Using Apolipoprotein B to Manage Dyslipidemic Patients: rilime for a Change?

Harper, Charles R.; Jacobson, Terry A.
May 2010
Mayo Clinic Proceedings;May2010, Vol. 85 Issue 5, p440
Academic Journal
In this article the authors discuss the management of dyslipidemic patients using Apolipoprotein B (Apo B). The authors stress the establishment of low-density lipoprotein cholesterol (LDL-C) concentration as the independent risk factor for the development of atherosclerosis. The authors mention that Apo B, the key structural component of all atherogenic lipoprotein particles, is a better marker for total atherogenic particle number.


Related Articles

  • New Methodology and Approaches to Intracellular Lipid Transport in Atherosclerosis and Cardiovascular Disease. Roufogalis, Basil D.; Grewal, Thomas // Current Pharmaceutical Biotechnology;Feb2012, Vol. 13 Issue 2, p276 

    No abstract available.

  • Novel Molecules Targeting Dyslipidemia and Atherosclerosis. Tavridou, A.; Manolopoulos, V. G. // Current Medicinal Chemistry;2008, Vol. 15 Issue 8, p792 

    Atherosclerotic cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Dyslipidemia is one of the main risk factors leading to atherosclerosis. Moreover, there is evidence for a role of oxidation in linking lipids and inflammation to development and progression...

  • Cholesterol?Atherosclerosis Is Kaput!  // Health & Stress;2002, Issue 8, p4 

    Focuses on the link between low-density cholesterol (LDL) and atherosclerosis. Effect of dietary fat on blood cholesterol; Coronary heart disease; Effects of statins.

  • Monounsaturated fat increased the effectiveness of cholesterol-lowering diets.  // Australian Journal of Pharmacy;Sep2011, Vol. 92 Issue 1096, p100 

    The article presents a study that determined whether increasing the monounsaturated fat content of a diet proven effective for lowering low-density lipoprotein (LDL) cholesterol. The study was conducted on twenty-four patients with hyperlipidaemia and were given a therapeutic diet very low in...

  • Tumorouos xanthomas in a young male with familial hypercholdesterolaemia. Rajput, R.; Bhansali, A. // Archives of Disease in Childhood;Oct2006, Vol. 91 Issue 10, p827 

    The article reports on the medical case of a 16-year-old boy who presented with massive bilateral tumorous swellings over his buttocks and who was diagnosed later with tumorous xanthomas with familial hypercholesterolemia. Xanthomas are manifestations of disordered lipid metabolism. Tuberous...

  • Atherogenic Dyslipidemia -- A Medical Underwriter's Iceberg. Gleeson, Robert // Journal of Insurance Medicine;2009, Vol. 41 Issue 4, p264 

    Life insurance medical underwriters assess cardiovascular risk by applying versions of cholesterol guidelines that were written in the early 1980s, when people were not obese, triglyceride levels were lower, and the low-density lipoprotein particles carried 95% of the cholesterol ester. Today in...

  • Familial Hypercholesterolemia: Developments in Diagnosis and Treatment. Klose, Gerald; Laufs, Ulrich; März, Winfried; Windler, Eberhard // Deutsches Aerzteblatt International;8/4/2014, Vol. 111 Issue 31/32, p523 

    Background: Familial hypercholesterolemia (FH) is a congenital disorder of lipid metabolism characterized by a marked elevation of the plasma concentration of LDL (low-density lipoprotein) cholesterol beginning in childhood and by the early onset of coronary heart disease. It is among the...

  • Association of Hyperapobetalipoproteinemia with Endogenous Hypertriglyceridemia and Atherosclerosis. Sniderman, Alan D.; Wolfson, Christina; Teng, Babie; Franklin, Frank A.; Bachorik, Paul S.; Kwiterovich Jr., Peter O. // Annals of Internal Medicine;Dec82, Vol. 97 Issue 6, p833 

    Presents a study that examined the correlation of hyperapobetalipoproteinemia with endogenous hypertriglyceridemia and atherosclerosis. Measurement of plasma low-density lipoprotein (LDL) B protein; Analysis of the clinical manifestations of atherosclerotic disease; Assessment of the level of...

  • Atherosclerosis: What Are We Looking For? Giannoglou, George D.; Chatzizisis, Yiannis S. // Angiology;Oct2012, Vol. 63 Issue 5, p397 

    The article discusses atherosclerosis and factors such as low endothelial shear stress (ESS) determining its severity. It highlights the link between decrease in high-density lipoprotein cholesterol (HDL-C) and increase in very low-density lipoprotein (VLDL) cholesterol promoting atherosclerosis...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics