TITLE

Leucin Zipper

PUB. DATE
January 2004
SOURCE
Encyclopedic Reference of Molecular Pharmacology;2004, p550
SOURCE TYPE
Book
DOC. TYPE
Reference Entry
ABSTRACT
A definition of the term "leucine zipper" is presented. It refers to a structural motif present in a large class of transcription factors. These dimeric proteins contain two extended alpha helices that grip the DNA molecule much like a pair of scissors at adjacent major grooves. Some DNA-binding proteins with this general motif contain other hydrophobic amino acids in these positions.
ACCESSION #
22802808

 

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