T; Schaudt, A; Theurer-Mainka, U; Handgretinger, R; Lang, P; Niethammer, D; Beck, J F // Kidney; Jan/Feb98, Vol. 7 Issue 1, p29 

  Examines the relevance to chronic rejection of the long-term kinetics of anti-donor antibody in renal transplantation. Mean fluorescent intensity of the anti-donor antibody; Post-transplant production of immunoglobulin G antibody to donor B cells.

• MMF Produces Marked Suppression of Antibody Response to Flu Shot.
  Bader, P; Klingebiel, T; Schaudt, A; Theurer-Mainka, U; Handgretinger, R; Lang, P; Niethammer, D; Beck, J F // Kidney; Jul/Aug98, Vol. 7 Issue 4, p174 

  Presents a summary of the article 'Suppression of the Humoral Immune Response by Mycophenolate Mofetil,' by N.M. Isabel, M.G. Catton et al published in 'Nephrology, Dialysis, Transplantation' periodical.

• RT Can Be Safe and Effective in Children.
  Bader, P; Klingebiel, T; Schaudt, A; Theurer-Mainka, U; Handgretinger, R; Lang, P; Niethammer, D; Beck, J F // Kidney; Nov/Dec99, Vol. 8 Issue 6, p258 

  Evaluates the long-term experience with kidney transplantation in children to determine morbidity and mortality and to identify the factors that affected outcome. One-year graft and patient survival rates; Most common causes of graft failure; Possible pediatric renal transplantation with...

• Peak CsA Levels Linked to Improved Liver Graft Results.
  Bader, P; Klingebiel, T; Schaudt, A; Theurer-Mainka, U; Handgretinger, R; Lang, P; Niethammer, D; Beck, J F // Kidney; Nov/Dec99, Vol. 8 Issue 6, p266 

  Examines whether treatment with Neoral (NEO), a formulation of cyclosporine, would have a lower incidence of acute graft rejection in liver transplant recipients than Sandimmune (SIM). Relationships between pharmacokinetic parameters and clinical outcomes after transplantation; Comparable...

• Kidney recipients with multiple AR episodes have worse outcome.
  Bader, P; Klingebiel, T; Schaudt, A; Theurer-Mainka, U; Handgretinger, R; Lang, P; Niethammer, D; Beck, J F // Kidney; Jan/Feb2001, Vol. 10 Issue 1, p32 

  Presents an abstract of the study 'Clinical Determinants of Multiple Acute Rejection Episodes in Kidney Transplant Recipients,' by A. Humar, W.D. Payne, D.E.R. Sutherland et al.

• Data confirm protective effect of MMF on long-term graft survival.
  Bader, P; Klingebiel, T; Schaudt, A; Theurer-Mainka, U; Handgretinger, R; Lang, P; Niethammer, D; Beck, J F // Kidney; Jan/Feb2001, Vol. 10 Issue 1, p33 

  Presents an abstract of the study 'Mycophenolate Mofetil Reduces Late Renal Allograft Loss Independent of Acute Rejection,' by A.O. Ojo, H.-U. Meier-Kriesche, J.A. Hanson et al.

• Absence of change in serum creatinine does not preclude acute rejection.
  Bader, P; Klingebiel, T; Schaudt, A; Theurer-Mainka, U; Handgretinger, R; Lang, P; Niethammer, D; Beck, J F // Kidney; Jan/Feb2001, Vol. 10 Issue 1, p34 

  Presents an abstract of the study 'Acute Rejection Presenting as Nephrotic Syndrome,' by I. Ahmad, S.R. Abul-Ezz, P.D. Walker et al.

• Donor age and storage solution may adversely affect graft function.
  Bader, P; Klingebiel, T; Schaudt, A; Theurer-Mainka, U; Handgretinger, R; Lang, P; Niethammer, D; Beck, J F // Kidney; Jan/Feb2001, Vol. 10 Issue 1, p37 

  Presents an abstract of the study 'Fate of Kidneys From the Same Donor Grafted Into Different Recipients: Do They Behave Similarly and Are they Influenced by Donor-related Factors?,' by E. Bertoni, M. Zanazzi, A. Rosati et al.

• Sirolimus with CSA/prednisone decreases acute rejection.
  Bader, P; Klingebiel, T; Schaudt, A; Theurer-Mainka, U; Handgretinger, R; Lang, P; Niethammer, D; Beck, J F // Kidney; Jan/Feb2001, Vol. 10 Issue 1, p41 

  Presents an abstract of the study 'Efficacy of Sirolimus Compared With Azathioprine for Reduction of Acute Renal Allograft Rejection: A Randomised Multicentre Study,' by B.D. Kahan.

• Transplant rules and quality.
  Swim, Eric // Modern Healthcare; 6/11/2007, Vol. 37 Issue 24, p21 

  A letter to the editor is presented in response to the article "Transplant Rejections?" which appeared in the May 21, 2007 issue.

• Male rejection.
  Swim, Eric // New Scientist; 11/4/95, Vol. 148 Issue 2002, p12 

  Reports that livers donated by men are more likely to be rejected than livers from female donors. Association between sex of donors and organ rejection in liver transplants.

• Lower Extremity Bypass Graft Revision in Diabetics.
  Toursarkissian, Boulos; D'Ayala, Marcus; Shireman, Paula K.; Schoolfield, John; Sykes, Mellick T. // Vascular Surgery; Sep/Oct2001, Vol. 35 Issue 5, p369 

  Investigates the use of lower extremity bypass graft revision in diabetics in San Antonio, Texas. Evaluation of routine angiography before graft revision in patients; Discussion on the incidence of recurrent stenosis; Comparison between preoperative angiography and duplex scanning before the...

• OKT3 Results in Rejection Reversal Rate of 98%.
  Toursarkissian, Boulos; D'Ayala, Marcus; Shireman, Paula K.; Schoolfield, John; Sykes, Mellick T. // Kidney; May/Jun98, Vol. 7 Issue 3, p128 

  Discusses the abstract of the research paper 'Efficacy of OKT3 as primary therapy for histologically confirmed acute renal allograft rejection,' by S. Kamath, D. Dean et al and published in a 1997 issue of the journal 'Transplantation.'

• The art of tolerance.
  Starzl, Thomas // Nature Medicine; Sep98, Vol. 4 Issue 9, p1006 

  In a mouse skin transplant model in which donor and recipient mice differ by only one minor histocompatibility antigen, graft tolerance can be induced up to ten days after transplantation, but endures only if there is persistence of migratory antigen (pages 1015-1019).

• Reply to Failure of combined costimulatory blockade in animal transplant model.
  Li, Yongsheng; Strom, Terry B. // Nature Medicine; Feb2000, Vol. 6 Issue 2, p115 

  Replies to a comment on the authors' paper 'Failure of combined costimulatory blockade in animal transplant model.' Point about the ability of costimulation blockade using anti-CD154 and CTLA4-Ig to produce permanent engraftment in allograft models.

• A rendezvous before rejection: Where do T cells meet transplant antigens?
  Briscoe, David M.; Sayegh, Mohamed H. // Nature Medicine; Mar2002, Vol. 8 Issue 3, p220 

  Highlights the role of CD8 T cell-endothelial cell interactions in mediating graft rejection and ponders on the meeting place of T cells and transplant antigens. Occurrence of slow organ dysfunction resulting in chronic attrition of grafts; Role of indirect allorecognition in acute rejection;...

• Leucocytosis is not a manifestation of rejection.
  Daar, A.S.; Morris, P.J.; Oliver, D.O. // British Medical Journal; 12/17/1977, Vol. 2 Issue 6102, p1570 

  Analyzes the leucocyte response to allograft rejection in Great Britain. Responsibility of leucocytes and platelets in mediating graft damage; Effect of large doses of steroids; Role of rejection process on the leucocyte count decrease.

• Update in Immunosuppression.
  Huizinga, Robert // Nephrology Nursing Journal; Jun2002, Vol. 29 Issue 3, p261 

  Talks about the status of renal transplantation and the focus of immunosuppression in the prevention of chronic rejection. Discussion on B cells and T cells, two types of cells that fight infection in the immune system; Information on complete and partial immunosuppression; Preparation of...

• Modified Salter's innominate osteotomy.
  Zerrog, B.; Al-Zahrani, S.; Ali, A. Abdulrahman // Journal of the Royal College of Surgeons of Edinburgh; Aug98, Vol. 43 Issue 4, p262 

  Focuses on the treatment of patients with congenital dislocation of the hip with a modified Salter's innominate osteotomy in Saudi Arabia. Use of rejected femoral segment in stabilizing Salter's osteotomy; Indication of bone healing and incorporation of femoral bone graft with acetabulum;...

• Role of Cytokines in Allograft Rejection.
  Gorczynski, Reginald M. // Current Pharmaceutical Design; Jul2001, Vol. 7 Issue 11, p1039 

  This review examines the evidence, both from experimental models and Numerous clinical settings, that has suggested that suppression of acute allograft Rejection correlates with a relative decrease in type-1 cytokine production and an increase in type-2 cytokine production. This correlation has...

• COMPARISON OF ANTERIOR AND POSTERIOR ILIAC CREST BONE GRAFTS IN TERMS OF HARVEST-SITE MORBIDITY AND FUNCTIONAL OUTCOMES.
  Ahlmann, Elke; Patzakis, Michael; Roidis, Nikolaos; Shepherd, Lane; Holtom, Paul // Journal of Bone & Joint Surgery, American Volume; May2002, Vol. 84 Issue 5, p716 

  Background : Previous studies have demonstrated high complication rates after harvest of iliac crest bone grafts. This study was undertaken to compare the morbidity related to the harvest of anterior iliac crest bone graft with that related to the harvest of posterior iliac crest bone graft and...

• Severe Graft Versus Host Disease.
  Solberg, Lawrence A. // Oncologist; Sep2011, Vol. 16 Issue 9, p1346 

  The poem "Severe Graft Versus Host Disease," by Lawrence A. Solberg is presented. First Line: So I am seeing you; Last Line: I can not achieve alone.

• Reply to �Transplant rejection: Mind your T-cell language�.
  Sacks, Steven; Pratt, Julian // Nature Medicine; Oct2002, Vol. 8 Issue 10, p1043 

  Replies to comments on the effects of regulation by the local transplant complement, on T cell interaction with donor antigen. Use of primed T cells; Recognition that T cells of effector/memory phenotype could be the T cells involved; Consideration of the effect of complement on unprimed cells...

• Transplant rejection: Mind your T-cell language.
  Lakkis, Fadi G. // Nature Medicine; Oct2002, Vol. 8 Issue 10, p1043 

  Focuses on how the complement system in transplantation influence the immune process that leads to rejection. Increase of the efficiency of T cell engagement with the donor antigen by the local complement; Disparate homing patterns and activation requirements of naive T cells.

• Role of circulating lipid abnormalities in chronic renal allograft rejection.
  Kasiske, Bertram L. // Kidney International Supplement; Jul1999, Issue 71, pS-28 

  Examines the role of circulating lipid abnormalities in chronic renal allograft rejection. Correlation between plasma lipid levels and acute and chronic rejection; Influence of plasma lipids on the immunosuppressive effects of cyclosporine A; Evidence of increase prevalence of oxidized...

• Effect of HMG-CoA reductase inhibitors on chronic allograft rejection.
  Katznelson, Steven // Kidney International Supplement; Jul1999, Issue 71, pS-117 

  Examines the effect of 3-hydroxy-3-methyl-glutaryl co-enzyme A reductase inhibitors (HRI) on chronic allograft rejection. Decrease in the incidence of chronic rejection; Identification of the inhibitory effect of HRI on lymphoid cell lines; Efficacy of HRI in up-regulating nitric oxide synthesis.

• FDA approves second liver transplant drug.
  Katznelson, Steven // FDA Consumer; Jul/Aug94, Vol. 28 Issue 6, p2 

  Reports that a new drug for preventing organ rejection in liver transplant patients received approval from the Food and Drug Administration (FDA) on April 8, 1994. Information on Prograf (tacrolimus); Immunosuppressant drugs; Adverse effects.

• Corneal transplant rejection following influenza vaccination.
  Wertheim, Michael S.; Keel, M.; Cook, S. D.; Tole, D. M. // British Journal of Ophthalmology; Jul2006, Vol. 90 Issue 7, p925 

  A letter to the editor is presented in response to the article about corneal transplant rejection following influenza vaccination in the previous issue.

• Measurement of serum amyloid A protein concentrations as test of renal allograft rejection in patients with initially non-functioning grafts.
  Maury, C.P.J.; Teppo, A-M; Ahonen, J.; v. Willebrand, E. // British Medical Journal (Clinical Research Edition); 2/4/1984, Vol. 288 Issue 6414, p360 

  Examines the serum amyloid A protein concentrations in transplant patients with an initially non-functioning grafts. Effect of rejections on the measurement of the concentration; Implications on the rise of the concentration; Relevance of serum amyloid A concentrations in identifying acute...

• Cytokine Receptor Expression Differs in Acute Rejection.
  Maury, C.P.J.; Teppo, A-M; Ahonen, J.; v. Willebrand, E. // Kidney; Nov/Dec98, Vol. 7 Issue 6, p266 

  Presents an abstract of the study 'Cytokine Receptor Expression Differs in Acute Rejection,' by H.E. Corey et al published in 1997.

• Low-Dose ATG Protects against Acute Rejection.
  Maury, C.P.J.; Teppo, A-M; Ahonen, J.; v. Willebrand, E. // Kidney; Nov/Dec98, Vol. 7 Issue 6, p267 

  Presents an abstract of the study 'Low-Dose ATG Protects against Acute Rejection,' by D. Thibaudin et al published in 1998.

• MMF Successfully Reverses Refractory Graft Rejection.
  Maury, C.P.J.; Teppo, A-M; Ahonen, J.; v. Willebrand, E. // Kidney; Nov/Dec98, Vol. 7 Issue 6, p276 

  Presents an abstract of the study 'MMF Successfully Reverses Refractory Graft Rejection,' by G. Morris-Stiff and W.A. Jurewicz published in 1998.

• Low-Dose ATG And OKT3 Are Effective for Acute Steroid-Resistant Rejection.
  Maury, C.P.J.; Teppo, A-M; Ahonen, J.; v. Willebrand, E. // Kidney; Nov/Dec98, Vol. 7 Issue 6, p276 

  Presents an abstract of the study 'Low-Dose ATG and OKT3 Are Effective for Acute Steroid-Resistant Rejection,' by C. Mariat et al published in 1998.

• Ways around rejection.
  Vaux, David L. // Nature; 10/19/1995, Vol. 377 Issue 6550, p576 

  Reports on the rejection of grafted testicular tissues in mice. Survival of mismatched grafts of mouse testes; Immune-privileged sites in the testes; Rejection of mismatched grafts from other tissues.

• Th[sub 1] /Th[sub 2] cytokines and ICAM�1 levels post-liver transplant do not predict early rejection.
  Granot, E.; Tarcsafalvi, A.; Emre, S.; Sheiner, P.; Guy, S.; Schwartz, M. E.; Boros, P.; Miller, C. M. // Mediators of Inflammation; Feb2000, Vol. 9 Issue 1, p35 

  TH[sub 1] DERIVED cytokines IFN-? and IL�2, Th[sub 2] cytokine IL�4, and ICAM�1 have been implicated in liver allograft rejection. In order to determine whether monitoring of cytokine profiles during the first days post-liver transplant can predict early rejection we measured IFN-gg,...

• Early Allograft Dysfunction Predicts Graft Failure.
  Granot, E.; Tarcsafalvi, A.; Emre, S.; Sheiner, P.; Guy, S.; Schwartz, M. E.; Boros, P.; Miller, C. M. // Kidney; Mar/Apr98, Vol. 7 Issue 2, p75 

  Discusses the abstract of the article 'Impact of acute rejection and early allograft function on renal allograft survival,' by F.G. Cosio, R.P. Pelletiere et al, published in the 1997 issue of the 'Transplantation' journal.

• Poorest Outcome Occurs with Associated DGF and Rejection.
  Granot, E.; Tarcsafalvi, A.; Emre, S.; Sheiner, P.; Guy, S.; Schwartz, M. E.; Boros, P.; Miller, C. M. // Kidney; Mar/Apr99, Vol. 8 Issue 2, p76 

  Presents an abstract of the study 'Delayed graft function does not reduce the survival of renal transplant allografts,' by R. Marcen, L. Orofino, J. Pascual, et al.

• Up-regulation of inflammation early posttransplant may cause chronic rejection.
  Granot, E.; Tarcsafalvi, A.; Emre, S.; Sheiner, P.; Guy, S.; Schwartz, M. E.; Boros, P.; Miller, C. M. // Kidney; Jan/Feb2001, Vol. 10 Issue 1, p34 

  Presents an abstract of the study 'Early Up-regulation of Macrophages and Myofibroblasts: A New Marker for Development of Chronic Renal Allograft Rejection,' by H.L. Pilmore, D.M. Painter and G.A. Bishop.

• Treatment with cyclosporin and risks of graft rejection in male kidney and heart transplant recipients with non-O blood.
  Hendriks, G.F.J.; Steenberge, E.P.M. v.; Schreuder, G.M. Th.; Wenting, G.J.; Mochtar, B.; Bos, E.; Simoons, M.L.; Balk, A.H.M.M.; Laird-Meeter, K.; Essed, C.E.; Baumgartner, D.; Jeekel, J.; Weimar, W. // BMJ: British Medical Journal (International Edition); 10/8/88, Vol. 297 Issue 6653, p888 

  Examines the treatment with cyclosporin A and risks of graft rejection in male kidney and heart transplant recipients with non-O blood. Need for an exchange strategy of donor hearts; Differences in immune responsiveness; Obtainment of serial endomyocardial biopsy specimens.

• IgA Nephropathy Has No Impact on Graft Rejection.
  Hendriks, G.F.J.; Steenberge, E.P.M. v.; Schreuder, G.M. Th.; Wenting, G.J.; Mochtar, B.; Bos, E.; Simoons, M.L.; Balk, A.H.M.M.; Laird-Meeter, K.; Essed, C.E.; Baumgartner, D.; Jeekel, J.; Weimar, W. // Kidney; May/Jun98, Vol. 7 Issue 3, p123 

  Discusses the abstract of the research paper 'Rejection rates in kidney transplant patients with and without IgA nephropathy,' by P. Freese, G. Norden et al and published in a 1997 issue of 'Nephrology, Dialysis and Transplantation.'

• Patients with Borderline Changes Fall into Two Categories.
  Hendriks, G.F.J.; Steenberge, E.P.M. v.; Schreuder, G.M. Th.; Wenting, G.J.; Mochtar, B.; Bos, E.; Simoons, M.L.; Balk, A.H.M.M.; Laird-Meeter, K.; Essed, C.E.; Baumgartner, D.; Jeekel, J.; Weimar, W. // Kidney; May/Jun98, Vol. 7 Issue 3, p124 

  Discusses the abstract of the research paper 'Clinical significance of renal allograft biopsies with 'borderline changes,' as defined in the Banff schema,' by R. Saad, H.A. Gritsch et al and published in a 1997 issue of 'Transplantation.'

• OKT3 Is Effective for Steroid-Resistant Acute Rejection.
  Hendriks, G.F.J.; Steenberge, E.P.M. v.; Schreuder, G.M. Th.; Wenting, G.J.; Mochtar, B.; Bos, E.; Simoons, M.L.; Balk, A.H.M.M.; Laird-Meeter, K.; Essed, C.E.; Baumgartner, D.; Jeekel, J.; Weimar, W. // Kidney; May/Jun98, Vol. 7 Issue 3, p132 

  Discusses the abstract of the research paper 'OKT3 for the treatment of steroid-resistant acute renal allograft rejection,' by J.T. Jagose, R.R. Bailey et al and published in a 1997 issue of the journal 'Nephrology.'

• Possible effect of time on renal allograft rejection.
  Knapp, M.S.; Cove-Smith, J.R.; Dugdale, R.; Mackenzie, N.; Pownall, R. // British Medical Journal; 1/13/1979, Vol. 1 Issue 6156, p75 

  Examines the effect of time on renal allograft rejection. Cause on the changes in plasma creatinine concentrations; Use of extrapolating sequential measurements of plasma creatinine concentration; Observation on the commonality of rejection.

• The fine cytokine line between graft acceptance and rejection.
  Holzknecht, Zoie E.; Platt, Jeffrey L. // Nature Medicine; May2000, Vol. 6 Issue 5, p497 

  Reports on a study which provides useful and important insights into the pathogenesis of acute vascular graft rejection. Investigation of rat hearts transplanted into various strains of mice; Development of immune responses in the mice due to cytokines; Implications for the mechanisms through...

• Annexin-V imaging for noninvasive detection of cardiac allograft rejection.
  Narula, Jagat; Acio, Elmo R.; Narula, Navneet; Samuels, Louis E.; Fyfe, Billy; Wood, Diana; Fitzpatrick, Jane M.; Raghunath, P.N.; Tomaszewski, John E.; Kelly, Christine; Steinmetz, Neil; Green, Allan; Tait, John F.; Leppo, Jeffrey; Blankenberg, Francis G.; Jain, Diwakar; Strauss, H. William // Nature Medicine; Dec2001, Vol. 7 Issue 12, p1347 

  Heart transplant rejection is characterized pathologically by myocyte necrosis and apoptosis associated with interstitial mononuclear cell infiltration. Any one of these components can be targeted for noninvasive detection of transplant rejection. During apoptotic cell death, phosphatidylserine,...

• Local synthesis of complement component C3 regulates acute renal transplant rejection.
  Pratt, Julian R.; Basheer, Shamim A.; Sacks, Steven H. // Nature Medicine; Jun2002, Vol. 8 Issue 6, p582 

  Accumulating evidence suggests that innate immunity interacts with the adaptive immune system to identify potentially harmful antigens and eliminate them from the host. A central facet of innate immunity is complement, which for some time has been recognized as a contributor to inflammation in...

• Spontaneous acceptance of liver transplants in rodents: Evidence that liver leucocytes induce recipient T-cell death by neglect.
  Bishop, G Alex; Wang, Chuanmin; Sharland, Alexandra F; McCaughan, Geoffrey W // Immunology & Cell Biology; Feb2002, Vol. 80 Issue 1, p93 

  Summary In many animal models transplanted livers are not rejected, even when there is a complete MHC mismatch between the donor and recipient and the recipient is not immunosuppressed. This distinguishes liver transplants from other organs, such as kidneys and hearts, which are rapidly rejected...

• Infections after Cardiac Transplantation: Relation to Rejection Therapy.
  Mason, Jay W.; Stinson, Edward B.; Hunt, Sharon A.; Schroeder, John S.; Rider, Alan K. // Annals of Internal Medicine; Jul76, Vol. 85 Issue 1, p69 

  Focuses on a study which analyzed the relation of the treatment of acute graft rejection episodes in late postoperative cardiac transplant patients to infection. Relation of infection to rejection therapy; Analysis of infection incidence; Methodology of the study; Results and discussion.

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