The drug--drug interaction between proton pump inhibitors and clopidogrel

Lau, Wei C.
March 2009
CMAJ: Canadian Medical Association Journal;3/31/2009, Vol. 180 Issue 7, p699
Academic Journal
In this article the authors discuss the study to examine a cytochrome P450 2C19-dependent drug-drug interaction between proton pump inhibitors and clopidogrel. They mention that the study was adapted for the imbalances in covariates such as cardiovascular comorbidities and evidence-based cardiovascular medications. However, they note that the study lack of data on patient compliance with antiplatelet therapy and did not account for ethnicity.


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