An Evolving Understanding of Genital Herpes Pathogenesis: Is It Time for Our Approach to Therapy to Change As Well?

Hook III, Edward W.
February 2010
Journal of Infectious Diseases;2/15/2010, Vol. 201 Issue 4, p486
Academic Journal
In this article the author comments on the study on the pathogenesis of genital herpes due to herpes simplex virus (HSV) type 2 in women by S. Tata, C. Johnson, and colleagues. He remarks that the data presented in the study need further investigations to be validated but its findings challenge widely held beliefs that HSV infections domiciliates in solitary or in just one side of the body. Also investigated is the clinical approach to prevention of genital herpes transmission.


Related Articles

  • Recurrent Genital Herpes in a Population Attending a Clinic for Sexually Transmitted Diseases. Löwhagen, G. B.; Tunbäck, P.; Andersson, K.; Johannisson, G. // Acta Dermato-Venereologica;Jan/Feb2001, Vol. 81 Issue 1, p35 

    Patients with recurrent genital herpes attending a sexually transmitted disease clinic were studied and transmission of the infection was elucidated by evaluating serostatus in their partners. Of 84 patients attending for recurrent genital herpes, 94% had a herpes simplex virus type 2 (HSV-2)...

  • Estimating the costs and benefits of screening monogamous, heterosexual couples for unrecognised infection with herpes simplex virus type 2. Fisman, D.N.; Hook III, E.W.; Goldie, S.J.; Hook, E W 3rd // Sexually Transmitted Infections;Feb2003, Vol. 79 Issue 1, p45 

    Objectives: Herpes simplex virus type 2 (HSV-2) is the most common cause of ulcerative genital disease in the United States, but infection is commonly unrecognised. Serological screening tests could identify discordantly infected couples and permit targeted interventions to limit...

  • Fact or fiction: you can catch herpes from a toilet seat. Kelly, Alice Lesch // Shape;May2004, Vol. 23 Issue 9, p128 

    Focuses on conditions required by herpes simplex virus for spreading.

  • health handbook.  // Good Medicine (Australian Consolidated Press);Dec2006, p18 

    The article reveals that 12 percent or one in eight Australian adults have been infected with herpes simplex virus.

  • Persistent Genital Herpes Simplex Virus-2 Shedding Years Following the First Clinical Episode. Phipps, Warren; Saracino, Misty; Magaret, Amalia; Selke, Stacy; Remington, Mike; Meei-Li Huang; Warren, Terri; Casper, Corey; Corey, Lawrence; Wald, Anna // Journal of Infectious Diseases;1/15/2011, Vol. 203 Issue 2, p180 

    Background. Patients with newly acquired genital herpes simplex virus 2 (HSV-2) infection have virus frequently detected at the genital mucosa. Rates of genital shedding initially decrease over time after infection, but data on long-term viral shedding are lacking. Methods. For this study, 377...

  • Herpes Simplex Virus Resistant to Acyclovir. Englund, Janet A.; Zimmerman, Mark E.; Swierkosz, Ella M.; Goodman, Jesse L.; Scholl, David R.; Balfour Jr., Henry H. // Annals of Internal Medicine;3/15/90, Vol. 112 Issue 6, p416 

    Presents a study which aims to determine the sensitivity of herpes simplex virus isolates to acyclovir and the importance of resistant isolates in hospitalized patients. Description of clinical viral procedures considered in the study; Clinical characteristics of patients with herpes simplex...

  • Herpetic Pharyngitis with Mammary and Genital Herpes due to Sexual Contact. Yoshida, Masami // Acta Dermato-Venereologica;5/27/99, Vol. 79 Issue 3, p250 

    Presents a case of herpetic pharyngitis with mammary and genital herpes in a Japanese female. Presence of crusts and erosions on the right nipple; Administration of several drugs; Genetic analysis of the Herpes simplex virus.

  • ACOG Practice Bulletin on Management of Herpes in Pregnancy. Preboth, Monica // American Family Physician;01/15/2000, Vol. 61 Issue 2, p556 

    Reports on the practice bulletin developed by the Committee on Practice Bulletins of the American College of Obstetricians and Gynecologists on the management of herpes simplex virus infection in pregnancy. Clinical considerations and recommendations; Means to help physicians make decisions...

  • The hype about herpes. Day, Michael // New Scientist;12/12/98, Vol. 160 Issue 2164, p24 

    Focuses on a campaign to encourage the wider use of drugs to suppress the herpes simplex virus type 2 (HSV2). Dublin, Ireland-based Diagnology's launching of a test for HSV2; International Herpes Management Forum's involvement in the barrage of publicity about herpes; Concerns about the...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics