Leucine Zipper

January 2001
Encyclopedic Reference of Cancer;2001, p497
Reference Entry
A definition of the term "leucine zipper" is presented. This term refers to an ampiphatic α-helical motif in which leucine residues are present every seven amino acids. This forms a hydrophobic stretch on the α-helix surface. Hydrophobic interactions mediate the dimerization of two leucine-zipper containing proteins.


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