Unintended Smallpox Vaccination of HIV-1--Infected Individuals in the United States Military

Tasker, Sybil A.; Schnepf, Glenn A.; Lim, Matthew; Caraviello, Harold E.; Armstrong, Adam; Bavaro, Mary; Agan, Brian K.; Delmar, Judith; Aronson, Naomi; Wallace, Mark R.; Grabenstein, John D.
May 2004
Clinical Infectious Diseases;5/1/2004, Vol. 38 Issue 9, p1320
Academic Journal
We identified 10 individuals who had undiagnosed human immunodeficiency virus type 1 (HIV-1) infection at the time of smallpox vaccination. Mean CD4 cell count was 483 cells/ mm³ (range, 286-75 1 cells/mm³), and mean log10 plasma HIV-1 RNA load was 4.13 copies/cm³ (range, 2.54-5.16 copies/cm3). All vaccinees (3 primary and 7 repeat) had a normal, robust reaction without complications. Smallpox vaccine was well-tolerated in this small series of HIV-1-infected military personnel.


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