Citations with the tag: AXONS
Results 1 - 50
- Axonal Surface Molecules Act in Combination with Sema- phorin 3A during the Establishment of Corticothalamic Projections.
Puschel, Andreas W.; Bolz, Jurgen // Cerebral Cortex; Sep2001, Vol. 11 Issue 9
Presents an erratum on Axonal Surface Molecules Act in Combination with Semaphorin 3A during the Establishment of Corticothalamic Projection, volume 11, number 3, pages 278-285.
- INOSINE IMPROVES FUNCTION IN ANIMALS AFTER STROKE.
Puschel, Andreas W.; Bolz, Jurgen // Biotech Business; Aug2002, Vol. 15 Issue 8, p1
Presents the results of a study that examined the capability of inosine to induce axon growth within the brain and spinal cord.
- Axonal varicosity distributions along parallel fibers: a new angle on a cerebellar circuit.
Shepherd, Gordon M.G.; Raastad, Morten // Cerebellum; Jun2003, Vol. 2 Issue 2, p110
Presynaptic terminals occur along unmyelinated axons in specialized compartments called axonal varicosities or synaptic boutons. Since the first descriptions of varicose axons by Cajal and others, the spatial organization of varicosities along axons has attracted the attention of...
- Referred itch (Mitempfindungen).
Evans, Philip R. // British Medical Journal; 10/9/1976, Vol. 2 Issue 6040, p839
Examines the referred itch or mitempfindungen phenomenon. Method used to assess reaction to scratching; Positions of the stimuli; Context of the branched-axon theory.
- Erratum: Heterogeneity in synaptic transmission along a Drosophila larval motor axon.
Guerrero, Giovanna; Rieff, Dierk F.; Agarwal, Gautam; Ball, Robin W.; Borst, Alexander; Goodman, Corey S.; Isacoff, Ehud Y. // Nature Neuroscience; Oct2005, Vol. 8 Issue 10, p1411
Presents a correction to the article "Heterogeneity in Synaptic Transmission Along a Drosophila Larval Motor Axon" in the October 1, 2005 issue of "Nature Neuroscience."
- Robo is Abl to block N-Cadherin function.
Emerson, Mark M.; Van Vactor, David // Nature Cell Biology; Oct2002, Vol. 4 Issue 10, pE227
The molecular pathways involved in wiring the brain have just begun to be elucidated. Work in this issue of Nature Cell Biology has uncovered inhibitory interactions between two such pathways: Roundabout (Robo) and N-Cadherin. This discovery provides a potential mechanistic understanding of how...
- Preassembly and transport of nerve terminals: a new concept of axonal transport.
Roos, Jack; Kelly, Regis B. // Nature Neuroscience; May2000, Vol. 3 Issue 5, p415
Describes a synapse formation wherein presynaptic elements are assembled into prototerminals before being transported down axons by fast, salttory movement. Effect of axon's contact with dendrites on the synapse formation.
- Mapping Drosophila olfactory axons.
Narasimhan, Kalyani // Nature Neuroscience; Aug2000, Vol. 3 Issue 8, p752
Discusses the mapping of the primary olfactory axons of Drosophila. Convergence between neurons and glomerulus.
- Erratum: MuSK controls where motor axons grow and form synapses.
Kim, Natalie; Burden, Steven J // Nature Neuroscience; Feb2008, Vol. 11 Issue 2, p238
A correction to the article "MuSK Controls Where Motor Axons Grow and Form Synapses" is presented.
- Phase locking and noise in the lighthouse model of a neural net with delay.
Haken, Hermann // AIP Conference Proceedings; 2000, Vol. 502 Issue 1, p69
This paper studies the features of a net of pulse-coupled model neurons, taking into account the dynamics of dendrites and axons. The axonal pulses are modeled by d-functions. In the case of small damping of dendritic currents, the model can be treated exactly and explicitly. We exemplify our...
- Creating a Window into the Developing Brain: Observing Axon Growth in Live Mice.
Portera-Cailliau, C.; Weimer, R. M.; De Paola, V.; Caroni, P.; Svoboda, K. // PLoS Biology; Aug2005, Vol. 3 Issue 8, p1340
Presents an abstract of the article "Diverse Modes of Axon Elaboration in the Developing Neocortex," by C. Portera-Cailliau, R. M. Weimer and V. De Paola, published in the August 15, 2005 issue of "PLoS Biology."
- Dynamic regulation of axon guidance.
Yu, Timothy W.; Bargmann, Cornelia I. // Nature Neuroscience; Nov2001 Supplement, Vol. 4 Issue 11, p1169
To reach their proper targets, axons rely upon the actions of highly conserved families of attractive and repulsive guidance molecules, including the netrins, Slits, semaphorins and ephrins. These guidance systems are used to generate an astonishingly varied set of neuronal circuits. Here we...
Yu, Timothy W.; Bargmann, Cornelia I. // Encyclopedic Reference of Molecular Pharmacology; 2004, p158
A definition of the term "axon" is presented.
- Fast axonal transport is required for growth cone advance.
Martenson, Chris; Stone, Kimberly // Nature; 11/4/1993, Vol. 366 Issue 6450, p66
Suggests that axon elongation requires fast axonal transport but growth cone motility does not. Blocking vesicular transport within an axon by laser tweezers; Occurrence of cytoskeletal breaks and simple explanation for these findings; Summary of growth cone behavior.
- Netrins find their receptor.
Drescher, Uwe // Nature; 12/5/1996, Vol. 384 Issue 6608, p416
Provides background and analysis of a group of studies which have cloned the receptor for netrins. The cloning from Caenorhabditis elegans, rat, and Drosophila; The intense interest in axon guidance; The degree of conservation of this system in organisms; The reports as found in a 1996 issue of...
- Just a chemical attraction.
Smith, Stephen J. // Nature; 3/10/1994, Vol. 368 Issue 6467, p101
Discusses a report on the chemoattractive properties of neurotransmitters. Role of cell surface and extracellular matrix molecules in axon guidance; Dependence of neural development on activity.
Smith, Stephen J. // Taber's Cyclopedic Medical Dictionary (2009); 2009, Issue 21, p763
A definition of the term "end-bulb," which refers to the enlarged tip of the end of an axon, is presented.
Smith, Stephen J. // Taber's Cyclopedic Medical Dictionary (2009); 2009, Issue 21, p1479
An encyclopedia entry for the medical acronym "MLF," which stands for medial longitudinal fasciculus, is presented.
Smith, Stephen J. // Taber's Cyclopedic Medical Dictionary (2009); 2009, Issue 21, p2080
A definition of the term "schizaxon," an axon which divides in two equal branches, is presented.
- teledendrite, teledendron.
Smith, Stephen J. // Taber's Cyclopedic Medical Dictionary (2009); 2009, Issue 21, p2283
A definition of the terms "teledendrite" and "teledendron," which refer to one of the terminal processes of an axon, is presented.
- A no-Wnt situation: SFRPs as axon guidance molecules.
Drescher, Uwe // Nature Neuroscience; Oct2005, Vol. 8 Issue 10, p1281
Evaluate the role of secreted frizzled related protein-1 (SFRP1) as a repulsive guidance molecule for retinal axons on their way to the tectum, signaling through the receptor Fz2. Characteristic for an axon guidance molecule; Functions of SFRP1 as axon guidance molecule; Inhibition of protein...
- Development: Bricks for different houses.
Wiedemann, Claudia // Nature Reviews Neuroscience; Oct2007, Vol. 8 Issue 10, p737
The article reports on several of the factors affecting axonal and dendritic development. The author cites the supply of membrane components to growth cones by the secretory pathway as one of the requirements for the outgrowth of dendrites and axons. However, there is no credible explanation to...
- The Drosophila Netrin receptor Frazzled guides axons by controlling Netrin distribution.
Hiramoto, Masaki; Hiromi, Yasushi; Giniger, Edward; Hotta, Yoshiki // Nature; 8/24/2000, Vol. 406 Issue 6798, p886
Presents a study which shows that the receptor Frazzled can capture Netrin, a protein which can act as a chemotropic axon guidance cue, and present it for recognition by other receptors in Drosophila. Localization of Frazzled; How it can affect Netrin gene expression; Distribution of Netrin in...
- Diffuse axonal injury: detection of changes in anisotropy of water diffusion by diffusion-weighted imaging.
Chan, J.H.M.; Tsui, E.Y.K.; Peh, W.C.G.; Fong, D.; Fok, K.F.; Leung, K.M.; Yuen, M.K.; Fung, K.K.L. // Neuroradiology; Jan2003, Vol. 45 Issue 1, p34
Myelinated axons of white matter demonstrate prominent directional differences in water diffusion. We performed diffusion- weighted imaging on ten patients with head injury to explore the feasibility of using water diffusion anisotropy for quantitating diffuse axonal injury. We showed...
Chan, J.H.M.; Tsui, E.Y.K.; Peh, W.C.G.; Fong, D.; Fok, K.F.; Leung, K.M.; Yuen, M.K.; Fung, K.K.L. // Hutchinson Dictionary of Scientific Biography; 2005, p1
In a nerve fiber, the cytoplasm of an axon, containing the
- Axonal Surface Molecules Act in Combination with Semaphorin ACA during the Establishment of Corticothalamic Projections.
Bagnard, Dominique; Chounlamountri, Naura; Puschel, Andreas W.; Bolz, Jurgen // Cerebral Cortex; Mar2001, Vol. 11 Issue 3, p278
Presents a study on the effect of the addition of semaphorin 3A on the behavior of neocortical and thalamic axons during the establishment of neuronal connections. Overview of the connections between projection neurons in the cerebral cortex and relay neurons in the thalamus during embryonic...
- Axons and multiple sclerosis.
Alix, J. J. P. // Multiple Sclerosis (13524585); Feb2009, Vol. 15 Issue 2, p278
A letter to the editor is presented in response to the article about pathophysiology of axon pathology in multiple sclerosis by A. Wilkins and N. Scolding.
- Identification of Semaphorin3B as a Direct Target of p53.
Ochi, Kensuki; Mori, Toshiki; Toyama, Yoshiaki; Nakamura, Yusuke; Arakawa, Hirofumi // Neoplasia; Jan/Feb2002, Vol. 4 Issue 1, p82
Presents a study which identified Semaphorin3B, a gene whose product is involved in axon guidance and axonal repulsion, as a Direct Target of p53. Method used to identify additional p53 targets; Functions of semaphorins in axon guidance and axonal repulsion; Role of p53 in neuronal apoptosis.
- Come together.
Walterscheid, Ellen // Sciences; Jul/Aug99, Vol. 39 Issue 4, p8
Focuses on the efforts of scientists to develop techniques of repairing severed axons and nerves using biological substances. Promise of polyethylene glycol; Speed in which the substance repair axons; Testing the method on invertebrates and mammals. INSET: Q-bits..
- Axon extruder forms two blown film tubes.
Walterscheid, Ellen // Plastics News; 3/18/2002, Vol. 14 Issue 3, p24
Introduces the blown film extruder from machinery maker Axon AB in Sweden.
- Scene segmentation by spike synchronization in reciprocally connected visual areas. II. Global assemblies and synchronization on larger space and time scales.
Knoblauch, Andreas; Palm, G�nther // Biological Cybernetics; 2002, Vol. 87 Issue 3, p168
We present further simulation results of the model of two reciprocally connected visual areas proposed in the first paper [Knoblauch and Palm (2002) Biol Cybern 87:151�167]. One area corresponds to the orientation�selective subsystem of the primary visual cortex, the other is modeled as an...
- Postnatal development of tyrosine hydroxylase- and dopamine transporter-immunoreactive axons in monkey rostral entorhinal cortex.
Erickson, SL; Akil, M; Levey, AI; Lewis, DA // Cerebral Cortex; Jul98, Vol. 8 Issue 5, p415
Dopamine afferents from the mesencephalon appear to play a critical role in the normal development and cognitive functions of multiple areas of the primate cerebral cortex. In some regions, such as the prefrontal and motor cortices, dopamine innervation changes substantially during postnatal...
- Life on the road.
Flanagan, John G. // Nature; 10/21/99, Vol. 401 Issue 6755, p747
Discusses how axons, to form the connections of the nervous system, find their targets. Guidance molecules sent out by intermediate targets that act as signposts; Prevention of programmed cell death; Experiment done by Hai Wang and Marc Tessier-Lavigne of the University of California in San...
- The protocadherin Flamingo is required for axon target selection in the Drosophila visual system.
Lee, Roger C; Clandinin, Thomas R; Lee, Chi-Hon; Chen, Pei-Ling; Meinertzhagen, Ian A; Zipursky, S Lawrence // Nature Neuroscience; Jun2003, Vol. 6 Issue 6, p557
Photoreceptor neurons (R cells) in the Drosophila visual system elaborate a precise map of visual space in the brain. The eye contains some 750 identical modules called ommatidia, each containing eight photoreceptor cells (R1-R8). Cells R1-R6 synapse in the lamina; R7 and R8 extend through the...
- Activation of the repulsive receptor Roundabout inhibits N-cadherin-mediated cell adhesion.
Rhee, Jinseol; Mahfooz, Najmus S.; Arregui, Carlos; Lilien, Jack; Balsamo, Janne; VanBerkum, Mark F.A. // Nature Cell Biology; Oct2002, Vol. 4 Issue 10, p798
The formation of axon trajectories requires integration of local adhesive interactions with directional information from attractive and repulsive cues. Here, we show that these two types of information are functionally integrated; activation of the transmembrane receptor Roundabout (Robo) by its...
- Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity.
Nishimura, Takashi; Kato, Katsuhiro; Yamaguchi, Tomoya; Fukata, Yuko; Ohno, Shigeo; Kaibuchi, Kozo // Nature Cell Biology; Apr2004, Vol. 6 Issue 4, p328
Neurons polarize to form elaborate multiple dendrites and one long axon. The establishment and maintenance of axon/dendrite polarity are fundamentally important for neurons. Recent studies have demonstrated that the polarity complex PAR-3-PAR-6-atypical protein kinase C (aPKC) is involved in...
- Presynaptic modulation of CA3 network activity.
Staley, Kevin J.; Longacher, Mark; Bains, Jaideep S.; Yee, Audrey // Nature Neuroscience; Jul98, Vol. 1 Issue 3, p201
The simultaneous discharge of hippocampal CA3 pyramidal cells is a widely studied in vitro model of physiological and pathological network synchronization. This network is rapidly activated because of extensive positive feedback mediated by recurrent axon collaterals. Here we show that...
- Axon guidance mechanisms: semaphorins as simultaneous repellents and anti-repellents.
Chen, Hang; He, Zhigang; Tessier-Lavigne, Marc // Nature Neuroscience; Oct98, Vol. 1 Issue 6, p436
Semaphorins A and E are known to potently repel sympathetic axons. New work indicates that they can also antagonize the repellent action of semaphorin D at sensory axons.
- Neuronal growth cone collapse triggers lateral extensions along trailing axons.
Davenport, Roger W.; Thies, Edda; Cohen, Matthew L. // Nature Neuroscience; Mar1999, Vol. 2 Issue 3, p254
Axonal outgrowth is generally thought to be controlled by direct interaction of the lead growth cone with guidance cues, and, in trailing axons, by fasciculation with pioneer fibers. Responses of axons and growth cones were examined as cultured retinal ganglion cell (RGC) axons encountered...
- CPG15 and the dynamics of retinotectal synapses.
Udin, Susan // Nature Neuroscience; Oct2000, Vol. 3 Issue 10, p971
Reports that the overexpression of the activity-dependent protein CPG15 in Xenopus tectal cells promotes the growth of tectal dendrites and retinal axons. Coordination of development; Proliferation and differentiation of retinal and tectal cells; Degrees of arborization.
- Postsynaptic filopodia in muscle cells interact with innervating motoneuron axons.
Ritzenthaler, Sarah; Suzuki, Emiko; Chiba, Akira // Nature Neuroscience; Oct2000, Vol. 3 Issue 10, p1012
Precise synaptogenesis is crucial to brain development, and depends on the ability of specific partner cells to locate and communicate with one another. Dynamic properties of axonal filopodia during synaptic targeting are well documented, but the cytomorphological dynamics of postsynaptic cells...
- Postsynaptic CPG15 promotes synaptic maturation and presynaptic axon arbor elaboration in vivo.
Cantallops, Isabel; Haas, Kurt; Cline, Hollis T. // Nature Neuroscience; Oct2000, Vol. 3 Issue 10, p1004
The formation of CNS circuits is characterized by the coordinated development of neuronal structure and synaptic function. The activity-regulated candidate plasticity gene 15 (cpg15) encodes a glycosylphosphatidylinositol (GPI)-Iinked protein whose in vivo expression increases the dendritic...
- Visualizing synapse formation in arborizing optic axons in vivo: dynamics and modulation by BDNF.
Alsina, Berta; Vu, Thuy; Cohen-Cory, Susana // Nature Neuroscience; Nov2001, Vol. 4 Issue 11, p1093
Dynamic developmental changes in axon arbor morphology may directly reflect the formation, stabilization and elimination of synapses. We used dual-color imaging to study, in the live, developing animal, the relationship between axon arborization and synapse formation at the single cell level,...
- Does bouton morphology optimize axon length?
Anderson, John C.; Martin, Kevan A. C. // Nature Neuroscience; Dec2001, Vol. 4 Issue 12, p1166
The total length of cortical axons could be reduced if the parent axons maintained straight trajectories and simply connected to dendritic shafts via spine-like terminaux boutons and to dendritic spines via bead-like en passant boutons. Cortical axons from cat area 17 were reconstructed from...
- Pre-existing pathways promote precise projection patterns.
Nguyen, Quyen T.; Sanes, Joshua R.; Lichtman, Jeff W. // Nature Neuroscience; Sep2002, Vol. 5 Issue 9, p861
A large body of evidence shows that molecular cues promote specific synapse formation by guiding axons and by mediating their association with targets, but much less is known about the contribution of physical cues (such as mechanical constraints) to these processes. Here we used the peripheral...
- A p75NTR and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein.
Wong, Scott T.; Henley, John R.; Kanning, Kevin C.; Huang, Kuo-hua; Bothwell, Mark; Poo, Mu-ming // Nature Neuroscience; Dec2002, Vol. 5 Issue 12, p1302
Myelin-associated glycoprotein (MAG), an inhibitor of axon regeneration, binds with high affinity to the Nogo-66 receptor (NgR). Here we report that the p75 neurotrophin receptor (p75[sup NTR]) is a coreceptor of NgR for MAG signaling. In cultured human embryonic kidney (HEK) cells expressing...
- Dendrites go up, axons go down.
Strittmatter, Stephen M. // Nature; 4/6/2000, Vol. 404 Issue 6778, p557
Reports on the findings of a study describing how a guidance factor designated as semaphorin 3A (Sema3A) acts as a chemoattractant for dendrites growing from certain neurons. Function of Sema3A in the development of cerebral cortex; Linking of Sema3A to the determination of direction of axon...
- Some Nerve!
Feldman, Ruth Tenzer // Odyssey; Mar2001, Vol. 10 Issue 3, p49
Discusses how the squid's giant axon helps scientists better understand the human brain.
Feldman, Ruth Tenzer // Packaging Digest; Oct2001, Vol. 38 Issue 10, p92
Reports the release of a product brochure from Axon Corp. Various applications of the company products; Provision of information on technology models of the firm; Discussion on continuous machine motion in the brochure.
- The costs of axonal communication.
Levy, William; Crotty, Patrick // BMC Neuroscience; 2007 Supplement 2, Vol. 8, pP163
An abstract of the paper "The Costs of Axonal Communication," by William Levy and Patrick Crotty, is presented.