TITLE

orphenadrine hydrochloride

PUB. DATE
January 2002
SOURCE
Royal Society of Medicine: Medicines;2002, p414
SOURCE TYPE
Book
DOC. TYPE
Reference Entry
ABSTRACT
The article presents information on orphenadrine hydrochloride which is an anticholinergic (antimuscarinic) drug which is used in the treatment of some types of parkinsonism. It increases mobility and decreases rigidity and tremor, but has only a limited effect on bradykinesia, and also the tendency to produce an excess of saliva is reduced. It is thought to work by correcting the over-effectiveness of the neurotransmitter (cholinergic excess), which is caused by the deficiency of dopamine that occurs in parkinsonism. It also has the capacity to treat these conditions, in some cases, where they are produced by drugs. Administration is oral.
ACCESSION #
18960848

 

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