Risk of duodenal cancer in patients with familial adenomatous polyposis

Biasco, G.; Pantaleo, M. A.; di Febo, G.; Calabrese, C.; Brandi, G.
October 2004
Gut;Oct2004, Vol. 53 Issue 10, p1547
Academic Journal
This article presents an analysis of the natural history of duodenal adenomas in familial adenomatous polyposis. A total of 368 patients were examined over a mean period of 7.6 years. They showed significant progression of Spigelman stage overtime. At the end of the study, the incidence stage IV was 7.0%. All of the patients have undergone a proctocolectomy with J-pouch ileoanal anastomosis. They probably leading to a smaller risk of duodenal neoplasia. A separate analysis on patients was performed and were operated.


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