muscular dystrophy

Peters, Michael
June 2004
BMA A-Z Family Medical Encyclopedia;2004, p524
Reference Entry
An encyclopedia entry for the term "muscular dystrophy" is presented. It refers to a group of rare inherited muscle disorders that are characterized by slow, progressive wasting of muscle fibres. Duchenne muscular dystrophy is the most common and severe form of muscular dystrophy. Particular focus is given to Duchene's etiology and incidence. Other kinds of muscular dystrophy are Becker's muscular dystrophy and limb-girdle muscular dystrophy. Also included are information on the diagnosis, treatment options and prognosis.


Related Articles

  • Duchenne and Becker Muscular Dystrophy: Contribution of a Molecular and Immunohistochemical Analysis in Diagnosis in Morocco. Bellayou, Hanane; Hamzi, Khalil; Rafai, Mohamed Abdou; Karkouri, Mehdi; Slassi, Ilham; Azeddoug, Houssine; Nadifi, Sellama // Journal of Biomedicine & Biotechnology;2009 Regular Issue, p1 

    Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X-linked recessive disorders caused by mutations of the DMD gene located at Xp21. In DMD patients, dystrophin is virtually absent; whereas BMD patients have 10% to 40% of the normal amount. Deletions in the dystrophin gene...

  • Becker and Duchenne muscular dystrophy: a two-way information process for therapies. Lochmüller, Hanns; Bushby, Kate // Journal of Neurology, Neurosurgery & Psychiatry;Jan2014, Vol. 85 Issue 1, p5 

    In this article, the authors reflect on a research by researcher J.C. van den Bergen and colleagues related to the treatment of Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy (DMD). They state that antisense oligonucleotide (AON)-mediated exon skipping clinical testing method...

  • Molecular and Clinical Correlations of Deletions Leading to Duchenne and Becker Muscular Dystrophies.  // JAMA: Journal of the American Medical Association;10/6/89, Vol. 262 Issue 13, p1762 

    Discusses the abstract of the article 'Molecular and Clinical Correlations of Deletions Leading to Duchenne and Becker Muscular Dystrophies,' by L.L. Baumbach et al., published in a 1989 issue of the 'Neurology' journal.

  • Manifestations of Duchenne and Becker muscular dystrophy among carriers.  // European Journal of Pediatrics;1999, Vol. 158 Issue 11, pA946 

    Examines the frequency and severity of Duchenne and Becker muscular dystrophy in a series of carriers. Signs of dilated cardiomyopathy and left-ventricle dilation; Comparison between muscle weakness and dilated cardiomyopathy; Reason for determining carriership.

  • Screening for minor changes in the distal part of the human dystrophin gene in Greek DMD/BMD patients. Kekou, Kiriaki; Mavrou, Ariadni; Florentin, Lina; Youroukos, Sotiris; Zafiriou, Dimitrios I; Skouteli, Helen N; Metaxotou, Catherine // European Journal of Human Genetics;Mar1999, Vol. 7 Issue 2, p179 

    The distal part of the human dystrophin gene is characterised by particular features and seems to play an important functional role. Additionally in recent years several data have implicated minor mutations in this gene region in some patients with mental retardation (MR). In order to screen for...

  • Characterization of deletion breakpoints in patients with dystrophinopathy carrying a deletion of exons 45—55 of the Duchenne muscular dystrophy (DMD) gene. Miyazaki, Daigo; Yoshida, Kunihiro; Fukushima, Kazuhiro; Nakamura, Akinori; Suzuki, Kayo; Sato, Toshiyuki; Takeda, Shin'ichi; Ikeda, Shu-ichi // Journal of Human Genetics;Feb2009, Vol. 54 Issue 2, p127 

    Deletion of exons 45–55 (del45–55) in the Duchenne muscular dystrophy gene (DMD) has gained particular interest in the field of molecular therapy, because it causes a milder phenotype than DMD, and therefore, may represent a good candidate for the goal of a multiple exon-skipping...

  • Diagnosis and new treatments in muscular dystrophies. A Y Manzur // Postgraduate Medical Journal;Nov2009, Vol. 85 Issue 1009, p622 

    Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD) and limb girdle muscular dystrophies (LGMD) represent a significant proportion of paediatric and adult neuromuscular neurology practice. The proactive symptom-based multidisciplinary team (MDT) management and access to...

  • Poster 452 Risk Factors for Fractures Among Males with Duchenne or Becker Muscular Dystrophy. Apkon, Susan; Ciafaloni, Emma; Cunniff, Christopher; Holtzer, Caleb; James, Kathy; Lu, Zhenqiang; Matthews, Katherine; Miller, Lisa; Pandya, Shree // PM & R: Journal of Injury, Function & Rehabilitation;Oct2012 Supplement 10S, Vol. 4, pS183 

    No abstract available.

  • Duchenne and Becker muscular dystrophies. Driscoll, Deborah A. // Contemporary OB/GYN;Oct2001, Vol. 46 Issue 10, p97 

    Focuses on Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). Description of the gene responsible for DMD and BMD; Tests that are recommended for the diagnosis of DMD and BMD; Information on prenatal testing for the disease.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics