Repeat celiac screening in type 1 diabetes

Mack, David
December 2003
American Journal of Gastroenterology;Dec2003, Vol. 98 Issue 12, p2592
Academic Journal
Reports on the longitudinal serological screening of endomysial antibodies (EMA) in children with type 1 diabetes mellitus. Immunoglobulin A testing of all children; Intestinal biopsy for patients with a positive EMA to prove the presence of celiac disease; Consideration of a follow-up screening even if initial celiac disease blood screening might be negative in diabetic patients.


Related Articles

  • In vivo targeting of intestinal and extraintestinal transglutaminase 2 by coeliac autoantibodies. Korponay-Szabó, I. R.; Halttunen, I.; Szalai, Z.; Laurila, K.; Király, R.; Kovács, J. B.; Fésüs, L.; Möki, M. // Gut;May2004, Vol. 53 Issue 5, p641 

    Background: IgA class serum autoantibodies against type 2 (tissue) transglutaminase (TG2) bind to both intestinal and extraintestinal normal tissue sections in vitro, eliciting endomysial, reticulin, and jelunal antibody reactions. It is not known whether similar binding also occurs in coeliac...

  • Editorial: Commentary on “Anti-Pituitary Antibodies in Children With Newly Diagnosed Celiac Disease: A Novel Finding Contributing to Linear Growth”. Fasano, Alessio; Counts, Debra // American Journal of Gastroenterology;Mar2010, Vol. 105 Issue 3, p697 

    The pathogenesis of celiac disease (CD)-associated short stature is still unclear. The authors showed that newly diagnosed CD patients have a high prevalence of positive antipituitary antibodies that correlates with height impairment. Given the association of CD with other autoimmune disease,...

  • Low Prevalence of Antigliadin and Anti-Endomysium Antibodies in Subclinical/Silent Celiac Disease. Tunsi, Antonio; Brandimarte, Giovanni; Giorgetti, GianMarco; Gigliobianco, Andrea; Lombardi, Domenico; Gasbarrini, Giovanni // American Journal of Gastroenterology;May2001, Vol. 96 Issue 5, p1507 

    OBJECTIVE: Endomysial antibodies (EMA) are a well-known hallmark of celiac disease, but some recent studies showed that the prevalence of these antibodies in clinical practice is lower than expected. The aim of our study was to determine the prevalence of antigliadin (AGA) and EMA antibodies on...

  • What blood tests help diagnose celiac disease? Reddick, Bonzo K.; Crowell, Karen // Journal of Family Practice;Dec2006, Vol. 55 Issue 12, p1088 

    The article discusses the kind of blood tests which help diagnose celiac disease. The study has revealed that the histological confirmation of infiltrative lesions thru small bowel biopsy was the gold standard for diagnosing celiac disease. It has noted four serum antibody assays which may serve...

  • Nationwide study of childhood celiac disease incidence over a 35-year period in Estonia. Ress, Krista; Luts, Katrin; Rägo, Tiina; Pisarev, Heti; Uibo, Oivi // European Journal of Pediatrics;Dec2012, Vol. 171 Issue 12, p1823 

    The aims of the study were to analyze the trends and characteristics of the incidence and clinical presentation of childhood celiac disease (CD) from 1976 to 2010 in Estonia. The study included all children up to 19 years of age diagnosed with small bowel biopsy proven CD. During a 35-year...

  • Jejunal Biopsy in Celiac Disease. McNicholl, Brian; Egan, Bridget // Clinical Pediatrics;Sep1968, Vol. 7 Issue 9, p544 

    Assesses the usefulness of peroral jejunal biopsies in celiac disease. Definition of celiac disease; Symptoms of celiac disease; Procedures of jejunal biopsy; Gradings in the biopsy specimen findings; Diagnosis and management of celiac disease in childhood.

  • Majority of Children With Type 1 Diabetes Produce and Deposit Anti-Tissue Transglutaminase Antibodies in the Small Intestine. Maglio, Mariantonia; Florian, Fiorella; Vecchiet, Monica; Auricchio, Renata; Paparo, Francesco; Spadaro, Raffaella; Zanzi, Delia; Rapacciuolo, Luciano; Franzese, Adriana; Sblattero, Daniele; Marzari, Roberto; Troncone, Riccardo // Diabetes;Jul2009, Vol. 58 Issue 7, p1578 

    OBJECTIVE--Anti-tissue transglutaminase (TG2) antibodies are the serological marker of celiac disease. Given the close association between celiac disease and type 1 diabetes, we investigated the production and deposition of anti-TG2 antibodies in the jejunal mucosa of type 1 diabetic children....

  • High prevalence of celiac disease among Saudi children with type 1 diabetes: a prospective cross-sectional study. Al-Hussaini, Abdulrahman; Sulaiman, Nimer; Al-Zahrani, Musa; Aleniz, Ahmed; El Haj, Imad // BMC Gastroenterology;2012, Vol. 12 Issue 1, p180 

    Background: There is lack of data on prevalence of celiac disease (CD) in children with type 1 diabetes (T1D) in Arabs in the Middle East. The present investigation aims to study the prevalence rate and clinical characteristics of CD among Saudi children with T1D using a combination of the most...

  • Intestinal Permeability and Antigliadin Antibody Test for Monitoring Adult Patients with Celiac Disease. Eduardo Vilela; Maria de Abreu Ferrari; Henrique de Gama Torres; Fabiana Martins; Eugênio Goulart; Agnaldo Lima; Aloíso da Cunha // Digestive Diseases & Sciences;May2007, Vol. 52 Issue 5, p1304 

    Abstract  Celiac disease causes chronic inflammation of the intestinal mucosa and reduces surface absorption; after the withdrawal of gluten from the diet, there are clinical and histologic improvements. The intestinal permeability test and serologic tests are useful for confirming the...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics