Localized LECT2 amyloidosis of the adrenal gland with coexisting MGUS: a diagnostic challenge

Angell, Trevor; Swaika, Abhisek; Sood, Neha; Goldfarb, Melanie; Siddiqi, Imran; Ailawadhi, Sikander
September 2015
Annals of Hematology;Sep2015, Vol. 94 Issue 9, p1603
Academic Journal
A case study of 74-year-old woman, with a history of stage 1B uterine cancer status-post hysterectomy and radiation therapy is presented. Topics discussed include characterization of the isolated amyloid protein, confirmation of amyloid presence by Congo red staining, and role of liquid chromatographytandem mass spectrometry (LC-MS/MS) for an accurate diagnosis of LECT2-associated amyloidosis.


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