Citations with the tag: CHALCONES

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  • Synthesis of Chalcones with Anticancer Activities.
    Syam, Suvitha; Abdelwahab, Siddig Ibrahim; Al-Mamary, Mohammed Ali; Mohan, Syam // Molecules; Jun2012, Vol. 17 Issue 6, p6179 

    Several chalcones were synthesized and their in vitro cytotoxicity against various human cell lines, including human breast adenocarcinoma cell line MCF-7, human lung adenocarcinoma cell line A549, human prostate cancer cell line PC3, human adenocarcinoma cell line HT-29 (colorectal cancer) and...

  • A new alternative to methyl bromide.
    WILBANKS, JOHNATHAN // California Farmer; Dec2012, Vol. 295 Issue 12, p10 

    The article reports on chalcones, an organic compound that could be an alternative pesticide for methyl bromide developed by Dr. Saeed Attar and professor Alejandro Calderón-Urrea. INSET: Key Points.

  • Kinetics and Mechanism of Oxidation of Chalcones by 1,3-Dichloro-5,5-dimethyl Hydantoin.
    SELVI, P. TAMIL; KARUNAKARAN, K. // Asian Journal of Chemistry; 2015, Vol. 27 Issue 5, p1725 

    Mechanistic study on oxidation of chalcone by 1,3-dichloro-5,5-dimethyl hydantoin (DCDMH or DCH) in aqueous acetic acid medium have been carried out. The reaction follows a fractional order (0.63) with respect to substrate and first order with respect to the oxidant. Increase in percentage of...

  • Discovery of the molecular mechanisms of the novel chalcone-based Magnaporthe oryzae inhibitor C1 using transcriptomic profiling and co-expression network analysis.
    Chen, Hui; Wang, Xiaoyun; Jin, Hong; Liu, Rui; Hou, Taiping // SpringerPlus; 10/22/2016, Vol. 5 Issue 1, p1 

    Background: In our previous studies, we discovered a series of chalcone-based phytopathogenic fungus inhibitors. However, knowledge of their effects, detailed targets and molecular mechanisms in Magnaporthe oryzae ( M. oryzae) remained limited. Methods: To explore the expression and function of...

    Chowrasia, Deepak; Sharma, Nisha; Chaurasia, Anand; Bharti, Adidev; Pratap, Anil // Pharmacophore; Sep/Oct2016, Vol. 7 Issue 5, p5 

    Chalcones/1,3-diphenyl-2-propene-1-one/benzalacetophenone, are the name of structurally related same compound containing two aromatic rings conjunct via bridge system enveloping carbon and keto-ethylenic moiety, considered to be precursors of bioactive flavonoids and isoflavonoids. The molecule...

  • Reduções estereosseletivas de chalconas utilizando biocatalisador – Daucus carota.
    Silva, Wender A.; Melo, Lennine R.; Pedreira, Júlia G. B.; Oliveira, Guilherme R. // Orbital: The Electronic Journal of Chemistry; Apr2012 Supplement, Vol. 4, p76 

    No abstract available.

  • A New Chalcone Glycoside from Combretum griffithii.
    Wang, Liqin; Wu, Mingmei; Wang, Jihua; Jiang, Jinhe; Chen, Yegao; Li, Ting // Chemistry of Natural Compounds; May2014, Vol. 50 Issue 2, p258 

    A new chalcone glycoside, 2′,4,4′,6′-tetrahydroxydihydrochalcone 2′-O-α-L-rhamnopyranosyl-(1 → 6)-β-Dglucopyranoside ( 1), was isolated from Combretum griffithii Huerck et M.-A. along with the known compounds (-)-epigallocatechin ( 2),...

  • Qumai Total Flavonoids Induced Diabetic Mice Model of Streptozotocin.
    Mingsan Miao; Bolin Cheng; Na Jiang; Meiqiong Jiang // Applied Mechanics & Materials; 2014, Issue 664, p410 

    Purpose: Research Qumai total flavonoids induced diabetic mice model of streptozotocin. Methods: 12 h after fasting groups of mice, Tail vein injection of citrate buffer chain urea with cephalosporins solution (80mg/kg, 0.02ml/10g), To 1 times a day. In dosing 10, 20, 30 days tail blood glucose...

  • Structure-Activity Association of Flavonoids in Lung Diseases.
    Lago, João Henrique G.; Toledo-Arruda, Alessandra C.; Mernak, Márcia; Barrosa, Kaidu H.; Martins, Milton A.; Tibério, Iolanda F. L. C.; Prado, Carla M. // Molecules; Mar2014, Vol. 19 Issue 3, p3570 

    Flavonoids are polyphenolic compounds classified into flavonols, flavones, flavanones, isoflavones, catechins, anthocyanidins, and chalcones according to their chemical structures. They are abundantly found in Nature and over 8,000 flavonoids have from different sources, mainly plant materials,...

  • Analogs of Natural 3-Deoxyanthocyanins: O-Glucosides of the 4',7-Dihydroxyflavylium Ion and the Deep Influence of Glycosidation on Color.
    Basílio, Nuno; Al Bittar, Sheiraz; Mora, Nathalie; Dangles, Olivier; Pina, Fernando // International Journal of Molecular Sciences; Oct2016, Vol. 17 Issue 10, p1 

    3-Deoxyanthocyanidins and their O-β-D-glucosides are natural pigments abundant in black sorghum. O-glycosidation can perturb the acid-base properties of the chromophore and lower its electron density with a large impact on the distribution of colored and colorless forms in aqueous solution....

  • Synthesis, Characterization of Chalcone Containing Methacrylate Polymers: Investigation of Fluorescence, Thermal and Dielectric Properties.
    Coşkun, Mehmet Fatih; Şentürk, Adem; Coşkun, Demet // Afyon Kocatepe University Journal of Science & Engineering; 2016, Vol. 16 Issue 2, p230 

    No abstract available.

    Ameta, K. L.; Rathore, Nitu S.; Kumar, Biresh // Analele Universitatii Bucuresti: Chimie; 2011, Vol. 20 Issue 1, p15 

    A facile synthesis of some novel chalcones (3a-3k) by the condensation of variously substituted aromatic aldehydes and 2,4-dihydroxyacetophenone and their subsequent rapid one pot transformations to 2-aminobenzene-1,3-dicarbonitriles (5a-5k) with malononitrile and morpholine has been described....

  • Multicomponent reaction for the synthesis of pyridine derivatives based on triphenylamine.
    Geng, Li-Jun; Feng, Guo-Liang; Yu, Jiu-Gao; Zhang, Hong-Li // Journal of Chemical Research; 2011, Vol. 35 Issue 2, p74 

    A facile preparation of pyridine derivatives based on triphenylamine through a multicomponent reaction from 3-cyanoacetylindoles, ammonium acetate and a 1,3-diarylpropenone either by conventional heating or microwave irradiation is described. The three-component reaction afforded good yields and...

  • Synthesis of ferrocenyl chalcones of the abietane series.
    Glushkov, V.; Anikina, L.; Maiorova, O.; Nedugov, A.; Slepukhin, P. // Russian Journal of Organic Chemistry; Jun2012, Vol. 48 Issue 6, p836 

    Two isomeric ferrocenyl chalcones having an abietane fragment were synthesized.

  • Topological Investingation and Modeling of Antimalarial Activity of Chalcone.
    Dwivedi, Sudhanshu Dhar; Bharadwaj, Arpan; Ghuraiya, Anis; Shrivastava, Amit // International Journal of ChemTech Research; Apr-Jun2012, Vol. 4 Issue 2, p662 

    A set of chalcone derivatives were tested for their antimalarial activities¹. Quantitative structure activity relationship (QSAR) analysis was applied to forty-two of the abovementioned derivatives using a combination of various topological descriptors. A multiple linear regression (MLR)...

  • Synthesis of Side Chain Chalcone Polymers and Their Photoalignment Capability for Film Patterned Retarder.
    Ju Hui Kang; Seung Yong Jeong; Sangkug Lee; Kyung Ho Choi; Gyo jic Shin // International Proceedings of Chemical, Biological & Environmenta; 2012, Vol. 43, p67 

    We synthesized two kinds of photocrosslinkable side chain photopolymer with a chalcone group in the side chain. Two photopolymers have the different alkyl spacer length introduced between main chain and chalconyl moiety. The thermal stability of these photopolymer measured by differential...

  • Synthesis of some novel Isoxazole, Cyanopyridine and Pyrimidinthione derivatives.
    Solankee, N.; Patel, K. P.; Patel, R. B. // Journal of Chemical & Pharmaceutical Research; 2012, Vol. 4 Issue 8, p3778 

    A new series of isoxazoles (7a-d), cyanopyridines (8a-d) and pyrimidinthiones (9a-d) have been prepared from chalcones (6a-d) having s-triazine nucleus. These chalcones on cyclisation with hydroxyl amine hydrochloride in the presence of alkali and malononitrile in the presence of ammonium...

  • Antimicrobial activities of synthesized and characterized 5-acetyl pyrimidine-2, 4, 6-(1H, 3H, 5H)-trione based chalcones.
    Dhorajiya, Bhavesh D.; Malani, Mahesh H.; Patel, Jigar R.; Dholakiya, Bharat Z. // Der Pharma Chemica; 2012, Vol. 4 Issue 1, p141 

    A series of eleven 5-((E)-3-phenylacryloyl) pyrimidine-2, 4, 6-(1H, 3H, 5H)-triones (5-acetyl pyrimidine 2, 4, 6-(1H, 3H, 5H) trione based chalcone) were synthesized using diethylmalonate, urea, acetic anhydride and various aryl aldehydes under basic conditions afforded the 5-acetyl...

  • Evaluation of Silica-H2SO4 as an Efficient Heterogeneous Catalyst for the Synthesis of Chalcones.
    Sultan, Aeysha; Raza, Abdul Rauf; Abbas, Muhammad; Khan, Khalid Mohammed; Tahir, Muhammad Nawaz; Saari, Nazamid // Molecules; Aug2013, Vol. 18 Issue 8, p10081 

    We report an efficient silica-H2SO4 mediated synthesis of a variety of chalcones that afforded the targeted compounds in very good yield compared to base catalyzed solvent free conditions as well as acid or base catalyzed refluxing conditions.

  • Synthesis and Antioxidant Activity of Some Chalcones and Flavanoids.
    Yogesh Murti; Ashish Goswami; Pradeep Mishra // International Journal of PharmTech Research; Apr-Jun2013, Vol. 5 Issue 2, p811 

    In the present work we report the reaction of 2,4-dihydroxy acetophenone with different substituted aromatic aldehyde to form 2,4-dihydroxy chalcones. Various analogues of 7-hydroxy flavanoids were reported by oxidative cyclization of 2,4-dihydroxy chalcones. The structure of the newly...

  • Improved microwave-induced synthesis of indolyl chalcones.
    Pal, Rammohan; Sarkar, Taradas; Sarkar, Tapas // Archives of Applied Science Research; 2014, Vol. 6 Issue 3, p138 

    Various indolyl chalcones have been synthesized in unsealed vessels in a domestic microwave oven. Considerable increase in the reaction rate has been observed with better yields.

    Pal, Rammohan; Sarkar, Taradas; Sarkar, Tapas // Asian Journal of Research in Chemistry; Feb2011, Vol. 4 Issue 2, p3 

    The article presents abstracts on medical topics including latest strategy of medicinal chemistry implements, synthesis and anti-microbial evaluation of chalcone derivatives and synthesis of Copper (II) complexes of Tetradentate Binucleating Schiff Base Ligands.

  • Synthesis And Biological Evaluation of Different Thiazine Derivatives.
    Keerthi kumar, B.; Varalakshmi Devi, K.; Ramesh gupta, P.; Kranthi, G.; Ramakrishna, C.; Sankaraiah, P.; Kumar, Chitta Suresh // Journal of Pharmacy Research; Jan2011, Vol. 4 Issue 1, p274 

    A series of novel chalcones were prepared by the reaction of different benzaldehydes with various Acetophenones and subsequent treatment with thiourea resulted in the formation of corresponding thiazines in good yields. All the new compounds have been characterized by IR, ¹H NMR, MS and...

  • Synthesis and Biological Activity of Heterocycles from Chalcone.
    Al-Ghulikah, H. A. // Asian Journal of Chemistry; 2012, Vol. 24 Issue 4, p1631 

    The reaction between aromatic or heteroaromatic ortho-diamines and chalcone 1a,b is a convenient and versatile method for the preparation of condensed 1,4-diazepines 2a,b and 4a,b. 2,4-Diaryl-2,3-dihydro[1,5]benzothiazepines 5a,b were obtained from the condensation of chalcone 1a,b with...

  • Synthesis and pharmacological screening of some novel chloro chalconesemicarbazone derivatives.
    Singh, Hemendra Pratap; Chauhan, C. S.; Pandeya, S. N.; Sharma, C. S.; Srivastava, B.; Singhal, Manmohan // Der Pharma Chemica; 2010, Vol. 2 Issue 3, p343 

    A series of chalconyl derivatives of chloro phenyl semicarbazide (CA1-CA5) was synthesized. All the synthesized compounds were screened for their pharmacological action in protection of seizures, behavioral study, anti-inflammatory and analgesic activity. After intraperitoneal injection to mice...

  • Formation of 3,4,5,6-tetrahydroquinazolin-2(1 H)-one derivatives in reaction of 4-aryl-6-methyl-3,4-dihydro-pyrimidin-2(1 H)-ones with chalcones.
    Kolosov, M.; Kulyk, O.; Starchenko, O.; Orlov, V. // Chemistry of Heterocyclic Compounds; Nov2013, Vol. 49 Issue 8, p1166 

    A procedure for the preparation of 6-methyl-3,4-dihydropyrimidin-2(1 H)-ones involving deacylation of 5-acetyl-6-methyl-3,4-dihydropyrimidin-2(1 H)-ones in MeOH-KOH medium is developed. We have shown that the obtained compounds readily undergo reaction with chalcones in MeOH-MeONa with the...

  • Synthesis and Biological Evaluation of Some New 2,4,6-Trisubstituted Pyrimidines.
    Sridhar, S.; Prasad, Y. Rajendra; Dinda, S. C. // Asian Journal of Chemistry; 2012, Vol. 24 Issue 3, p1130 

    In the present study, 3-acetyl-2,5-dimethylfuran on condensation with various aromatic and heterocyclic aldehydes in ethanolic KOH solution yielded the corresponding chalcones (3a-n). These chalcones were reacted with guanidine hydrochloride in presence of potassium hydroxide and ethanol to give...

  • Evaluation of the Anti-Inflammatory Effect of Chalcone and Chalcone Analogues in a Zebrafish Model.
    Yau-Hung Chen; Wei-Hua Wang; Yun-Hsin Wang; Zi-Yu Lin; Chi-Chung Wen; Ching-Yuh Chern // Molecules; Feb2013, Vol. 18 Issue 2, p2052 

    The aim of this study was to investigate novel chalcones with potent anti-inflammatory activities in vivo. Chalcone and two chalcone analogues (compound 5 and 9) were evaluated using a caudal fin-wounded transgenic zebrafish line "Tg(mpx:gfp)" to visualize the effect of neutrophil recruitment...

  • Synthesis, Antibacterial and Antifungal Activity of Some New Pyrazoline and Pyrazole Derivatives.
    Hassan, Seham Y. // Molecules; Mar2013, Vol. 18 Issue 3, p2683 

    A series of 2-pyrazolines 5-9 have been synthesized from α,β-unsaturated ketones 2-4. New 2-pyrazoline derivatives 13-15 bearing benzenesulfonamide moieties were then synthesized by condensing the appropriate chalcones 2-4 with 4-hydrazinyl benzenesulfonamide hydrochloride. Ethyl [1,2,4]...

  • Synthesis and antibacterial activity of some new thiazine derivatives.
    Deepika, G.; Gopinath, P.; Kranthi, G.; Nagamani, C.; Jayasree Yadav, V.; Naidu, N.V.; Enaganti, Sreenivas // Journal of Pharmacy Research; 2012, Vol. 5 Issue 2, p1105 

    A series of novel chalcones were prepared by the reaction of different benzalaldehyde with various propiophenone and subsequent treatment with thiourea resulted in the formation of corresponding thiazines in good yields. All the new compounds have been characterized by IR and 1H-NMR spectral...

  • Chalcones: compounds possessing a diversity in applications.
    Urmila Berar // Orbital: The Electronic Journal of Chemistry; Jul-Sep2012, Vol. 4 Issue 3, p209 

    Chalcones are a class of α,β-unsaturated carbonyl compounds that form the central core for a variety of naturally occurring biologically active compounds. They exhibit tremendous potential to act as a pharmacological agent. Besides their various pharmacological activities, chalcones have...

  • Microwave assisted synthesis of novel methylenebis{2-[(1-benzyl/cyclohexyl-1 H-1,2,3-triazol-4-yl)methoxy]chalcones} and their antibacterial activity.
    Ramesh, S.; Ashok, D.; Linga Goud, G.; Prabhakar Reddy, V. // Russian Journal of General Chemistry; Aug2014, Vol. 84 Issue 8, p1608 

    A series of novel methylenebis{2-[(1-benzyl/cyclohexyl-1 H-1,2,3-triazol-4-yl)methoxy]chalcones} ( IVa-IVn) have been synthesized by the Click reaction and Claisen-Schmidt condensation of 5,5′-methylenebis[2-(prop-2-yn-1-yloxy)benzaldehyde] under microwave irradiation with high yields. All...

  • Synthesis, Leishmanicidal and Cytotoxic Activity of Triclosan-Chalcone, Triclosan-Chromone and Triclosan-Coumarin Hybrids.
    Otero, Elver; Vergara, Sebastián; Robledo, Sara M.; Cardona, Wilson; Carda, Miguel; Vélez, Ivan D.; Rojas, Carlos; Otálvaro, Felipe // Molecules; Sep2014, Vol. 19 Issue 9, p13251 

    Twelve hybrids derived from triclosan were obtained via Williamson etherification of O-triclosan alkyl bromide plus chalcone and O-coumarin or O-chromone alkyl bromide plus triclosan, respectively. Structures of the products were elucidated by spectroscopic analysis. The synthesized compounds...

  • Application of the Suzuki-Miyaura Reaction in the Synthesis of Flavonoids.
    Selepe, Mamoalosi A.; Van Heerden, Fanie R. // Molecules; Apr2013, Vol. 18 Issue 4, p4739 

    The application of the Suzuki-Miyaura reaction in the synthesis of flavonoids, an important class of natural products, is reviewed. This reaction has not only been employed to provide access to flavonoid nuclei, but has also been applied to the synthesis of dimeric flavonoids and in the...

  • Microwave-assisted Michael addition of 2-amino pyridine to chalcones under catalyst-free conditions.
    Zhao, Bing; Jiang, Lili; Liu, Zhuo; Deng, Qigang; Wang, Liyan; Song, Bo; Gao, Yan // Research on Chemical Intermediates; Aug2015, Vol. 41 Issue 8, p5809 

    A microwave-assisted, convenient, efficient, and catalyst-free procedure is described for the synthesis of 1,3-diphenyl-3-(pyridin-2-ylamino)propan-1-one derivatives by Michael addition of 2-aminopyridine to the chalcones. Short reaction times, simple reaction, easy of product isolation, high...

  • Synthesis and Characterization of Spirochromanoid Chalcone Derivatives.
    Dawale, J. K.; Bondge, A. S.; Tripathi, P. K.; Krishnan, M. M. // Asian Journal of Research in Chemistry; Aug2011, Vol. 4 Issue 8, p1281 

    The chalcone derivatives of spirochromanoid frame have been synthesized starting from resorcinol. It is converted in to the spirochomanone protected by N-Boc-4-piperidone.the chalcones of this spirochromanone are synthesized by Claisen Schmidt condensation reacting with 2-chloro benzaldehyde,...

  • Microwave Assisted Synthesis, Spectral Studies and Antibacterial Activity of 1, 5-benzodiazepines Derivatives on a Solid Surface.
    DEVPURA, ANJU; SINGH, JAYANT P.; JAITAWAT, NEETU; RATHORE, RENU; KUMAWAT, MONIKA; DULAWAT, SHIV S. // Asian Journal of Chemistry; 2012, Vol. 24 Issue 12, p5914 

    Chalcones are well known intermediates for synthesizing various heterocyclic compounds. They have been utilized for the synthesis of various substituted benzodiazepines by the reaction of o-phenylenediamine. In present investigation we have carried out the reaction under both conventional method...

  • Synthesis and Antibacterial Studies of Chloro-Substituted 1,3-Thiazines.
    RAJPUT, P. R.; GAJBHIYE, A. V.; BHADE, M. W. // Asian Journal of Chemistry; 2012, Vol. 24 Issue 12, p5699 

    Thiazines are very useful units in the fields of medicinal and pharmaceutical chemistry and have been reported to exhibit a variety of biological activities. This has directed us to synthesize chloro-substituted thiazines from 2'-hydroxy-3',5'-dichloro-4-4'-chlorophenyl chalcone with thiourea,...

  • Microwave Assisted Synthesis and Antibacterial Activity of Chalcone Derivatives.
    YADAV, KHUSHBU; SHARMA, ABHA; SRIVASTAVA, J. N. // Asian Journal of Chemistry; 2012, Vol. 24 Issue 12, p5779 

    Chalcone derivatives have been synthesized by equimolar reactions between substituted aldehydes and substituted acetophenones in basic medium by using conventional and microwave assisted technique. These compounds are characterized by FTIR and ¹H NMR spectra. Before characterization purity of...

  • Synthesis, Electrochemical, and Thermal Properties of [3]Ferrocenophane-Containing Chalcone Derivatives.
    Haiying Zhao; Xueyou Zhu; Dong Wang; Shufeng Chen; Zhanxi Bian // Australian Journal of Chemistry; 2015, Vol. 68 Issue 7, p1035 

    [3]Ferrocenophane-containing chalcone derivatives with benzene ring (3a-3d) or naphthalene ring (3e-3f) were synthesized and characterized. The potentials for [3]ferrocenophane-containing chalcones cathodically shifted ~70-80mV compared with those of ferrocene-containing chalcones, indicating...

  • Phase Transfer Catalysis Extends The Scope of The Algar-Flynn-Oyamada Synthesis of 3-Hydroxyflavones.
    Nhu, Duong; Hawkins, Bill C.; Burns, Christopher J. // Australian Journal of Chemistry; 2015, Vol. 68 Issue 7, p1102 

    The Algar-Flynn-Oyamada reaction is the classical method to synthesize 3-hydroxyflavones from chalcones. Despite its relative simplicity, the reaction has several drawbacks including variable and often low product yields. We have found that phase transfer catalysis improves the yields and...

  • Role of a chalcone isomerase-like protein in flavonoid biosynthesis in Arabidopsis thaliana.
    Wenbo Jiang; Qinggang Yin; Ranran Wu; Guangshun Zheng; Jinyue Liu; Dixon, Richard A.; Yongzhen Pang // Journal of Experimental Botany; Dec2015, Vol. 66 Issue 22, p7165 

    Flavonoids are important natural products for plant defence and human health. Although almost all the flavonoid pathway genes have been well-documented by biochemical and/or genetic approaches, the role of the Arabidopsis chalcone isomerase-like (CHIL) gene remains unclear. Two chil mutants with...

  • Synthetic protocols on 6H-benzo[c]chromen-6-ones: a review.
    MAZIMBA, Ofentse // Turkish Journal of Chemistry; 2016, Vol. 40 Issue 1, p1 

    6H-Benzo[c]chromen-6-ones serve as core structures of secondary metabolites and are of considerable pharmacological importance. Natural sources produce limited quantities, hence the need for synthetic procedures for 6H-benzo[c ]chromen-6-ones, which are herein reviewed. The literature describes...

  • A mutation in the rice chalcone isomerase gene causes the golden hull and internode 1 phenotype.
    Hong, Lilan; Qian, Qian; Tang, Ding; Wang, Kejian; Li, Ming; Cheng, Zhukuan // Planta; Jul2012, Vol. 236 Issue 1, p141 

    The biosynthesis of flavonoids, important secondary plant metabolites, has been investigated extensively, but few mutants of genes in this pathway have been identified in rice ( Oryza sativa). The rice gold hull and internode ( gh) mutants exhibit a reddish-brown pigmentation in the hull and...

  • Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs.
    Padhye, Subhash; Ahmad, Aamir; Oswal, Nikhil; Sarkar, Fazlul H. // Journal of Hematology & Oncology; 2009, Vol. 2, p1 

    Garcinol, harvested from Garcinia indica, has traditionally been used in tropical regions and appreciated for centuries; however its biological properties are only beginning to be elucidated. There is ample data to suggest potent antioxidant properties of this compound which have been used to...

  • Characterization and mapping of a QTL derived from Solanum habrochaites associated with elevated rutin content (quercetin-3-rutinoside) in tomato.
    Hanson, Peter; Schafleitner, Roland; Huang, Shu-Mei; Tan, Chee-Wee; Ledesma, Dolores; Yang, Ray-Yu // Euphytica; Dec2014, Vol. 200 Issue 3, p441 

    Consumption of flavonoids found in fruits and vegetables is linked to beneficial health outcomes. Tomato is among the most widely consumed and economically important vegetables worldwide and improvement of the nutrient content could lead to significant health benefits. Rutin,...

  • Synthesis and antimicrobial activity of chalcones containing benzotriazolylmethyl and imidazolylmethyl substituents.
    Chinh, L.; Hung, T.; Nga, N.; Hang, T.; Mai, T.; Tarasevich, V. // Russian Journal of Organic Chemistry; Dec2014, Vol. 50 Issue 12, p1767 

    Methods have been developed for the synthesis of new 1 H-benzotriazol-1-ylmethyl- and 1 H-imidazol-1-ylmethyl-substituted chalcones starting from 2-hydroxyacetophenone. The procedures include chloromethylation, N-alkylation, and Claisen-Schmidt condensation. The presence of an imidazole fragment...

  • A novel synthesis of ( E)-1-(2-hydroxyphenyl)-3-(1 Н-indol-3-yl)- prop-2-en-1-ones from chromone-3-carboxylic acid and indoles.
    Kornev, Mikhail; Moshkin, Vladimir; Sosnovskikh, Vyacheslav // Chemistry of Heterocyclic Compounds; Sep2015, Vol. 51 Issue 9, p858 

    [MediaObject not available: see fulltext.] The reaction of chromone-3-carboxylic acid with indoles in boiling ethanol proceeds as a 1,4-nucleophilic addition with successive opening of the pyrone ring and decarboxylation to afford a series of previously unknown trans-indolyl chalcones in 27-60%...

  • Evaluation of antifungal and cytotoxic activity of trans-Chalcone and α-Solanine.
    Komoto, Tatiana Takahasi; Silva, Gabriel; Bitencourt, Tamires; Cestari, Bruna Azevedo; Marins, Mozart; Fachin, Ana Lúcia // BMC Proceedings; 10/1/2014, p1 

    An abstract of the article "Evaluation of antifungal and cytotoxic activity of trans-Chalcone and α-Solanine" by Tatiana Takahasi Komoto and colleagues is presented.

  • Effect of chalcones in the modulation of Trichophyton rubrum cell wall synthesis genes.
    Bittencourt, Tamires Ap.; Martins, Juliana Simões; Abreu, Mariana; Komoto, Tatiana; Bortolotto, Luiz Felipe; Crivelenti, Yasmim; Mesquita, Thais; Pinhanelli, Vitor; Cantelli, Bruna; Marins, Mozart; Fachin, Ana Lucia // BMC Proceedings; 10/1/2014, p1 

    An abstract of the article "Effect of chalcones in the modulation of Trichophyton rubrum cell wall synthesis genes" by Vitor Pinhanelli is presented.

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