Citations with the tag: DRUG resistance
Results 1 - 50
- Intensive care unit infections on the rise.
// AHA News; 2/24/97, Vol. 33 Issue 7, p5
Highlights impact of the rapid increase in antibiotic-resistant bacteria on the treatment of intensive care unit patients in the United States. Prolonged hospitalizations; More toxic and expensive antibiotics.
- The rise of antibiotic-resistant infections.
Lewis, Ricki // FDA Consumer; Sep95, Vol. 29 Issue 7, p11
Describes an increased prevalence of antibiotic resistance in microbes. Appearance of disease-causing microbes that resisted penicillin in the 1940s, 1960s and 1980s; Resistance as an outcome of evolution; How antibiotics contribute to resistance; Microbes' interference with the drugs'...
- Clinical digest. Effective antibiotics are in sight after scientists unlock secrets of superbug.
Lewis, Ricki // Nursing Standard; 9/28/2011, Vol. 26 Issue 4, p17
The article reports on research which is being conducted in 2011 on antibiotics which could be effective on antibiotic resistant diseases including the NDM-1, which is also known as the New Delhi modified superbug.
- On the role of schistosome mating structure in the maintenance of drug resistant strains.
Xu, Dashun; Curtis, Jason; Feng, Zhilan; Minchella, Dennis J. // Bulletin of Mathematical Biology; Nov2005, Vol. 67 Issue 6, p1207
Abstract: The effects of drug treatment of human hosts upon a population of schistosome parasites depend upon a variety of factors. Previous models have shown that multiple strains of drug-resistant parasites are likely to be favored as the treatment rate increases. However, such models have...
- Aspirin and Clopidogrel Resistance.
Fosburgh, Daniel // Mayo Clinic Proceedings; Jul2006, Vol. 81 Issue 7, p989
A letter to the editor is presented in response to the article on aspirin and clopidogrel resistance, that was published in the April 2006 issue of the journal "Mayo Clinic Proceedings."
- In reply.
Michos, Erin D.; Ardehali, Reza; Blumenthal, Roger S.; Lange, Richard A.; Ardehali, Hossein // Mayo Clinic Proceedings; Jul2006, Vol. 81 Issue 7, p990
A response by Erin D. Michis, Reza Ardehali, roger S. Blumenthal and Richard A. Lange to a letter to the editor about their article on aspirin and clopidogrel resistance, published in the April 2006 issue is presented.
- Use of new technologies to detect and understand HIV drug resistance.
Kozal, Michael J. // Retrovirology; 2010 Supplement 1, Vol. 7, p1
An abstract of the article "Use of New Technologies to Detect and Understand HIV Drug Resistance," by Michael J. Kozal is presented.
- Faculty Roundtable Discussion.
Frost, Kevin Robert // AIDS Patient Care & STDs; Jul98, Vol. 12 Issue 7, p543
Presents a discussion pertaining to the resistance of drug treatment towards diseases. Identification of the participants in the discussion; Information on resistance testing; In-depth look at the discussion.
- RESISTANT GONORRHEA FOUND.
Frost, Kevin Robert // AIDS Patient Care & STDs; Aug98, Vol. 12 Issue 8, p647
Reports that the United States Centers for Disease Control and Prevention found two cases of gonococcal infection in San Diego, California, which are resistant to fluoroquinolones. What was used to treat the two patients, ages 24 and 22; Strain which caused the disease; Names of drugs which are...
- Introduction of TaqMan HIV-1 Assay Increased Unnecessary Drug Resistance Testing.
Gatanaga, Hiroyuki; Oowa, Minoru; Oka, Shinichi // AIDS Patient Care & STDs; Apr2010, Vol. 24 Issue 4, p203
A letter to the editor is presented related to the testing of drug resistance.
- A New Kind of Resistance Training.
Foster, R. Daniel // Men's Fitness; Oct2002, Vol. 18 Issue 10, p69
Offers information on HIV drug-resistance testing.
- Antibiotic Resistance in Livestock: More at Stake than Steak.
Schmidt, Charles W. // Environmental Health Perspectives; Jul2002, Vol. 110 Issue 7, pA396
Focuses on the causes of antibiotic resistance in livestock. Pressure on agriculture to alter its use of antibiotics; Food chains' decision not to buy chickens treated with the antibiotic enrofloxacin; Proposed bills in the U.S. on the phaseout of the use of antibiotic formulations used in both...
- Emerging Importance of Multidrug-Resistant Acinetobacter Species and Stenotrophomonas maltophilia as Pathogens in Seriously Ill Patients: Geographic Patterns, Epidemiological Features, and Trends in the SENTRY Antimicrobial Surveillance Program...
Gales, A. C.; Jones, R. N.; Forward, K. R.; Linares, J.; Sader, H. S.; Verhoef, J. // Clinical Infectious Diseases; 5/16/2001 Supplement 2, Vol. 32, pS104
As part of the SENTRY Antimicrobial Surveillance Program, a total of 1078 Acinetobacter species and 842 Stenotrophomonas maltophilia isolates were collected between January 1997 and December 1999 from 5 geographic regions (Canada, the United States, Latin America, Europe, and the Asia-Pacific)....
- Better Control of Antibiotic Resistance.
Guillemot, D.; Courvalin, P. // Clinical Infectious Diseases; 8/15/2001, Vol. 33 Issue 4, p542
This text summarizes the conclusions of the French Working Party to Promote Research to Control Bacterial Resistance, initiated by the French Institute for Public Health Surveillance. The goal was to identify and prioritize the research areas most pertinent to the evolution of antibiotic...
- Antimicrobial-Resistant, Gram-Positive Bacteria among Patients Undergoing Chronic Hemodialysis.
D'Agata, Erika M.C. // Clinical Infectious Diseases; 11/15/2002, Vol. 35 Issue 10, p1212
Numerous antimicrobial-resistant pathogens (ARPs) have emerged among patients who undergo chronic hemodialysis (CHD), including vancomycin-resistant enterococci, vancomycin-resistant coagulase-negative staphylococci, Staphylococcus aureus with reduced susceptibility to vancomycin, and...
- Resistance monitoring in Denmark, 1997 - DANMAP.
D'Agata, Erika M.C. // Weekly Epidemiological Record; 4/23/99, Vol. 74 Issue 16, p125
Reports the release of the second report of the Danish Antimicrobial Resistance Monitoring and Research Program in Denmark. Decline of antibiotics consumption in human treatment; List of antibiotic resistance bacteria; Implementation of a ban on the use of avoparcin.
- Where hospitals are stanching antibiotic resistance.
Hollon, Thomas // Drug Topics; 8/5/2002, Vol. 146 Issue 15, p55
Focuses on antibiotic-resistant infections in hospitals in the U.S. Prevalence of infections; Problems associated with antibiotic resistance; Causes and a possible solution.
- Officials try incentives, PR against spreading drug resistance.
Zwillich, Todd // Drug Topics; 8/04/2003, Vol. 147 Issue 15, p36
Reports on the U.S. government's efforts to combat antibiotic resistance. Factors contributing to the rise of antimicrobial resistance; Therapeutic agents tested for a range of resistant organisms; Focus of the government's educational campaign.
- A novel energy dependent mechanism reducing daunorubicin accumulation in acute myeloid leukemia.
Hedley, D W; Xie, S Xiu-Yan; Minden, M D; Choi, C H; Chen, H; Ling, V // Leukemia (08876924); Jan97, Vol. 11 Issue 1, p48
Using cyclosporin A (CsA) to inhibit P-glycoprotein (P-gp) function we showed previously that there was a discordance between the ability of acute myeloid leukemic (AML) blast cells to accumulate daunorubicin and P-gp antigen expression (Xie et al, Leukemia 1995; 9: 1882-1887). This discordance...
- Effect of the multidrug inhibitor GG918 on drug sensitivity of human leukemic cells.
Zhou, D-C; Simonin, G; Faussat, A-M; Zittoun, R; Marie, J-P // Leukemia (08876924); Sep97, Vol. 11 Issue 9, p1516
The drug GG918 has been specifically developed for overcoming MDR phenotype and is now in use in clinical trials. In this study, the effects of GG918 on leukemic cell were investigated using a 3 day MTT assay. Results showed that, in a highly resistant P-gp(+) leukemic cell line, 0.1 �M of...
- Adjuvant treatment with cyclosporin A increases the toxicity of chemotherapy for remission induction in acute non-lymphocytic leukemia.
Damiani, D; Michieli, M; Ermacora, A; Russo, D; Fanin, R; Zaja, F; Baraldo, M; Pea, F; Furlanut, M; Baccarani, M // Leukemia (08876924); Aug98, Vol. 12 Issue 8, p1236
P-glycoprotein (Pgp)-related multidrug resistance (MDR) is frequently observed in acute non-lymphocytic leukemia (ANLL) and is associated with a poor response to standard chemotherapy. Cyclosporin A (CsA) is an effective downmodulator of Pgp-related MDR in vitro and has already been tested for...
- Idarubicin DNA intercalation is reduced by MRP1 and not Pgp.
Smeets, M E P; Raymakers, R A P; Vierwinden, G; Pennings, A H M; Boezeman, J; Minderman, H; de Witte, T M // Leukemia (08876924); Sep99, Vol. 13 Issue 9, p1390
Currently available data regarding the substrate specificity of the multi-drug resistance (MDR) mechanisms P-glycoprotein (Pgp) and MDR-associated protein (MRP1) for idarubicin are inconclusive. A multiparameter flow cytometry method was developed which allows simultaneous quantitative...
- Drug-resistance enables selective killing of resistant leukemia cells: exploiting of drug resistance instead of reversal.
Blagosklonny, M V // Leukemia (08876924); Dec99, Vol. 13 Issue 12, p2031
Drug resistance is a well recognized problem in cancer therapy. Despite the current dogma that drug resistance is always an obstacle for treatment, here I show that it provides opportunities for selective protection of non-resistant cells with killing of drug-resistant cancer cells. According to...
- Clinical significance of CD95, Bcl-2 and Bax expression and CD95 function in adult de novo acute myeloid leukemia in context of P-glycoprotein function, maturation stage, and cytogenetics.
Wuchter, C; Karawajew, L; Ruppert, V; B�chner, T; Schoch, C; Haferlach, T; Ratei, R; D�rken, B; Ludwig, W-D // Leukemia (08876924); Dec99, Vol. 13 Issue 12, p1943
Resistance to chemotherapy-induced apoptosis and a multi-drug-resistance (MDR) phenotype, mainly mediated by P-gly-coprotein (P-gp), contribute to chemotherapy failure in hemato-logic malignancies. To study apoptosis-regulating factors in acute myeloid leukemia (AML), we investigated cell...
- Tracking Drug-Resistant Streptococcus pneumoniae in Oregon: An Alternative Surveillance Method.
Chin, Arthur E.; Hedberg, Katrina // Emerging Infectious Diseases; Sep/Oct99, Vol. 5 Issue 5, p688
With the emergence of drug-resistant Streptococcus pneumoniae, community- specific antimicrobial susceptibility patterns have become valuable determinants of empiric therapy for S. pneumoniae infections. Traditionally, these patterns are tracked by active surveillance for invasive disease,...
- Presence of Class I Integrons in Multidrug-Resistant, Low-Prevalence Salmonella Serotypes, Italy.
Nastasi, Antonino; Mammina, Caterina // Emerging Infectious Diseases; May/Jun2001, Vol. 7 Issue 3, p455
In 1997 to 1999, we detected class I integrons in multidrug-resistant isolates of Salmonella enterica serovars Anatum, Blockley, Brandenburg, Bredeney, Derby, Heidelberg, Livingstone, Newport, Ohio, Panama, Paratyphi B, Saintpaul, Sandiego, and Stanley.
- Bitter resistance.
Sterling, Bruce // Fantasy & Science Fiction; Feb95, Vol. 88 Issue 2, p87
Discusses various aspects of bacterial resistance to antibiotics. Attitudes on superiority over bacteria; Historical background of antibiotics; Lessons learned; Expectations.
- Children and Antibiotics: Cutting Back on Inappropriate Prescriptions.
Sterling, Bruce // HealthFacts; Mar99, Vol. 24 Issue 3, p1
Reports that the widespread inappropriate prescription of antibiotics has caused a worldwide health crisis. Emergence of drug-resistant bacteria; Inappropriateness of antibiotics for viral infections; Concern for overuse of antibiotics in children.
- Possible implications of biocide accumulation in the environment on the prevalence of bacterial antibiotic resistance.
McBain, A.J.; Rickard, A.H.; Gilbert, P. // Journal of Industrial Microbiology & Biotechnology; Dec2002, Vol. 29 Issue 6, p326
The lethality of biocides depends upon their interaction with a number of distinct biochemical targets. This often reflects reactive chemistry for any given agent, such as thiol oxidation. Susceptibility may vary markedly between different target organisms, and changes within the more sensitive...
- Try this 4-drug regimen against drug-resistant TB.
McBain, A.J.; Rickard, A.H.; Gilbert, P. // Modern Medicine; Jul94, Vol. 62 Issue 7, p56
Presents an abstract of the study by A.B. Bloch et al titled `Nationwide survey of drug-resistant tuberculosis in the United States,' published in the March 2, 1994 issue of `Journal of the American Medical Association.'
- Too much of a good thing?
Darlington, Vicki // New Orleans CityBusiness (1994 to 2008); 02/01/99, Vol. 19 Issue 31, p25
Focuses on the growing cases of drug-resistant microorganisms due to the overuse of antibiotics. Instances cited by physicians that pressure health personnel to give antibiotics; Recommendations of health care consultants for doctors to use antibiotics only when necessary.
- Why antibiotics don't always work.
Meyer, Michele // Parenting; Apr99, Vol. 13 Issue 3, p39
Focuses on the increase in antibiotic resistance in children. Overprescription and misuse of antibiotics as a probable cause; Need for elimination of unnecessary prescriptions for antibiotics; Development of drugs designed to fight resistant bacteria; Tips for avoiding antibiotic-resistant...
- SUPERBUGS Unmasking the threat.
Wooten, James M.; Salkind, Alan R. // RN; Mar2003, Vol. 66 Issue 3, p37
Focuses on how bacteria develop resistance. Strains resistant to antibiotics; Options for antibiotic resistant bacteria.
- Bacterial resistance to antibiotics: A ticking bomb.
Cerrato, Paul L. // RN; Nov95, Vol. 58 Issue 11, p71
Presents a summary of a study on bacterial resistance to antibiotic, published in a 1995 issue of `Infection Control and Hospital Epidemiology' journal.
- Vancomycin resistance is not inducible in Leuconostoc, Lactobacillus, Pediococcus and...
Huygens, Flavia // South African Journal of Science; Feb95, Vol. 91 Issue 2, p94
Examines various aspects of the mechanism of vancomycin resistance in eighteen isolates of vancomycin-resistant strains of Leuconostoc, Lactobacillus and Pediococcus. Vancomycin-resistant members of the lactic acid bacteria; Patterns of susceptibility of vancomycin-resistant Gram-positive...
- Gonococcal Infections, CDC's Updated Treatment.
Elliott, William T. // Critical Care Alert; Jun2007 Pharmacology Watch, p1
The article reports on the updated treatment recommendations issued by the U.S. Centers for Disease Control and Prevention (CDC) for gonococcal infections and associated conditions due to the high level of resistance of gonorrhea to fluoroquinolones.
- Virus Resistant to Tamiflu Causing Concern.
Elliott, William T. // Critical Care Alert; March2008 Pharmacology Watch, p2
The article reports that a percentage of the influenza A virus has become resistant to the drug oseltamivir, also known as Tamiflu.
- Plain Old Gonorrhea Increasingly Difficult to Treat.
Kemper, Carol // Internal Medicine Alert; 5/29/2007, Vol. 29 Issue 10, p76
The article focuses on the continuing spread of quinolone-resistant neisseria gonorrhea (QRNG) across the U.S.
- Current issues and trends in antimicrobial resistance.
Kemper, Carol // American Journal of Health-System Pharmacy; 4/15/2002, Vol. 59 Issue 8, p1
Presents self-assessment questions for pharmaceutical professionals about trends in antimicrobial resistance. Impact of antimicrobial resistance on society; Strategies for minimizing antimicrobial resistance.
- Inept vancomycin dosing boosting drug resistance.
Pfeiffer, Naomi // Drug Topics; 10/7/96, Vol. 140 Issue 19, p40
Reports on the factors that cause drug resistance to vancomycin. Faulty drug monitoring; Patients at great risk for resistance; US Centers for Disease Control and Prevention's launch of a study on vancomycin use in a large children's hospital; Treatment for patients with multiresistant strains.
- Resistance starting to build on antiulcer drugs.
McCann, Jean // Drug Topics; 10/7/96, Vol. 140 Issue 19, p45
Reports on an increased incidence of resistance to the antiulcer medications clarithromycin and metronidazole. Alternative treatment; Resistance rates between men and women.
- Germ warfare.
McCann, Jean // Drug Topics; 10/20/97, Vol. 141 Issue 20, p56
Focuses on the 1997 meeting of the Interscience Conference on Antimicrobial Agents & Chemotherapy, at which investigators reported some alarming antibiotic resistance rates. Results of a survey of antimicrobial resistance at medical centers in the Americas and Europe; Penicillin resistance to...
- Infectious disease challenge: Vancomycin-resistant enterococcus and staphylococcus.
Ross, Thomas W. // Drug Topics; 1/5/98, Vol. 142 Issue 1, p76
Presents information on the emergence of vancomycin-resistant enterococcus (VRE). Information on the history and epidemiology of enterococcus; What are the mechanisms of transmission of enterococci; Recommendations for the control of VRE; Details on the treatment of VRE; Detailed information on...
- The Global Impact of Drug Resistance.
Howard, David H.; Scott II, R. Douglas; Packard, Randall; Jones, DeAnn // Clinical Infectious Diseases; 1/15/2003 Supplement 1, Vol. 36, pS4
Measuring the impact of drug resistance is an important step in understanding the scope of the problem and formulating policies to limit the emergence and spread of resistant organisms. Studies have focused on measuring the increased costs, morbidity, and mortality in patients with infections...
- Bacterial Resistance: Origins, Epidemiology, and Impact.
Livermore, David M. // Clinical Infectious Diseases; 1/15/2003 Supplement 1, Vol. 36, pS11
The basic mechanisms of antibacterial resistance are well known, but critical new aspects continue to be discovered. Recently discovered factors with major implications for the emergence, dissemination, and maintenance of resistance include multidrug efflux, hypermutability, integrons, and...
- Tuberculosis Drug Resistance: A Global Threat.
Nachega, Jean B.; Chaisson, Richard E. // Clinical Infectious Diseases; 1/15/2003 Supplement 1, Vol. 36, pS24
Resistance to antituberculosis drugs has been a problem since the era of chemotherapy began. After dramatic outbreaks of multidrug-resistant tuberculosis (MDR-TB) in the early 1990s, resistance became recognized as a global problem. MDR-TB now threatens the inhabitants of countries in Europe,...
- Supremos come and go but staff on the ground are the way to beat bugs.
Appleby, Jo Ann // Nursing Standard; 4/1/2009, Vol. 23 Issue 30, p32
A letter to the editor is presented in response to an article in the March 18, 2009 issue that was concerned with the prevention of drug resistant diseases.
- Multiple Drug-Resistant Chlamydia trachomatis Associated with Clinical Treatment Failure.
Somani, Jyoti; Bhullar, Vinod B.; Workowski, Kimberly A.; Farshy, Carol E.; Black, Carolyn M. // Journal of Infectious Diseases; 4/1/2000, Vol. 181 Issue 4
Examines the correlation between multiple drug-resistant of chlamydia trachomatis and clinical treatment failure in the United States. Use of ligase chain reaction in screening for C. trachomatis; Determination of the isolates and antibiotic susceptibilities of C. trachomatis.
- Variable Prediction of Antiretroviral Treatment Outcome by Different Systems for Interpreting Genotypic Human Immunodeficiency Virus Type 1 Drug Resistance.
De Luca, Andrea; Cingolani, Antonella; Di Giambenedetto, Simona; Trotta, Maria Paola; Baldini, Francesco; Rizzo, Maria Gabriella; Bertoli, Ada; Liuzzi, Giuseppina; Narciso, Pasquale; Murri, Rita; Ammassari, Adriana; Perno, Carlo Federico; Antinori, Andrea // Journal of Infectious Diseases; 6/15/2003, Vol. 187 Issue 12, p1934
To determine the variability of genotypic human immunodeficiency virus (HIV) type 1 drug-resistance interpretation by available expert systems and its clinical implications, 261 subjects for whom a potent antiretroviral regimen was failing who were starting salvage therapy were evaluated. The...
- Persistence of a Highly Resistant Strain of Tuberculosis in New York City during 1990--99.
Munsiff, Sonal S.; Nivin, Beth; Sacaju, Galit; Mathema, Barun; Bifani, Pablo; Kreiswirth, Barry N. // Journal of Infectious Diseases; 8/1/2003, Vol. 188 Issue 3, p356
One multidrug-resistant Mycobacterium tuberculosis (MDRTB) strain, strain W, caused several nosocomial outbreaks in New York City (NYC) during 1 January 1990-31 July 1993. We reviewed all MDRTB cases verified during 1 August 1993-31 December 1999 that had isolates with either this DNA pattern or...