Tay-Sachs disease

January 2005
Taber's Cyclopedic Medical Dictionary;2005, p2147
Reference Entry
A definition of the term "Tay-Sachs disease" is presented. It refers to the most severe of the lipid storage diseases. This disease is marked by neurological deterioration in the first year of life. A genetic abnormality on chromosome 15 causes the disease. The metabolic abnormality results in the deficient manufacture of lysosomal beta-hexosamindase A.


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