Prognostic Factors in 61 Cases of Staphylococcus aureus Prosthetic Valve Infective Endocarditis from the International Collaboration on Endocarditis Merged Database

Chirouze, C.; Cabell, C. H.; Fowler Jr., V. G.; Khayat, N.; Olaison, L.; Miro, J. M.; Habib, G.; Abrutyn, E.; Eykyn, S.; Corey, G. R.; Selton-Suty, C.; Hoen, B.
May 2004
Clinical Infectious Diseases;5/1/2004, Vol. 38 Issue 9, p1323
Academic Journal
Staphylococcus aureus prosthetic valve infective endocarditis (SA-PVIE) is associated with a high mortality rate, but prognostic factors have not been clearly elucidated. The Inter- national Collaboration on Endocarditis merged database (ICE-MD) contained 2212 cases of definite infective endocarditis (as defined using the Duke criteria), 61 of which were SA-PVIE. Overall mortality rate was 47.5%, stroke was associated with an increased risk of death, and early valve replacement was not associated with a significant survival benefit in the whole population; however, patients who developed cardiac complications and underwent early valve replacement had the lowest mortality rate (28.6%).


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