Citations with the tag: EMBRYONIC stem cells

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  • Scientists react to government indecision.
    Brown, Phyllida // Nature Medicine; Aug99, Vol. 5 Issue 8, p855 

    Discusses the government's delay in deciding whether to permit research into the therapeutic use of human embryonic stem cells in Great Britain. Creation of anti-science climate; Reaction of the researchers towards the delay.

  • Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord.
    McDonald, John W.; Liu, Xiao-Zhong; Qu, Yun; Liu, Su; Mickey, Shannon K.; Turetsky, Dorothy; Gottlieb, David I.; Choi, Dennis W. // Nature Medicine; Dec99, Vol. 5 Issue 12, p1410 

    Transplantation approaches using cellular bridges, fetal central nervous system cells, fibroblasts expressing neurotrophin-3 (ref. 6), hybridoma cells expressing inhibitory protein-blocking antibodies, or olfactory nerves ensheathing glial cells transplanted into the acutely injured spinal cord...

  • Apc modulates embryonic stem-cell differentiation by controlling the dosage of �-catenin signaling.
    Kielman, Menno F.; Rindap��, Maaret; Gaspar, Claudia; van Poppel, Nicole; Breukel, Cor; van Leeuwen, Sandra; Taketo, Makoto Mark; Roberts, Scott; Smits, Ron; Fodde, Riccardo // Nature Genetics; Dec2002, Vol. 32 Issue 4, p594 

    The Wnt signal-transduction pathway induces the nuclear translocation of membrane-bound �-catenin (Catnb) and has a key role in cell-fate determination. Tight somatic regulation of this signal is essential, as uncontrolled nuclear accumulation of �-catenin can cause developmental defects and...

  • Japan okays stem cells.
    Saegusa, Asako // Nature Biotechnology; Mar2000, Vol. 18 Issue 3, p246 

    Reports on the approval given by the bioethics committee of Japan's Science and Technology Council for research involving the use of embryonic stem cells. Reason cited by the committee for granting approval to the research; Plans of the committee to draw up guidelines for embryonic stem cell...

  • High-yield selection and extraction of two promoter-defined phenotypes of neural stem cells from the fetal human brain.
    Keyoung, H. Michael; Roy, Neeta S.; Benraiss, Abdellatif; Louissaint, Abner; Suzuki, Akira; Hashimoto, Mitsuhiro; Rashbaum, William K.; Okano, Hideyuki; Goldman, Steven A. // Nature Biotechnology; Sep2001, Vol. 19 Issue 9, p843 

    Neural stem and precursor cells reside in the ventricular lining of the fetal forebrain, and may provide a cellular substrate for brain repair. To selectively identify and extract these cells, we infected dissociated fetal human brain cells with adenoviruses bearing the gene for green...

  • German researchers set to receive Israeli stem-cell shipment.
    Watzman, Haim // Nature; 1/16/2003, Vol. 421 Issue 6920, p199 

    Reports on the shipment of human embryonic stem cell by Israeli collaborators to German researchers. German and Israeli Groups that have collaborated for the stem cells; Use of the stem cells by the German group; Reasons for importing stem cells from Israel.

  • Cells without heartache.
    Coghlan, Andy // New Scientist; 4/27/2002, Vol. 174 Issue 2340, p9 

    Declares the ethical objections to harvesting cells from embryos in Cambridge, England. Experiments on cloned frog embryos; Demonstration of the experiment made by John Gurdon of the Wellcome Cancer Research Institute; Development of embryos to several tissue types.

  • Cell growth: RAC1 sizes up mTOR.
    Schuldt, Alison // Nature Reviews Molecular Cell Biology; Jun2011, Vol. 12 Issue 6, p343 

    The author discusses the study which observes that conditional deletion of RAC1 from primary mouse embryonic fibroblasts (MEFs), B cells or T cells reduced cell size.

  • JDF NEWS.
    Schuldt, Alison // Countdown; Summer2002, Vol. 23 Issue 3, p48 

    Reports global developments related to medicine as of July 2002. Support of Australian Prime Minister John Howard for embryonic stem cell research; Sponsorship of the 'Roaring '20s Remembered' gala by UnitedHealthcare; Launch of the Arizona Chapter's Promise Gala 2002.

  • Back to the Future.
    Beardsley, Timothy M. // BioScience; Sep2007, Vol. 57 Issue 8, p643 

    The article discusses reports published within the issue including Sa Cai, Xiaobing Fu and Zhiyong Sheng on alternative ways of producing human cells using embryonic stem cells.

  • Corrigendum: Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling.
    Chambers, Stuart M; Fasano, Christopher A; Papapetrou, Eirini P; Tomishima, Mark; Sadelain, Michel; Studer, Lorenz // Nature Biotechnology; May2009, Vol. 27 Issue 5, p485 

    A corrigendum is presented for the article "Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling," which was published in the 2009 volume 27 issue.

  • Monoclonal mice generated by nuclear transfer from mature B and T donor cells.
    Hochedlinger, Konrad; Jaenisch, Rudolf // Nature; 2/28/2002, Vol. 415 Issue 6875, p1035 

    Focuses on the use of embryonic stem cells for cloning. Inefficiency of somatic cell cloning; Generation of monoclonal mice by nuclear transfer from mature lymphocytes; Procedure of the embryonic stem cell cloning.

  • Embryonic stem cells grown from primates.
    Hochedlinger, Konrad; Jaenisch, Rudolf // Science Teacher; Nov95, Vol. 62 Issue 8, p12 

    Reports that scientists at the University of Wisconsin-Madison have harvested and grown embryonic stem cells from primates for the first time in a laboratory. Future tests on its isolation and propagation for transplants on diseased human tissue; Development of cell types in the body.

  • Back to the Future.
    Beardsley, Timothy M. // BioScience; Sep2007, Vol. 57 Issue 8, p643 

    The article discusses reports published within the issue including Sa Cai, Xiaobing Fu and Zhiyong Sheng on alternative ways of producing human cells using embryonic stem cells.

  • Gene expression: Uncovering proteome complexity.
    Flintoft, Louisa // Nature Reviews Genetics; Dec2011, Vol. 12 Issue 12, p807 

    The article discusses a study on new approaches for proteome complexity and translational dynamics which references the study "Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes," by N.T. Ingolia in the November 2011 issue of "Cell."

  • Role of ERas in promoting tumour-like properties in mouse embryonic stem cells.
    Takahashi, Kazutoshi; Mitsui, Kaoru; Yamanaka, Shinya // Nature; 5/29/2003, Vol. 423 Issue 6939, p541 

    Embryonic stem (ES) cells are pluripotent cells derived from early mammalian embryos. Their immortality and rapid growth make them attractive sources for stem cell therapies; however, they produce tumours (teratomas) when transplanted, which could preclude their therapeutic usage. Why ES cells,...

  • Europe dithers over regulations for stem-cell research.
    Abbott, Alison // Nature; 12/11/2003, Vol. 426 Issue 6967, p595 

    Reports on Europe's debate on research using embryonic stem cells. Failure of research ministers of the European Union's (EU) member states to agree on whether EU funding should be available for research using human embryonic stem cells; Expiration of the moratorium on research funding;...

  • Team's stem cell work suggests a diabetes breakthrough.
    Abbott, Alison // Asian Pacific Post; 12/27/2008, p33 

    The article reports on the development of an unlimited number of pure insulin-producing cells from embryonic stem cells by Lim Sai Kiang and Li Guodong of the Institute of Medical Biology in Singapore.

  • Correction.
    Abbott, Alison // Nature; 6/21/2007, Vol. 447 Issue 7147, p897 

    A correction to the article "Simple switch turns cells embryonic" is presented.

  • Human stem cells become more established.
    Frederickson, Robert // Nature Biotechnology; Apr2000, Vol. 18 Issue 4, p370 

    Confirms the generation of embryonic stem cells from human blastocysts.

  • Human embryonic stem cell lines derived from single blastomeres.
    Irina Klimanskaya; Chung, Young; Sandy Becker; Shi-Jiang Lu; Lanza, Robert // Nature; 3/15/2007, Vol. 446 Issue 7133, p342 

    A correction to the article "Human Embryonic Stem Cell Lines Derived From single Blastomeres," by Irina Klimanskaya, Young Chung, Sandy Becker, Shi-Jiang Lu and Robert Lanza that was published in the earlier issue of the journal "Nature" is presented.

  • Editorial.
    Knuuttila, Tarja; Hyssalo, Sampsa // Science Studies; Jun2007, Vol. 20 Issue 1, p3 

    The article discusses various reports published within the issue, including "From Core Set to Assemblage: On the Dynamics of Exclusion and Inclusion in the Failure to Derive Beta Cells from Embryonic Stem Cells," by Mike Michael and colleagues, and "Effects of 'Mode 2'-Related Policy on the...

  • Non-injection methods for the production of embryonic stem cell-embryo chimaeras.
    Wood, Stephen A.; Allen, Nick D. // Nature; 9/2/1993, Vol. 365 Issue 6441, p87 

    Contrasts the morulae aggregation and blastocyst injection techniques for the production of germline chimaeras. Same percentage of germline chimaeras for both methods; Pluripotency of the embryonic stem cells as the most critical parameter; Savings in time and equipment when using aggregation...

  • ES cell media.
    Battaglia, Massimo // Nature Biotechnology; Feb2002, Vol. 20 Issue 2, p119 

    Discusses the media for embryonic stem cells. Testing of human embryonic fibroblasts; Maintenance of human embryonic stem cells on matrices and media conditioned by irradiated primary mouse feeders; Evaluation of immortalized human cell lines.

  • pluripotent, pluripotential.
    Battaglia, Massimo // Taber's Cyclopedic Medical Dictionary (2009); 2009, Issue 21, p1809 

    The definitions of the medical terms "pluripotent" or "pluripotential," which pertains to an embryonic cell that can form various types of cells, or having a number of different functions, are presented.

  • blastoderm.
    Battaglia, Massimo // Taber's Cyclopedic Medical Dictionary (2009); 2009, Issue 21, p276 

    An encyclopedia entry for blastoderm, a disk of cells, is presented.

  • Embryonic stem cell cookery.
    Rossant, Janet // Nature Cell Biology; Jul2002, Vol. 4 Issue 7, pE175 

    Reviews the book 'Embryonic Stem Cells: Methods and Protocols,' edited by Kursad Turksen.

  • Ask Professor Ossolotch.
    Rossant, Janet // Current Science; 12/12/2008, Vol. 94 Issue 8, p15 

    The article provides an answer to a question on stem cells.

  • Should US fund embryonic-cell research?
    Belsie, Laurent // Christian Science Monitor; 3/13/2001, Vol. 93 Issue 74, p2 

    Discusses controversy over the funding of embryonic stem cell research in the United States, as opponents claim it will violate the dignity of life and advocates hope it will cure diseases.

  • Leukemia Research Fund Abstracts.
    Greaves, Mel; Wolpert, L.; Dzierzak, E.; Sanchez, M.-J.; Miles, C.; Holmes, A.; Tidcombe, H.; Medvinsky, A.; Visser, Jan W.M.; Keij, Ian F.; Zijlmans, J. Mark J.M.; Fibbe, Wlm E.; Ershler, Maxim; Belyavsky, Alexander V.; Enver, T.; Bennett, C.; Brown, J.; Crotta, S.; Dexter, T. // Leukemia (08876924); Jun97, Vol. 11 Issue 6, p897 

    Presents abstracts on leukemia from the 1996 Leukemia Research Fund Symposium. Examination of embryonic cells for the treatment of leukemia; Molecular mechanisms of lineage-specific locus activation in haematopoietic stem cells; Transcriptional regulation of differentiation and leukemogenesis...

  • Forced expression of Genesis, a winged helix transcriptional repressor isolated from embryonic stem cells, blocks granulocytic differentiation of 32D myeloid cells.
    Xu, D; Yoder, M; Sutton, J; Hromas, R // Leukemia (08876924); Feb98, Vol. 12 Issue 2, p207 

    We recently isolated and characterized a novel member of the winged helix (formerly HNF-3/Forkhead) transcriptional regulatory family, termed Genesis. Genesis was found to be a transcriptional repressor expressed almost exclusively in embryonic stem cells or embryonal carcinoma cells. This...

  • More reporting needed.
    Sheedy, Michael // Modern Healthcare; 12/13/2004, Vol. 34 Issue 50, p18 

    Presents a letter to the editor in response to the article "Special Report: Election 2004," in the November 29, 2004 issue of the periodical "Modern Healthcare."

  • Unethical decision.
    Moore, Robert E. // Modern Healthcare; 4/13/2009, Vol. 39 Issue 15, p26 

    A letter to the editor is presented in response to the article "Crossing the line," in the March 16, 2009.

  • STEM CELLS, THE NEXT ROUND.
    Heath, Erin // National Journal; 3/10/2001, Vol. 33 Issue 10, p720 

    Highlights the controversy on the use of embryonic stem cells in research. Guidelines on embryonic stem cell research from the United States National Institute of Health; Views by U.S. President George W. Bush on embryonic stem cell research.

  • Scientists grow stem cells in lab.
    Moore, Amy Slugg // RN; Feb99, Vol. 62 Issue 2, p90 

    Reports that scientists have isolated and cultivated stem cells. Production of the stem cells using embryonic tissues.

  • Heparin cofactor II inhibitors arterial thrombosis after endothelial injury.
    He, Li; Vicente, Cristina P.; Westrick, Randal J.; Eitzman, Daniel T.; Tollefsen, Douglas M. // Journal of Clinical Investigation; 1/15/2002, Vol. 109 Issue 2, p213 

    Presents a study that described a mouse model of heparin cofactor II (HCII) deficiency by targeted gene disruption in embryonic stem cells. Methods; Results; Discussion.

  • HESC-DERIVED HEMATOPOIETIC CELLS PREVENT IMMUNE REJECTION.
    He, Li; Vicente, Cristina P.; Westrick, Randal J.; Eitzman, Daniel T.; Tollefsen, Douglas M. // Biotech Business; Mar2003, Vol. 16 Issue 3, p2 

    Provides information on data announced by Geron Corp. that advance the promise of cell therapies based upon human embryonic stem cells in 2003.

  • Court paints with broad brush, upends U.S. stem cell policy.
    Lefkowitz, Jay // Hill; 9/16/2010, Vol. 17 Issue 100, p31 

    In this article the author focuses on the court ruling which emphasized the preclusion of an embryonic stem cell research project from receiving federal fundings by the Dickey-Wicker Amendment if one step of the project results in the destruction of an embryo in the U.S.

  • SCI CHAT.
    Lefkowitz, Jay // Odyssey; Apr2005, Vol. 14 Issue 4, p47 

    Reports that embryonic stem cells do not represent a human life.

  • "Guided Differentiation of Human Embryonic Stem Cells.".
    Lefkowitz, Jay // Fertility Weekly; 2/2/2009, p11 

    An abstract of the conference paper presented during the 2nd Congress of the Asia Pacific Initiative on Reproduction & 6th Biennial Meeting of the Pacific Rim Society for Fertility & Sterility in Singapore on April 11-13, 2008 which discusses the guided differentiation of human embryonic stem...

  • Stem cells: Scorecards for pluripotent cell lines.
    Muers, Mary // Nature Reviews Genetics; Mar2011, Vol. 12 Issue 3, p153 

    The article discusses a study on the differences among human induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) and between each cell lines which references the study "Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent...

  • Genetic modification of murine embryonic stem cells by the gene silencing resistance retroviral vector GCDsap.
    Muers, Mary // Molecular Therapy; May2004 Supplement 1, Vol. 9, p125 

    An abstract to the article "Genetic Modification of Murine Embryonic Stem Cells by the Gene Silencing Resistance Retroviral Vector GCDsap," by Sanae Hamanaka, Joichi Usui, Satoru Takahashi, Hisahiro Yoshida, Michio Nagata, Makoto Otsu, Hiromitsu Nakauchi and Masafumi Onodera is presented.

  • Increased expression of OCT4, SOX2 and FGF4 genes following injection of embryonic stem cell into damaged murine brain.
    Muers, Mary // Molecular Therapy; May2004 Supplement 1, Vol. 9, p198 

    An abstract of the article "Increased Expression of OCT4, SOX2 and FGF4 Genes Following Injection of Embryonic Stem Cell into Damaged Murine Brain," by Anand S. Srivastava, Steve Shenouda, Mohamed E. Moustafa and Ewa Carrier is presented.

  • 20. Targeted Gene Delivery to Embryonic Stem Cells.
    Henckaerts, Els; Zeltner, Nadja; Kattman, Steven; Dutheil, Nathalie; Ward, Peter; Kennedy, Marion; Clement, Nathalie; Rebollo, Patricia; Keller, Gordon; Linden, R. Michael // Molecular Therapy; Jun2005, Vol. 11, p8 

    An abstract of the article "Targeted Gene Delivery to Embryonic Stem Cells," by Els Henckaerts, Nadja Zeltner, Steven Kattman, Nathalie Dutheil, Peter Ward, Marion Kennedy, Nathalie Clement, Patricia Rebollo, Gordon Keller and R. Michael Linden is presented.

  • 89. Amelioration of Gamma Retroviral Silencing during Embryonic Stem Cell-Derived Hematopoiesis: Preclinical Assessment of Safety-Improved Vectors.
    Ramezani, Ali; Hawley, Teresa S.; Hawley, Robert G. // Molecular Therapy; Jun2005, Vol. 11, p36 

    An abstract of the article "Amelioration of Gamma Retroviral Silencing during Embryonic Stem Cell-Derived Hematopoiesis: Preclinical Assessment of Safety-Improved Vectors," by Ali Ramezani, Teresa S. Hawley and Robert G. Hawley is presented.

  • Human embryonic stem cells: The future is now.
    Keller, Gordon; Snodgrass, H. Ralph // Nature Medicine; Feb99, Vol. 5 Issue 2, p151 

    The development of human embryonic stem cells as a research tool and therapeutic option offers a number of potential applications including the replacement of damaged tissues.

  • Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation.
    Aubert, Jer�me; Dunstan, Hannah; Chambers, Ian; Smith, Austin // Nature Biotechnology; Dec2002, Vol. 20 Issue 12, p1240 

    The multilineage differentiation capacity of mouse embryonic stem (ES) cells offers a potential testing platform for gene products that mediate mammalian lineage determination and cellular specialization. Identification of such differentiation regulators is crucial to harnessing ES cells for...

  • Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype.
    Kunath, Tilo; Gish, Gerald; Lickert, Heiko; Jones, Nina; Pawson, Tony; Rossant, Janet // Nature Biotechnology; May2003, Vol. 21 Issue 5, p559 

    Gene targeting via homologous recombination in murine embryonic stem (ES) cells has been the method of choice for deciphering mammalian gene function in vivo. Despite improvements in this technology, it still remains a laborious method. Recent advances in RNA interference (RNAi) technology have...

  • IVF and the history of stem cells.
    Edwards, R.G. // Nature; 9/27/2001, Vol. 413 Issue 6854, p349 

    Examines the historical potential of embryo stem cells. Fundamental approach to alleviating severe incurable human maladies; Origin of the embryo stem cell; Significance of the birth of children conceived in vitro; Characteristics of embryo stem cells.

  • A world of difference.
    Aldhous, Peter // Nature; 12/20/2001-12/27/2001, Vol. 414 Issue 6866, p838 

    Focuses on human embryonic stem (ES) cells research. Support of Great Britain on ES-cell research; Significance of therapeutic cloning; Plans of Advanced Cell Technology (ACT).

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