Autoimmune myasthenia gravis after cardiac surgery

Scoppetta, C.; Onorati, P.; Eusebi, F.; Fini, M.; Evoli, A.; Vincent, A.
March 2003
Journal of Neurology, Neurosurgery & Psychiatry;Mar2003, Vol. 74 Issue 3, p392
Academic Journal
Autoimmune myasthenia gravis (MG) is a heterogenous disorder. In young women, the thymus gland is often hyperplastic, and the patients respond well to thymectomy. However, in the increasing number of patients over the age of 40 years, predominantly men, thymic hyperplasia is uncommon, and there are no clear aetiological clues. Authors diagnosed MG in three male patients who had undergone cardiac surgery between three and ten weeks before developing symptoms. The patients presented with ocular, bulbar, and mild generalised weakness. None of them was taking antiarrhythmic agents or other drugs impairing neuromuscular transmission and none of them had any thyroid or other autoimmune disorder.


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