TITLE

Fulminant liver failure in a child with invasive group A streptococcal infection

AUTHOR(S)
Biesel-Desthieux, M.-N.; Tissières, P.; Belli, D. C.; Le Coultre, C.; Gervaix, A.; Masserey Spicher, V.
PUB. DATE
April 2003
SOURCE
European Journal of Pediatrics;2003, Vol. 162 Issue 4, p245
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Unlabelled: Liver involvement is mentioned in streptococcal toxic shock syndrome, but never as fulminant liver failure (FLF). We report the case of a 2-year-old child who developed isolated FLF secondary to invasive group A streptococcal infection without shock due to a M1T1-type strain expressing speA, speB and speC toxin genes. On antibiotics, he recovered rapidly without liver transplantation.Conclusion: A streptococcal pyrogenic exotoxin likely constituted the initial insult leading to FLF. This etiology can be included in the differential diagnosis of FLF and would support early introduction of antibiotics.
ACCESSION #
9338903

 

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