January 2005
Taber's Cyclopedic Medical Dictionary;2005, p1733
Reference Entry
A definition of the term "porphobilinogen" is presented. It is an intermediate product in heme synthesis which sometimes found in the urine of patients with acute porphyria. The urine may appear normal when fresh but will change to a burgundy wine color or even to black when heated with dilute hydrochloric acid.


Related Articles

  • porphyrinuria.  // Taber's Cyclopedic Medical Dictionary;2005, p1734 

    A definition of the term "porphyrinuria" is presented. It refers to the excretion of an increased amount of porphyrin in the urine.

  • porphyria.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p1851 

    A definition of the term "porphyria," which refers to a group of disorders that result from a disturbance in any of the sequential steps involved in the synthesis of heme, causing increased formation and excretion of porphyrin or its precursors, is presented.

  • Demystification of Chester Porphyria: A Nonsense Mutation in the Porphobilinogen Deaminase Gene. Poblete-GutiĆ©rrez, P.; Wiederholt, T.; Martinez-Mir, A.; Merk, H. F.; Connor, J. M.; Christiano, A. M.; Frank, J. // Physiological Research;2006 Supplement, Vol. 55, pS137 

    The porphyrias arise from predominantly inherited catalytic deficiencies of specific enzymes in heme biosynthesis. All genes encoding these enzymes have been cloned and several mutations underlying the different types of porphyrias have been reported. Traditionally, the diagnosis of porphyria is...

  • De Novo Mutation Found in the Porphobilinogen Deaminase Gene in Slovak Acute Intermittent Porphyria Patient: Molecular Biochemical Study. Ulbrichova, D.; Flachsova, E.; Hrdinka, M.; Saligova, J.; Bazar, J.; Raman, C. S.; Martasek, Pavel // Physiological Research;2006 Supplement, Vol. 55, pS145 

    The porphyrias are group of mostly inherited disorders in which a specific spectrum of accumulated and excreted porphyrins and heme precursors are associated with characteristic clinical features. There are eight enzymes involved in the heme synthesis and defects in seven of them cause...

  • 19-YEAR-OLD FEMALE WITH ABDOMINAL PAIN. Buraga, Ioan; Dobrescu, Adrian-Florin // Romanian Journal of Neurology;2013, Vol. 12 Issue 1, p30 

    Porphyria is a group of at least 8 diseases that differ greatly between them. Common feature of these diseases is the accumulation in the body of porphyrins or porphyrin precursors, due to defects of specific enzymes in the biosynthesis of heme. Many symptoms of porphyria are nonspecific and...

  • protoporphyrinuria.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p1917 

    A definition of the term "protoporphyrinuria," which refers to protoporphyrin in the urine, is presented.

  • uroporphyria.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p2418 

    A definition of the medical term "uroporphyria" is presented, which refers to the excessive amount of uroporphyrin in the urine.

  • uroporphyrinogen.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p2418 

    A definition of the medical term "uroporphyrinogen" is presented, which refers to one of the precursors of uroporphyrins.

  • Protoporphyrin IX.  // Encyclopedic Reference of Cancer;2001, p733 

    A definition of the term "protoporphyrin IX" is presented. It refers to a naturally occurring fluorophore. Protoporphyrin IX is the immediate precursor of heme in the heme-synthetic pathway and may be used to detect neoplasia by fluorescence. Its concentration in neoplastic tissue may be...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics