Exploration of gender differences of Chlamydia trachomatis infection amongst young people reveals limitations of using sexual histories to assess risk in high-prevalence areas

Syred, Jonathan; Engler, Birgit; Campbell, Lucy; Baraitser, Paula; Sheringham, Jessica
July 2014
International Journal of STD & AIDS;Jul2014, Vol. 25 Issue 8, p564
Academic Journal
journal article
In England, chlamydia positivity in young men occurs at a slightly older age group (20–24 years) than positivity among young women (16–20 years) but total rates of infection among the population aged under 25 years are similar. Where there is variation, explanations often focus on individual sexual risk behaviours. We aimed to explore the extent to which variations in chlamydia positivity could be explained by reasons for attendance and sexual behaviour at a sexual health clinic in a high-prevalence area of England. Data routinely collected during clinic appointments were extracted retrospectively from the medical records of 952 clinic users (634 women) aged 16 to 24. We tested for associations with chlamydia positivity using the Chi square statistic and multiple logistic regression for men and women separately; 19.5% of men tested positive (95% CI: 15.1–23.8) compared to 11.5% of women (95% CI: 9.0–14.0). Reporting a partner with symptoms or a sexually transmitted infection diagnosis was significantly associated with a positive diagnosis (Men OR: 3.14, 95% CI: 1.5–6.25; Women OR: 3.78, 95% CI: 1.83–7.83). All other reasons for attendance and all sexual behaviour variables were not significantly associated with a positive diagnosis. Differences in chlamydia positivity between men and women attending this service cannot be explained by individual sexual behaviours found to be associated with higher risk of infection in national studies. Our findings question the utility of individual behavioural data routinely collected during clinic appointments for predicting risk of sexually transmitted infections in high-prevalence areas.


Related Articles

  • Simplifying chiamydia testing: an innovative Chiamydia trachomatis testing approach using the internet and a home sampling strategy: population based study. Novak, D. P.; Karlsson, R. B. // Sexually Transmitted Infections;Apr2006, Vol. 82 Issue 2, p142 

    Objectives: To measure the coverage, gender distribution, and participants' prevalence of genital Chlamydia trachomatis infections using a new Internet based self selective testing approach by means of home sampling in the general population in Sweden. To investigate factors associated with...

  • Chlamydia's Hidden Toll. Corinna, Heather // Issues;Jun2006, Issue 75, p25 

    The article provides information about chlamydia, the most common sexually transmitted diseases (STD) in the U.S., Australia and United Kingdom. Chlamydia is a common disease on sexually active women aged 15 to 24. About 15,000 cases in young adults was reported in Australia in 2001. Women who...

  • Systematic selection of screening participants by risk score in a chlamydia screening programme is feasible and effective. Van Den Broek, Ingrid V. F.; Brouwers, Elfi E. H. G.; Götz, Hannelore M.; Van Bergen, Jan E. A. M.; De Coul, Eline L. M. Op; Fennema, Johannes S. A.; Koekenbier, Rik H.; Pars, Lydia L.; Van Ravesteijn, Sander M.; Hoebe, Christian J. P. A. // Sexually Transmitted Infections;Apr2012, Vol. 88 Issue 3, p205 

    Objectives Systematic screening for Chlamydia trachomatis by individual invitation can be optimised by filtering participants on risk profile, excluding people at no or low risk. The authors investigated this technique in a large-scale chlamydia screening programme in the Netherlands in one...

  • The Silent Epidemic of Chlamydia trachomatis: The Urgent Need for Detection and Treatment in Women. Walsh, Cathleen; Anderson, Lynda A.; Irwin, Kathleen // Journal of Women's Health & Gender-Based Medicine;May2000, Vol. 9 Issue 4, p339 

    This article focuses on medical screening for sexually transmitted Chlamydia trachomatis infection among women in the U.S. Screening women for chlamydial infection is now relatively inexpensive and, with new urine diagnostic tests, can be simple and painless. Several screening tests that use...

  • Clinic-based evaluation of Clearview Chlamydia MF for detection of Chlamydia trachomatis in vaginal and cervical specimens from women at high risk in China. Yin, Y.-P.; Peeling, R. W.; Chen, X.-S.; Gong, K.-L.; Zhou, H.; Gu, W.-M.; Zheng, H.-P.; Wang, Z.-S.; Yong, G.; Cao, W.-L.; Shi, M.-Q.; Wei, W.-H.; Dai, X.-Q.; Gao, X.; Chen, Q.; Mabey, D. // Sexually Transmitted Infections;Dec2006 Supplement V, Vol. 82, pv33 

    Objectives: To determine the performance of a rapid Chlamydia trachomatis (CT) test (Clearview Chlamydia MF) compared to the current ‘gold standard’ (Roche Amplicor CT assay) test, and to assess acceptability of the tests to patients. Methods: A total of 1497 women at sexually...

  • Condom effectiveness against non-viral sexually transmitted infections: a prospective study using electronic daily diaries. Crosby, Richard A.; Charnigo, Richard A.; Weathers, Chandra; Caliendo, Angela M.; Shrier, Lydia A. // Sexually Transmitted Infections;Nov2012, Vol. 88 Issue 7, p484 

    Objectives To prospectively evaluate the protective value of consistent and correct use of latex condoms against the acquisition of Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis. Methods Patients (N=929) attending clinics that treat sexually transmitted infections (STIs)...

  • The Role of Reinfection and Partner Notification in the Efficacy of Chlamydia Screening Programs. Heijne, Janneke C. M.; Althaus, Christian L.; Herzog, Sereina A.; Kretzschmar, Mirjam; Low, Nicola // Journal of Infectious Diseases;2/1/2011, Vol. 203 Issue 3, p372 

    Repeated Chlamydia trachomatis infections after treatment are common. One reason is reinfection from untreated partners in ongoing sexual partnerships. Mathematical models that are used to predict the impact of screening on reducing chlamydia prevalence often do not incorporate reinfection and...

  • Screening and treatment of Chlamydia trachomatis infections. Kalwij, Sebastian; Macintosh, Mary; Baraitser, Paula // BMJ: British Medical Journal (Overseas & Retired Doctors Edition;4/24/2010, Vol. 340 Issue 7752, p912 

    The article presents a clinical review of the screening and treatment of Chlamydia trachomatis infections. It discusses the diagnosis and management of chlamydia, which is the most commonly diagnosed bacterial sexually transmitted infection worldwide. It examines the serious consequences of...

  • Spending money to save money. Mehta, S.D.; Shahmanesh, M.; Zenilman, J.M. // Sexually Transmitted Infections;Feb2003, Vol. 79 Issue 1, p4 

    Editorial. Comments on an article regarding Chlamydia trachomatis screening, published in a previous issue of 'Sexually Transmitted Infections.' Cost effectiveness of screening; Need for studies to improve accuracy of morbidity assumptions; Deficiencies in the availability and strength of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics