The Potential Role of Vaccines in the Elimination of Falciparum Malaria and the Eventual Eradication of Malaria

Plowe, Christopher V.; Alonso, Pedro; Hoffman, Stephen L.
December 2009
Journal of Infectious Diseases;12/1/2009, Vol. 200 Issue 11, p1646
Academic Journal
In this article the authors discuss the role and effectiveness of malaria vaccines in eliminating the plasmodium falciparum virus. They reflect to the malaria elimination campaign in circumscribed islands in which longest acting of antimalarial drugs last only for months while vaccines last for years. Also stressed are the two approach that prevent P. falciparum such as the development of gametocytes in humans and the blocking of parasites transmission to mosquitoes in the sexual stage.


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