Monte carlo conditional inference for log-linear and logistic models: a survey of current methodology

Caffo, B S; Booth, J G
March 2003
Statistical Methods in Medical Research;Mar2003, Vol. 12 Issue 2, p109
Academic Journal
journal article
Nuisance parameters are parameters that are not of immediate interest to the experimenter. For log-linear and logistic models the null distribution of (most) statistics of interest depends on such parameters. Traditionally, nuisance parameters were eliminated by performing inference with respect to the chi-squared limiting distribution of common test statistics. An alternative solution is to eliminate the nuisance parameters by conditioning on their minimal sufficient statistics. The support of the resulting conditional distribution is often intractable, making null probability calculations challenging. An often feasible way to avoid complete enumeration of this support is to approximate conditional probabilities using Monte Carlo methods. In this article we survey recent developments in Monte Carlo conditional analysis for log-linear and logistic models focusing on the algorithms proposed by Booth and Butler, Diaconis and Sturmfels, Smith et al., and Mehta et al. We illustrate these algorithms with simple motivating examples.


Related Articles

  • The impact of unmeasured baseline effect modification on estimates from an inverse probability of treatment weighted logistic model. Delaney, Joseph A. C.; Platt, Robert W.; Suissa, Samy // European Journal of Epidemiology;Jul2009, Vol. 24 Issue 7, p343 

    We present the results of a Monte Carlo simulation study in which we demonstrate how strong baseline interactions between a confounding variable and a treatment can create an important difference between the marginal effect of exposure on outcome (as estimated by an inverse probability of...

  • Bayesian methods for contingency tables using Gibbs sampling. Green, Paul E.; Taesung Park // Statistical Papers;Jan2004, Vol. 45 Issue 1, p33 

    Cell counts in contingency tables can be smoothed using log-linear models. Recently, sampling-based methods such as Markov chain Monte Carlo (MCMC) have been introduced, making it possible to sample from posterior distributions. The novelty of the approach presented here is that all conditional...

  • Multi-Task Learning for Classification with Dirichlet Process Priors. Ya Xue; Xuejun Liao; Carin, Lawrence; Krishnapuram, Balaji // Journal of Machine Learning Research;1/1/2007, Vol. 8 Issue 1, p35 

    Consider the problem of learning logistic-regression models for multiple classification tasks, where the training data set for each task is not drawn from the same statistical distribution. In such a multi-task learning (MTL) scenario, it is necessary to identify groups of similar tasks that...

  • Predictors of Fear of Sexual Rejection in Individuals with Multiple Sclerosis. Quinn, Helen; Flood, Sara; Mendelowitz, Elana; Marrie, Ruth; Foley, Frederick // Sexuality & Disability;Mar2015, Vol. 33 Issue 1, p53 

    Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that is often associated with a myriad of physical and cognitive impairments. Sexual dysfunction (SD) is a common yet often overlooked symptom in MS. The present study aimed to explore one type of SD, namely perceived...

  • Temporal Trends and Predictors for Cancer Clinical Trial Availability for Medically Underserved Populations. Gerber, David E.; Lakoduk, Ashley M.; Priddy, Laurin L.; Yan, Jingsheng; Xie, Xian‐Jin // Oncologist;Jun2015, Vol. 20 Issue 6, p674 

    Background. Lack of access to available cancer clinical trials has been cited as a key factor limiting trial accrual, particularly among medically underserved populations. We examined the trends and factors in clinical trial availability within a major U.S. safety-net hospital system. Materials...

  • Prevalence of Hepatitis C Virus Infection in Alcoholic Patients: Cohort Study and Systematic Review. Novo-Veleiro, Ignacio; de la Calle, Cristina; Domínguez-Quibén, Susana; Pastor, Isabel; Marcos, Miguel; Laso, Francisco-Javier // Alcohol & Alcoholism;Sep/Oct2013, Vol. 48 Issue 5, p564 

    Aims: Prevalence of chronic hepatitis C virus (HCV) infection among alcoholics is thought to be higher than in the general population, although prevalence rates reported are quite variable. Our study is aimed to analyze HCV prevalence in a cohort of alco-holics and to perform a systematic review...

  • Rates of violence in patients classified as high risk by structured risk assessment instruments. Singh, Jay P.; Fazei, Seena; Gueorguieva, Ralitza; Buchanan, Alec; Fazel, Seena // British Journal of Psychiatry;Mar2014, Vol. 204 Issue 3, p180 

    Background: Rates of violence in persons identified as high risk by structured risk assessment instruments (SRAIs) are uncertain and frequently unreported by validation studies.Aims: To analyse the variation in rates of violence in individuals identified as high risk by...

  • Variation Over Time in the Association between Polypharmacy and Mortality in the Older Population. Richardson, Kathryn; Ananou, Alexandrine; Lafortune, Louise; Brayne, Carol; Matthews, Fiona E. // Drugs & Aging;2011, Vol. 28 Issue 7, p547 

    Background: In the older population, multimorbidity is common and 'best practice' may invite the prescription of multiple medications. Objective: To examine the association between polypharmacy, defined as the concurrent use of five or more prescription or nonprescription medications, and...

  • Examining Incentive Design Strategies for Worksite Wellness Program Engagement. Norman, Gregory J.; Heltemes, Kevin J.; Drew, Joseph // Population Health Management;Dec2014, Vol. 17 Issue 6, p324 

    The objective was to examine employee engagement in worksite wellness activities at 2 large US companies that differed in engagement strategy and incentive plan. Inclusion criteria were US employees aged 18 to 65 who were eligible to receive wellness benefits throughout 2012. Company B's...


    Lucid dreams occur when a person is aware that he is dreaming while he is dreaming. In a representative sample of German adults (N = 919), 51% of the participants reported that they had experienced a lucid dream at least once. Lucid dream recall was significantly higher in women and negatively...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics