HCV infection among cocaine users in the state of Pará, Brazilian Amazon

Oliveira-Filho, Aldemir; Sawada, Leila; Pinto, Laine; Locks, Daiane; Bahia, Santana; Brasil-Costa, I.; Lemos, José
July 2013
Archives of Virology;Jul2013, Vol. 158 Issue 7, p1555
Academic Journal
In this study, the prevalence, genotype frequency, and risk factors for HCV infection in 384 cocaine users were determined. One hundred twenty-four (32.3 %) cocaine users had anti-HCV antibodies and 120 (31.3 %) had HCV-RNA. Genotyping results indicated the predominance of genotypes 1 (73.3 %) and 3 (26.7 %). Multivariate analysis showed an association of HCV infection with tattoos, shared use of paraphernalia, daily cocaine use, and a long history of cocaine use. The epidemiological aspects of HCV infection among cocaine users presented here should serve as an incentive for the establishment of a program of hepatitis C prevention and control by the local public-health authorities in the Amazon.


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