Citations with the tag: CELL nuclei -- Transplantation
Results 1 - 50
- Hello Dolly.
Bronson, Rebecca; Kowalski, Kathiann M. // Odyssey; Feb98, Vol. 7 Issue 2, p12
Explains how nuclear transfer was used to clone sheep. Differentiation of the cells; German scientist Hans Spemann's discovery of cells directing development of a normal embryo; Mammals in vitro fertilization; Implantation into a surrogate mother; Use of a nucleus from an adult in cloning sheep.
- Progress in Human Somatic-Cell Nuclear Transfer.
Bronson, Rebecca; Kowalski, Kathiann M. // New England Journal of Medicine; 7/27/2006, Vol. 355 Issue 4, p429
A correction to the article "Progress in Human Somatic-Cell Nuclear Transfer," in the July 7, 2005 issue is presented.
- Genetic Manipulation by Nuclear Transfer.
Bronson, Rebecca; Kowalski, Kathiann M. // Journal of Assisted Reproduction & Genetics; Sep97, Vol. 14 Issue 8, p480
Presents an abstract if the article `Genetic Manipulation by Nuclear Transfer,' by Don P. Wolf, which was presented at the Second International Symposium on Preimplantation Genetics.
- nuclear transplantation:.
Schlegel, Rolf H. J. // Encyclopedic Dictionary of Plant Breeding & Related Subjects; 2003, p292
A definition of the term "nuclear transplantation" is presented which refers to the transfer of a nucleus into the cytoplasm of another cell.
- Distinct functions for the two importing subunits in nuclear protein import.
Gorlich, Dirk; Vogel, Frank // Nature; 9/21/1995, Vol. 377 Issue 6546, p246
Illustrates how the import of nuclear proteins proceeds through the nuclear pore complex requiring nuclear localization signals, energy and soluble factors. Role of importin-alpha and importin-beta as import substrate; Efficiency of import using recombinant soluble factors.
- Lambing by nuclear transfer.
Solter, Davor // Nature; 3/7/1996, Vol. 380 Issue 6569, p24
Explains why the successful cloning of identical sheep by nuclear transfer from cultured cells is cause for celebration. Experiments to increase understanding of the genetic control of mammalian development have only been successful in mice historically; Limitations of reliable nuclear transfer...
- Sheep cloned by nuclear transfer from a cultured cell line.
Campbell, K.H.S.; McWhir, J. // Nature; 3/7/1996, Vol. 380 Issue 6569, p64
Presents the first report ever of live mammalian offspring following nuclear transfer from an established cell line. Details of the processes which culminated in the successful cloning of sheep; Implications of the findings.
- Contemporary ethical analyses: A shortfall in scientific knowledge.
Bacchetta, Matthew; Richter, Gerd // Politics & the Life Sciences; Mar98, Vol. 17 Issue 1, p11
Opinion. Comments on Andrea Bonnicksen's views on issues pertaining to nuclei transplantation between eggs. Limitations of scientific knowledge on issues pertaining to nuclei transplantation; Details on the complexities of medical science; Reference to some of the major issues concerning medicine.
- Researchers and their subjects as neighbors.
Lachs, John // Politics & the Life Sciences; Mar98, Vol. 17 Issue 1, p24
Focuses on issues pertaining to genetic modification, with emphasis on egg cell nuclear transfer. Factors which influence the success of science; Details on the pursuit of goals in science; Analysis of ethical problems and policy options in science.
- The 'New' Genetics and Mammalian Cloning in Environmental Health Research.
Iannaccone, Philip M. // Environmental Health Perspectives; Oct2000, Vol. 108 Issue 10, pA438
Editorial. Comments on the importance of genetic technology on the study of toxicology. Relevance of toxicological studies on the application of transgenic mice and knock-out technologies; Enhancement of rat models through mammalian cloning; Key steps in base excision repair; Concept of...
- ANT vs. SCNT.
Insoo Hyun; Kyu Won Jung // Hastings Center Report; Nov/Dec2006, Vol. 36 Issue 6, p6
A letter to the editor is presented in response to the article "Seeking Consensus: A Clarification and Defense of Altered Nuclear Transfer," in the September-October 2006 issue.
- ANT vs. SCNT.
Hurlbut, William B.; George, Robert P.; Grompe, Markus // Hastings Center Report; Nov/Dec2006, Vol. 36 Issue 6, p7
A letter to the editor is presented in response to comments on the article regarding nuclear transfer in the September-October 2006 issue.
- Donation of fresh oocytes for nuclear transfer research -- a new approach.
Choudhary, M.; Nesbitt, M.; Leary, C.; Murdoch, A. P. // Reproductive BioMedicine Online; Aug2006, Vol. 13 Issue 2, p301
A letter to the editor is presented in response to an article about the donation of human oocytes for nuclear transfer research.
- 746. Evaluation of Nuclear Transfer and Transcription of Plasmid DNA Condensed with Protamine.
Masuda, Tomoya; Akita, Hidetaka; Harashima, Hideyoshi // Molecular Therapy; Jun2005, Vol. 11, p289
An abstract of article "Evaluation of Nuclear Transfer and Transcription of Plasmid DNA Condensed with Protamine," by Tomoya Masuda, Hidetaka Akita and Hideyoshi Harashima is presented.
- Experiment reveals deficits in European regulation.
Bosch, Xavier // Nature Medicine; Jun2000, Vol. 6 Issue 6, p609
Focuses on the investigation into a research involving human oocyte nuclear transfer without permission in Spain. Differences in the regulation of human fertility experimentation across Europe; Infringement of law; Scientist's demand for a public apology from the Commission on Assisted...
- Somatic cell nuclear transfer.
Wilmut, I.; Beaujean, N.; de Sousa, P. A.; Dinnyes, A.; King, T. J.; Paterson, L. A.; Wells, D. N.; Young, L. E. // Nature; 10/10/2002, Vol. 419 Issue 6907, p583
Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.
- Morally Healthy Cells.
Kutz, Lawrence A. // First Things: A Monthly Journal of Religion & Public Life; Aug/Sep2005, Issue 155, p7
Presents a letter to the editor in response to an article about altered nuclear transfer, which appeared in the March 2005 issue.
- Morally Healthy Cells.
Buckley, Don W. // First Things: A Monthly Journal of Religion & Public Life; Aug/Sep2005, Issue 155, p7
Presents a letter to the editor commenting on an article about altered nuclear transfer, which appeared in the March 2005 issue.
- Attack of the fish clones.
Murphey, Ryan D.; Zon, Leonard I. // Nature Biotechnology; Aug2002, Vol. 20 Issue 8, p785
Reports on a study by Shuo Lin, et al, in the February 2002 issue of 'Nature Biotechnology' on nuclear transfer in zebrafish using long-term cultured donor cells. Implications of the study for gene targeting in fish; Targeting strategy used in Drosophila melanogaster to produce homologous...
- Deletion of the a(1,3)galactosyl transferase (GGTA1) gene and the prion protein (PrP) gene in sheep.
Denning, C.; Burl, S.; Ainslie, A.; Bracken, J.; Dinnyes, A.; Fletcher, J.; King, T.; Ritchie, M.; Ritchie, W. A.; Rollo, M.; de Sousa, P.; Travers, A.; Wilmut, I.; Clark, A. J. // Nature Biotechnology; Jun2001, Vol. 19 Issue 6, p559
Nuclear transfer offers a cell-based route for producing precise genetic modifications in a range of animal species. Using sheep, we report reproducible targeted gene deletion at two independent loci in fetal fibro-blasts. Vital regions were deleted from the a(1,3)galactosyl transferase (GGTA1)...
- Altered Nuclear Transfer.
Hurlbut, William B. // New England Journal of Medicine; 3/17/2005, Vol. 352 Issue 11, p1153
A letter to the editor is presented in response to an article by Douglas A. Melton and colleagues about altered nuclear transfer, which appeared in the December 30, 2004 issue.
- Altered Nuclear Transfer.
Melton, Douglas A.; Daley, George Q.; Jennings, Charles G. // New England Journal of Medicine; 3/17/2005, Vol. 352 Issue 11, p1153
A response by Douglas A. Melton and colleagues to a letter to the editor about their article concerning altered nuclear transfer, which appeared in the December 30, 2004 issue, is presented.
- Nuclear transport: Hikeshi 'puts out the fire' in the nucleus.
David, Rachel // Nature Reviews Molecular Cell Biology; Jun2012, Vol. 13 Issue 6, p341
The article discusses a study on the potential of a conserved protein as a protein carrier of HSP70.
- Unilateral transplantation of human primary fetal tissue in four patients with Huntington?s disease: NEST-UK safety report ISRCTN no 36485475.
A E Rosser // Journal of Neurology, Neurosurgery & Psychiatry; Dec2002, Vol. 73 Issue 6, p678
OBJECTIVES: Huntington?s disease (HD) is an inherited autosomal dominant condition in which there is a CAG repeat expansion in the huntingtin gene of 36 or more. Patients display progressive motor, cognitive, and behavioural deterioration associated with progressive cell loss and atrophy in the...
- Some conceptual and ethical comments on egg cell nuclear transfer.
Graumann, Sigrid; Haker, Hille // Politics & the Life Sciences; Mar98, Vol. 17 Issue 1, p17
Comments on issues pertaining to egg cell nuclear transfer. Details on the contraction of rare genetic diseases; Benefits of egg cell nuclear transfer; Comparison of egg cell nuclear transfer and nuclear deoxyribonucleic acid (DNA); Information on DNA transcription.
- Identity, integrity, and nuclei transplantation.
Holtug, Nils // Politics & the Life Sciences; Mar98, Vol. 17 Issue 1, p20
Comments on the article entitled `Transplanting Nuclei between Human Eggs: Implications for Germ-Line Genetics,' which pertains to nuclei transplantation and germ-line therapy. Comparison between germ-line therapy and nuclei transplantation; Reference to individuals' opposition to germ-line...
- Nuclear meltdown: Ethics of the need to transfer genes.
McGee, Glenn; McGee, Daniel B. // Politics & the Life Sciences; Mar98, Vol. 17 Issue 1, p26
Looks at issues pertaining to reproductive medicine, while highlighting the transfer of cell nuclei. Information on developments in nuclear transplantation technologies; Importance of nuclei transfer; Factors which influence the development of transplantation technology.
- Genetic engineering of human eggs and embryos: Prelude to cloning.
Warner, Carol M. // Politics & the Life Sciences; Mar98, Vol. 17 Issue 1, p33
Comments on the article written by Andrea Bonnicksen, which pertains to the nuclear transfer of human egg cell nuclei. Description of benefits associated with nuclear transfer of egg cell nuclei; How nuclear transfer can be used to cure mitochondrial disease; Reference to other methods which can...
- A welcome alert to backdoor germ-line therapy.
Rose, Hilary // Politics & the Life Sciences; Mar98, Vol. 17 Issue 1, p34
Offers the author's criticism of an article written by Andrea Bonnicksen, which pertains to cell nuclei transplantation and its role in the treatment and cure of mitochondrial diseases. Reference to studies conducted on cell nuclei transfer; Details on the application of germ-line therapy.
- Creation of hybrid vigor through nuclear transplantation in Phytophthora.
Gu, Yu-Huan; Ko, Wen-Hsiung // Canadian Journal of Microbiology; Jul2001, Vol. 47 Issue 7, p662
When isolated nuclei of a diploid oomycete, Phytophthora parasitica, were fused with protoplasts of another strain of the same species, the regenerated nuclear hybrids grew faster than the parental isolates. Such a phenomenon did not occur in hybrids regenerated from mitochondrion�protoplast...
- Oocyte-induced haploidization.
Palermo, Gianpiero D.; Takeuchi, Takumi; Rosenwaks, Zev // Reproductive BioMedicine Online; May/Jun2002, Vol. 4 Issue 3, p237
Describes the approach to treatment of age-related oocyte aneuploidy. Approaches in aneuploidy prevention; Results from nuclear transplantation of mouse and human oocytes; Sources of oocytes.
- Proliferative lifespan is conserved after nuclear transfer.
Clark, A. John; Ferrier, Patricia; Aslam, Samena; Burl, Sarah; Denning, Chris; Wylie, Diana; Ross, Arlene; de Sousa, Paul; Wilmut, Ian; Cui, Wei // Nature Cell Biology; Jun2003, Vol. 5 Issue 6, p535
Cultured primary cells exhibit a finite proliferative lifespan, termed the Hayflick limit[SUP1]. Cloning by nuclear transfer can reverse this cellular ageing process and can be accomplished with cultured cells nearing senescence[SUP2]. Here we describe nuclear transfer experiments in which donor...
- Nuclear transport erupts on the slopes of Mount Etna.
Dasso, Mary; Powers, Maureen A. // Nature Cell Biology; Feb2004, Vol. 6 Issue 2, p82
Nuclear pore complexes (NPCs) mediate the active transport of large substrates and allow the passive diffusion of small molecules into the nucleus of eukaryotic cells. The EMBO Workshop on the Mechanisms of Nuclear Transport focused on NPCs and on the soluble nucleocytoplasmic transport...
- Mitochondrial DNA genotypes in nuclear transfer-derived cloned sheep.
Evans, Matthew J.; Gurer, Cagan; Loike, John D.; Wilmut, Ian; Schnieke, Angelika E.; Schon, Eric A. // Nature Genetics; Sep99, Vol. 23 Issue 1, p90
Eukaryotic cells contain two distinct genomes. One is located in the nucleus (nDNA) and is transmitted in a mendelian fashion, whereas the other is located in mitochondria (mtDNA) and is transmitted by maternal inheritance. Cloning of mammals typically has been achieved via nuclear transfer, in...
- Genetic rescue of an endangered mammal by cross-species nuclear transfer using post-mortem somatic cells.
Loi, Pasqualino; Ptak, Grazyna; Barboni, Barbara; Fulka, Josef; Cappai, Pietro; Clinton, Michael // Nature Biotechnology; Oct2001, Vol. 19 Issue 10, p962
Since the advent of procedures for cloning animals, conservation biologists have proposed using this technology to preserve endangered mammals. Here we report the successful cloning of a wild endangered animal, avis orientalis musimon, using oocytes collected from a closely related, domesticated...
- New regulations give UK the lead in stem cell work.
Dickson, David // Nature Medicine; Apr2002, Vol. 8 Issue 4, p315
Focuses on the regulations permitting research on embryonic stem (ES) cells and cells derived by nuclear transfer in Great Britain. Provisions of the regulations approved by the government related to research on ES cells; Importance of the research on ES cells; Description of the health...
- Microsurgical cloning techniques for zygotes: a long-term dispute.
Illmensee, Karl // Reproductive BioMedicine Online (Reproductive Healthcare Limited; Jan2009, Vol. 18 Issue 1, p7
Zygotes (fertilized oocytes) have been considerably neglected as suitable recipients for cell nuclear transfer in cloning. Recently, it has been reported by Polish researchers that microsurgical methods using very thin pipettes for pronuclear removal from mouse zygotes seem to be crucial for...
- Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1.
Grant, Richard P.; Hurt, Ed; Neuhaus, David; Stewart, Murray // Nature Structural Biology; Apr2002, Vol. 9 Issue 4, p247
The vertebrate Tap protein is a member of the NXF family of shuttling transport receptors for nuclear export of mRNA. Tap has a modular structure, and its most C-terminal domain is important for binding to FG repeat-containing nuclear pore proteins (FG-nucleoporins) and is sufficient to mediate...
- Don't mention the 'c' word.
Grant, Richard P.; Hurt, Ed; Neuhaus, David; Stewart, Murray // New Scientist; 2/23/2002, Vol. 173 Issue 2331, p3
Editorial. Comments on the eradication of the word clone in biological science. Replacement of the term therapeutic cloning with nuclear transplantation; Impression regarding the eagerness of scientists to clone human beings; Confusion arising from the change of the term.
- Effect of donor cell age on the efficiency of nuclear transfer in rabbits.
Galat, V.; Lagutina, I.; Mezina, M.; Prokofiev, M.I.; Zakhartchenko, V. // Reproductive BioMedicine Online (Reproductive Healthcare Limited; Jan/Feb2002, Vol. 4 Issue 1, p32
Presents information on a study which evaluated the ability of rabbit fibroblasts of different ages to be reprogrammed following nuclear transfer to aged recipient oocytes. Materials and methodology of the study; Results and discussion of the study.
- Only God can do that? Cloning and genetic engineering test the moral limits of Science.
Shermer, Michael // Skeptic; 1999, Vol. 7 Issue 2, p58
Discusses misunderstandings about science held by critics of cloning. Ethical issues related to cloning and genetic engineering; Technique called somatic cell nuclear transfer; Identical personhood myth; Playing God myth.
- MOLECULAR AND EPIGENETIC STUDY OF H19 GENE IN GOAT (CAPRA HIRCUS).
Lal, S. V.; Singh, S.; Kumari, R.; Kumar, S. // Indian Journal of Animal Research; Mar2012, Vol. 46 Issue 1, p15
Due to the high incidence of abnormalities and the inefficiency of generating goat kids through somatic cell nuclear transfer (SCNT), the development of a model system in goat to investigate potential problems is warranted. In nuclear transfer, where genomic imprinting has been implicated as a...
- A cat cloned by nuclear transplantation.
Taeyoung Shin; Kraemer, Duane; Pryor, Jane; Ling Liu; Rugila, James; Howe, Lisa; Buck, Sandra; Murphy, Keith; Lyons, Leslie; Westhusin, Mark // Nature; 2/21/2002, Vol. 415 Issue 6874, p859
Evaluates the efficiency of cloning of cats by nuclear transplantation. Scientific name of cat; Analysis of feline genetic markers; Processes of cat cloning; Factors influencing the color patterning of cloned kitten.
- UK bans human cloning.
Greaves, Sarah // Nature Biotechnology; Jun2001, Vol. 19 Issue 6, p501
Reports on the introduction of a legislation by the Great Britain government that would ban human productive cloning. Permission for the cell nuclear replacement techniques for research purposes by the government; Need for a cloning legislation that distinguishes between therapeutic cloning and...
- Turning back the clock.
Greaves, Sarah // Nature Biotechnology; May2002, Vol. 20 Issue 5, p411
Discusses the U.S Senate's decision on legislation that would outlaw all forms of human cloning. Criminal offense of human nuclear transplantation; Viability of adult stem cells as alternative to cloned embryonic stem cells; Cytoplasm of an egg; Identification of proteins involved in chromatin...
- The Ethical Debate Surrounding Embryo Splitting.
Neuman, Maika // Einstein Quarterly: Journal of Biology & Medicine; 1999, Vol. 16 Issue 2, p84
Discusses the use of the technology of embryo splitting in reducing health risks involved in the treatment of in vitro fertilization. Definition of cloning; Comparison of nuclear transplantation and embryo splitting; Benefits of embryo splitting; Debate on the advantages and disadvantages of...
- Advent of synthetic life.
Rusk, Nicole // Nature Methods; Jul2010, Vol. 7 Issue 7, p487
The article offers information on functional synthetic genome. In 2008 researchers showed cloning of Mycoplasma genitalium genome but could not prove that the genome was functional as they could not transplant it to another bacterium. In 2009 a genome was cloned when genome of M. mycoides was...
- Introducing The Sister-Moms.
Rusk, Nicole // Glamour; 2/ 1/2013, Vol. 111 Issue 2, p123
The article lists women who have used eggs of their sisters to have baby including Jen Kimble, Kelly Cory and Anna Chang-Yen.
- Epigenetic stability of repressed states involving the histone variant macroH2A revealed by nuclear transfer to Xenopus oocytes.
Pasque, Vincent; Halley-Stott, Richard P.; Gillich, Astrid; Garrett, Nigel; Gurdon, J. B. // Nucleus (1949-1034); 2011, Vol. 2 Issue 6, p533
How various epigenetic mechanisms restrict chromatin plasticity to determine the stability of repressed genes is poorly understood. Nuclear transfer to Xenopus oocytes induces the transcriptional reactivation of previously silenced genes. Recent work suggests that it can be used to analyze the...
- Geneticism and germ line: Between courage and caution.
Knoppers, Bartha Maria // Politics & the Life Sciences; Mar98, Vol. 17 Issue 1, p22
Focuses on issues pertaining to geneticism and germ line, with emphasis on egg cell nuclear transfer. Reference to an article written by Andrea Bonnicksen on issues pertaining to egg cell nuclear transfer; Measures taken to avoid the naming of specific techniques; Implications of naming techniques.