Is There Clear and Convincing Evidence of Cardiovascular Risk with Rosiglitazone?

Kaul, S.; Diamond, G. A.
June 2011
Clinical Pharmacology & Therapeutics;Jun2011, Vol. 89 Issue 6, p773
Academic Journal
In this article, the author focuses on the cardiovascular safety of rosiglitazone, a thiazolidinedione drug designed for glycemic control among type 2 diabetics. The author states that meta-analyses conducted by the U.S. Food and Drug Administration (FDA) shows the association of rosiglitazone with myocardial infarction and increased risk of ischemic events. The author says that physicians may be free to weigh the risks and benefits of rosiglitazone until evidence of harmful effects is clear.


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