TITLE

somatomedin

PUB. DATE
January 2005
SOURCE
Taber's Cyclopedic Medical Dictionary;2005, p2026
SOURCE TYPE
Book
DOC. TYPE
Reference Entry
ABSTRACT
A definition of the term "somatomedin," is presented. It refers to a group of insulin-like growth factors that require growth hormone in order to exert their function of stimulating growth. These proteins are produced in the liver and other tissues.
ACCESSION #
21245977

 

Related Articles

  • Insulin-like Binding Proteins.  // Encyclopedic Reference of Cancer;2001, p455 

    A definition of the term "insulin-like binding proteins" is presented. These are large molecular proteins seen in local tissue environments and in circulation. Insulin-like binding proteins tie up insulin-like growth factors (IGF). These proteins tie up IGF to regulate their half-life and functions.

  • Insulin-Like Growth Factor I: Implications in Aging. Arvat, E.; Broglio, F.; Ghigo, E. // Drugs & Aging;2000, Vol. 16 Issue 1, p29 

    According to the somatomedin model, growth hormone (GH)-dependent hepatic synthesis is responsible for maintaining circulating insulin-like growth factor (IGF)-I levels. On the other hand, the local autocrine/paracrine IGF-I expression in peripheral tissue is generally GH-independent and...

  • Insulin-Like Growth Factors Expression.  // Current Medical Literature: GH & Growth Factors;2003, Vol. 18 Issue 1, p24 

    Presents citations and clinicians' notes on insulin-like growth factors (IGF) expression. Effect of glucocorticoid treatment on IGF-I and its binding proteins in children with nephrotic syndrome; Association of low serum IGF-I with increased risk of ischemic heart disease; Dietary correlates of...

  • Failure of IGF-A and IGFBP-3 to diagnose growth-hormone insufficiency.  // European Journal of Pediatrics;2000, Vol. 159 Issue 1/2, pA128 

    Presents information on a study that tested the reliability of insulin-like growth factor I (IGF-1) testing alone and in combination with the determination of IGF binding protein (IGFBP). Measurement of the concentrations of IGF-1 and IGFBP-3 in serum samples; Assessment of various cut-off...

  • Targeting the IGF-1 Pathways. Schor, Jacob // Townsend Letter;Aug/Sep2015, Issue 385/386, p56 

    The article explains the functions of the insulin-like growth factors (IGF)-1 to optimize the dietary and lifestyle strategies in treating cancer. Topics discussed include IGF-1 and IGF2 as proteins produced by the liver in response to growth hormone from the pituitary gland in the brain, the...

  • The IRS2 Gly1057Asp Variant Is Associated With Human Longevity. Barbieri, Michelangela; Rizzo, Maria Rosaria; Papa, Michela; Boccardi, Virginia; Esposito, Antonietta; White, Morris F.; Paolisso, Giuseppe // Journals of Gerontology Series A: Biological Sciences & Medical ;Mar2010, Vol. 65A Issue 3, p282 

    Background: Reduced insulin and insulin-like growth factor-1 (IGF-1) signaling extends the life span of invertebrate and mammals. Recently, reduced insulin receptor substrate-2 (IRS2) signaling was found associated with increased longevity in mice. The aim of our study was to evaluate whether a...

  • IGF.  // Current Medical Literature: Growth, Growth Hormone, & Metabolism;2009, Vol. 2 Issue 3, p82 

    The article cites two researches on insulin-like growth factors (IGF). The first study links IGF and their binding proteins to subsequent risk of prostate cancer, while the other shows evidence for relationships between IGF and neoplasia. Data collected from the first study showed that the risk...

  • Insulin-Like Growth Factors | Actions.  // Current Medical Literature: GH & Growth Factors;2003, Vol. 18 Issue 3, p76 

    Discusses abstracts on insulin-like growth factors and their mechanism of action. "Serum IGF-I and IGFBP-3 in healthy pregnancies and patients with preeclampsia," by K. Altinkaynak et al; "Growth velocity during the first postnatal week of life is linked to a spurt of IGF-I effect," by A....

  • Effects of Leptin on Prolactin and IGF-I Secretion of Cultured Rat Endometrial Stromal Cells.  // Fertility Weekly;7/30/2007, p6 

    The article reports on the result of a clinical study conducted by researchers in Sri Lanka which shows the effects of leptin on prolactin and insulin-like growth factor (IGF-I) secretion of cultured rat endometrial stromal cells. Researchers state that leptin enhances prolactin (PRL) secretion...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics