TITLE

Agricultural Genomics: Commercial Applications Bring Increased Basic Research Power

AUTHOR(S)
Decker, Jared E.
PUB. DATE
November 2015
SOURCE
PLoS Genetics;11/5/2015, Vol. 11 Issue 10, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Opinion
ABSTRACT
The author comments on a study by L. Ma and colleagues on global recombination rate in Holstein cattle. Topics include the proposed methods by researchers in 1997 to predict the generic merit of organisms using dense genotype data, significance of genomic prediction, and predicted number of Holstein cattle that will be genotyped by the end of 2015. Also mentioned is the confirmation by Ma and colleagues on the increased power to detect novel genome-wide associations.
ACCESSION #
110745760

 

Related Articles

  • New genomics service.  // New Zealand Dairy Exporter;Aug2012, Vol. 88 Issue 1, p165 

    The article provides information on HFBoost, a genomic testing service being offered by Holstein Friesian New Zealand and CRV Ambreed to all Holstein Friesian NZ members.

  • Effect of prior distributions on accuracy of genomic breeding values for two dairy traits. Nicolazzi, Ezequiel L.; Negrini, Riccardo; Chamberlain, Amanda J.; Goddard, Michael E.; Marsan, Paolo Ajmone; Hayes, Ben J. // Italian Journal of Animal Science;2013, Vol. 12 Issue 4, p555 

    The ideal method to estimate direct genomic values (DGV) would calculate the conditional mean of the breeding value given the genotype of individuals at each quantitative traits locus (QTL). In this study we compare accuracies of DGV obtained using three different prior distributions of the...

  • Untangling the DNA alphabet soup. Montgomerie, Bill // New Zealand Dairy Exporter;Nov2006, Vol. 82 Issue 4, p87 

    The article focuses on the international project to sequence the bovine genome. The U.S. National Human Genome Research Institute has funding allotted for the DNA sequencing project. Fonterra and Livestock Improvement in New Zealand has conducted a Holstein-Friesian cross Jersey crossbred trial....

  • Genome-wide detection of copy number variations using high-density SNP genotyping platforms in Holsteins. Li Jiang; Jicai Jiang; Jie Yang; Xuan Liu; Jiying Wang; Haifei Wang; Xiangdong Ding; Jianfeng Liu; Qin Zhang // BMC Genomics;2013, Vol. 14 Issue 1, p1 

    Background: Copy number variations (CNVs) are widespread in the human or animal genome and are a significant source of genetic variation, which has been demonstrated to play an important role in phenotypic diversity. Advances in technology have allowed for identification of a large number of...

  • Accuracy of genomic breeding values in multi-breed dairy cattle populations. Hayes, Ben J.; Bowman, Phillip J.; Chamberlain, Amanda C.; Verbyla, Klara; Goddard, Mike E. // Genetics Selection Evolution;Nov2009, Vol. 41 Issue 10, p1 

    Background: Two key findings from genomic selection experiments are 1) the reference population used must be very large to subsequently predict accurate genomic estimated breeding values (GEBV), and 2) prediction equations derived in one breed do not predict accurate GEBV when applied to other...

  • Accuracy of imputation to whole-genome sequence data in Holstein Friesian cattle. van Binsbergen, Rianne; Bink, Marco C. A. M.; Calus, Mario P. L.; van Eeuwijk, Fred A.; Hayes, Ben J.; Hulsegge, Ina; Veerkamp, Roel F. // Genetics Selection Evolution;Jul2014, Vol. 46, p1 

    Background: The use of whole-genome sequence data can lead to higher accuracy in genome-wide association studies and genomic predictions. However, to benefit from whole-genome sequence data, a large dataset of sequenced individuals is needed. Imputation from SNP panels, such as the Illumina...

  • Identification and Dissection of Four Major QTL Affecting Milk Fat Content in the German Holstein-Friesian Population. Xiaolong Wang; Christine Wurmser; Pausch, Hubert; Simone Jung; Reinhardt, Friedrich; Tetens, Jens; Thaller, Georg; Fries, Ruedi // PLoS ONE;Jul2012, Vol. 7 Issue 7, p1 

    Milk composition traits exhibit a complex genetic architecture with a small number of major quantitative trait loci (QTL) explaining a large fraction of the genetic variation and numerous QTL with minor effects. In order to identify QTL for milk fat percentage (FP) in the German...

  • Genome-wide association and biological pathway analysis for milk-fat composition in Danish Holstein and Danish Jersey cattle. Buitenhuis, Bart; Janss, Luc L. G.; Poulsen, Nina A.; Larsen, Lotte B.; Larsen, Mette K.; Sørensen, Peter // BMC Genomics;2014, Vol. 15 Issue 1, p1548 

    Background: The milk fat profile of the Danish Holstein (DH) and Danish Jersey (DJ) show clear differences. Identification of the genomic regions, genes and biological pathways underlying the milk fat biosynthesis will improve the understanding of the biology underlying bovine milk fat...

  • Characteristics of linkage disequilibrium in North American Holsteins. Bohmanova, Jarmila; Sargolzaei, Mehdi; Schenkel, Flavio S. // BMC Genomics;2010, Vol. 11, p421 

    Background: Effectiveness of genomic selection and fine mapping is determined by the level of linkage disequilibrium (LD) across the genome. Knowledge of the range of genome-wide LD, defined as a non-random association of alleles at different loci, can provide an insight into the optimal density...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics