C.S.F. Protein in Multiple Sclerosis
Related Articles
- Review of "Proteins of the Cerebrospinal Fluid" (2nd Edition) by Edward J. Thompson. Connor, James R. // Cerebrospinal Fluid Research;2007, Vol. 4, p1
This book on cerebrospinal fluid (CSF) proteins is primarily focused on immunoglobulins. The book was written as an extension of a meeting on multiple sclerosis to provide a more extensive consideration of the CSF.
- Oligoclonal Bands and CSF Markers Associated With MS Disease Course. Baney, JacK // Neurology Reviews;Oct2011, Vol. 19 Issue 10, p11
The article focuses on the retrospective analysis by researchers Pedro Lourenco and colleagues regarding the association of cerebrospinal fluid (CSF) protein markers/oligoclonal bands (OCB) in the disease course and progression in multiple sclerosis patients (MS).
- CSF 14-3-3 protein assay and MRI as prognostic markers in patients with a clinically isolated syndrome suggestive of MS. Martínez-Yélamos, A.; Rovira, A.; Sánchez-Valle, R.; Martínez-Yélamos, S.; Tintoré, M.; Blanco, Y.; Graus, F.; Montalban, X.; Arbizu, T.; Saiz, A. // Journal of Neurology;Oct2004, Vol. 251 Issue 10, p1278
Presents a letter to the editor about the use CSF 14-3-3 protein assay and magnetic resonance imaging as prognostic markers in patients with a clinically isolated syndrome suggestive of multiple sclerosis.
- Cerebrospinal fluid neurofilament: the biomarker that will resuscitate the 'Spinal Tap'. Giovannoni, Gavin // Multiple Sclerosis (13524585);Mar2010, Vol. 16 Issue 3, p285
In this article, the author discusses the role of cerebrospinal fluid (CSF) which serves as biochemical markers in multiple sclerosis. He cites that neurofilament (NF) protein is a potential surrogate for recognizing axonal damage. Moreover, he emphasizes that axonal injury triggers the release...
- CXCL13 is a biomarker of inflammation in multiple sclerosis, neuromyelitis optica, and other neurological conditions. Alvarez, Enrique; Piccio, Laura; Mikesell, Robert J; Klawiter, Eric C; Parks, Becky J; Naismith, Robert T; Cross, Anne H // Multiple Sclerosis Journal;Aug2013, Vol. 19 Issue 9, p1204
CXCL13, a B-cell chemokine, has been proposed as a biomarker in a variety of conditions, some of which can mimic multiple sclerosis and can have very high levels. In this case-control study, cerebrospinal fluid (CSF) CXCL13 was elevated in multiple sclerosis, neuromyelitis optica and other...
- Improved resolution of human cerebrospinal fluid proteins on two-dimensional gels. Hammack, BN; Owens, GP; Burgoon, MP; Gilden, DH // Multiple Sclerosis (13524585);Oct2003, Vol. 9 Issue 5, p472
Proteomics combines two-dimensional gel electrophoresis and peptide mass fingerprinting and can potentially identify a protein(s) unique to disease. Such proteins can be used either for diagnosis or may be relevant to the pathogenesis of disease. Because patients with multiple sclerosis (MS)...
- Cerebrospinal fluid — physiology, analysis and interpretation of protein patterns for diagnosis of neurological diseases. Reiber, H. // Multiple Sclerosis (13524585);Jun98, Vol. 4 Issue 3, p99
The state of the art in routine CSF analysis is reviewed with particular reference to multiple sclerosis regarding: (1) The physiology and pathophysiology of blood-CSF barrier function and dysfunction with the CSF flow rate as main modulator of blood- and brain-derived protein concentrations in...
- Oligoclonal bands and cerebrospinal fluid markers in multiple sclerosis: associations with disease course and progression. Lourenco, Pedro; Shirani, Afsaneh; Saeedi, Jameelah; Oger, Joel; Schreiber, William E; Tremlett, Helen // Multiple Sclerosis Journal;Apr2013, Vol. 19 Issue 5, p577
The article presents the study which examines the role of oligoclonal bands (OCBs) in disease course and progression. It states that the cerebrospinal fluid (CSF) data for 1120 patients with multiple sclerosis (MS) were studied for link between OCBs and CSF parameters and clinical data,...
- Rituximab levels in cerebrospinal fluid of patients with neurological autoimmune disorders. Petereit, H. F.; Rubbert-Roth, A. // Multiple Sclerosis (13524585);Feb2009, Vol. 15 Issue 2, p189
Background Rituximab, a monoclonal antibody against the B-cell-specific surface protein CD20, is being evaluated for treatment of multiple sclerosis and neuromyelitis optica. Both diseases are restricted to the brain and cerebrospinal fluid (CSF). Whereas the ability of rituximab to deplete B...
- Detection of protein aggregates in brain and cerebrospinal fluid derived from multiple sclerosis patients. David, Monique Antoinette; Tayebi, Mourad // Frontiers in Neurology;Dec2014, Vol. 5, p1
Studies of the properties of soluble oligomer species of amyloidogenic proteins, derived from different proteins with little sequence homology, have indicated that they share a common structure and may share similar pathogenic mechanisms. Amyloid b, tau protein, as well as amyloid precursor...
