TITLE

The simultaneous occurrence of human norovirus and hepatitis E virus in a Norway rat ( Rattus norvegicus)

AUTHOR(S)
Wolf, Sandro; Reetz, Jochen; Johne, Reimar; Heiberg, Ann-Charlotte; Petri, Samuel; Kanig, Hanna; Ulrich, Rainer
PUB. DATE
July 2013
SOURCE
Archives of Virology;Jul2013, Vol. 158 Issue 7, p1575
SOURCE TYPE
Academic Journal
DOC. TYPE
Report
ABSTRACT
Wild rats can be reservoirs and vectors for several human pathogens. An initial RT-PCR screening of the intestinal contents of Norway rats trapped in the sewer system of Copenhagen, Denmark, for caliciviruses revealed the presence of a human norovirus in one of 11 rodents. Subsequent phylogenetic analysis of the ~4.0-kb 3′-terminus of the norovirus genome resulted in the identification of a recombinant GI.b/GI.6 strain. The simultaneous detection of hepatitis E virus-like particles in the feces of this rat by transmission electron microscopy was confirmed by RT-PCR and sequence determination, resulting in the identification of a novel rat hepatitis E virus.
ACCESSION #
88428254

 

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