Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy

Sookoian, Silvia; Castaño, Gustavo; Pirola, Carlos J.; Shaffer, Eldon; Kupcinskas, Limas
April 2008
World Journal of Gastroenterology;4/7/2008, Vol. 14 Issue 13, p2126
Academic Journal
The pathogenesis of intrahepatic cholestasis of pregnancy (ICP), a disorder that adversely affects maternal wellbeing and fetal outcome, is unclear. However, multiple factors probably interact along with a genetic predisposition. We would like to add some comments on a paper recently published concerning the role of ABCB11 and ABCC2 polymorphisms in both ICP and contraceptive-induced cholestasis, especially in the light of our recently published findings about a positive association between ICP and ABCC2 common variants.


Related Articles

  • Cholestatic Jaundice Due to Derivatives of Oxacillin. Deboever, G. // American Journal of Gastroenterology;May1987, Vol. 82 Issue 5, p483 

    Presents a letter to the editor in response to two articles about a case report of cholestatic jaundice after oral cloxacillin treatment in the 1986 issue.

  • Prophylaxis of Postoperative Biliary Stasis. Math, Mahantayya V. // American Journal of Gastroenterology;Sep1988, Vol. 83 Issue 9, p1005 

    Presents a letter to the editor in response to the article "Prophylaxis of Postoperative Biliary Stasis: A Retrospective and Prospective Study," by S. Nobusawa and M. Endo, in the 1988 issue.

  • CEFTRIAXONE INDUCED CHOLESTASIS IN A NEONATE: A CASE REPORT. Ravisha, M. S.; Godambe, S. V. // Indian Journal of Medical Sciences;Feb2004, Vol. 58 Issue 2, p73 

    Presents a letter to the editor regarding a case report on ceftriaxone induced cholestasis in a neonate.

  • Extrahepatic Cholestasis Attributable to Tuberculous Adenitis. Arrese, Marco; Lopez, Francisco; Rossi, Ricardo; Traipe, Elfrides; Cruz, Francisco // American Journal of Gastroenterology;May1997, Vol. 92 Issue 5, p912 

    Presents a letter to the editor about the extrahepatic cholestasis which is attributable to tuberculous adenitis.

  • Cholestasis, Hypoprothrombinemia, and Cefotaxime, or How to Prolong a Short Story. Danan, G.; Erlinger, S. // American Journal of Gastroenterology;Aug1991, Vol. 86 Issue 8, p1094 

    Presents a letter to the editor about the role of cholestasis in the occurrence of hypoprothrombinemia in a patient with jaundice treated with cefotaxime.

  • Intrahepatic Cholestasis Due to Ticarcillin--Clavulanate. Sweet, Jon M.; Jones, Michael P. // American Journal of Gastroenterology;Apr1995, Vol. 90 Issue 4, p675 

    Presents a letter to the editor about the case of intrahepatic cholestasis due to ticarcillin-clavulanate.

  • Pruritus in Diseases with Cholestasis: Pruritogen and Serum Bile Acids. Math, Mahantayya V.; Ghent, C. N. // American Journal of Gastroenterology;Sep1987, Vol. 82 Issue 9, p915 

    Presents a letter to the editor in response to the article "Pruritus of Cholestasis Is Related to Effects of Bile Salts on the Liver, Not the Skin," by C. N. Ghent, which appeared in a 1987 issue.

  • Cloxacillin-Induced Cholestasis in a Renal Allograft Patient with Chronic Hepatitis. Pascual, J.; Orofino, L.; Marcén, R.; Quereda, C.; Ortuño, J. // American Journal of Gastroenterology;Mar1990, Vol. 85 Issue 3, p335 

    Presents a letter to the editor about cloxacillin-induced cholestasis in a renal allograft patient with chronic hepatitis.

  • Hypoprothrombinemia and Cefotaxime. Danan, G.; Erlinger, S. // American Journal of Gastroenterology;Jun1990, Vol. 85 Issue 6, p763 

    Presents a letter to the editor about a case of hypoprothrombinemia in a patient with cholestasis due to acute pancreatitis and treated with cefotaxime.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics