Of mice and men: elucidating the role of SH2-containing inositol 5-phosphatase (SHIP) in human disease

Rauh, Michael J.; Krystal, Gerald
June 2002
Clinical & Investigative Medicine;Jun2002, Vol. 25 Issue 3, p68
Academic Journal
Focuses on the role of SH2-domain-containing inositol 5-phosphatase (SHIP) as a negative regulator of hemopoietic cell proliferation, survival and end cell activation. Description of how the protein carry out the negative function; Outcome of studies of SHIP in mice; Implications for human disease treatment.


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