TITLE

Saddlepoint distribution function approximations in biostatistical inference

AUTHOR(S)
Kolassa, J.E.
PUB. DATE
January 2003
SOURCE
Statistical Methods in Medical Research;Jan2003, Vol. 12 Issue 1, p59
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Applications of saddlepoint approximations to distribution functions are reviewed. Calculations are provided for marginal distributions and conditional distributions. These approximations are applied to problems of testing and generating confidence intervals, particularly in canonical exponential families.
ACCESSION #
9121177

 

Related Articles

  • Biometrika Centenary: Theory and general methodology. Davison, A. C. // Biometrika;Feb2001, Vol. 88 Issue 1, p13 

    Contributions to statistical theory and general methodology published in Biometrika, 1901–2000, are telegraphically reviewed.

  • A critical cross-validation of high throughput structural binding prediction methods for pMHC. Knapp, Bernhard; Omasits, Ulrich; Frantal, Sophie; Schreiner, Wolfgang // Journal of Computer-Aided Molecular Design;May2009, Vol. 23 Issue 5, p301 

    T-cells recognize antigens via their T-cell receptors. The major histocompatibility complex (MHC) binds antigens in a specific way, transports them to the surface and presents the peptides to the TCR. Many in silico approaches have been developed to predict the binding characteristics of...

  • The concept of and search for the fair distribution in cooperative games. Smol'yakov, E. R. // Cybernetics & Systems Analysis;Nov2008, Vol. 44 Issue 6, p906 

    Well-known conflict equilibria are used to formulate the concept of fair distribution, and a technique is proposed to find it in an arbitrary cooperative game. Any cooperative game is shown to have only one fair distribution, which can always be found from the formulas of conflict equilibrium...

  • Properties of saddle points for generalized augmented Lagrangian. Qian Liu; Wan Mei Tang; Xin Min Yang // Mathematical Methods of Operations Research;2009, Vol. 69 Issue 1, p111 

    For inequality constrained optimization problem, we show the existence of local saddle point of generalized augmented Lagrangian under weak second-order sufficient conditions which are weaker than the second-order sufficient conditions in the literature. We further discuss the existence of...

  • On Approximate Representation of Periodic Motions at a Saddle Point. Martynyuk, A. A.; Nikitina, N. V. // International Applied Mechanics;Sep2002, Vol. 38 Issue 9, p1138 

    The results of a qualitative analysis of a bistable oscillator are applied to the approximate integration of a system with a closed trajectory about a saddle point.

  • Primal-dual subgradient methods for convex problems. Nesterov, Yurii // Mathematical Programming;Aug2009, Vol. 120 Issue 1, p221 

    In this paper we present a new approach for constructing subgradient schemes for different types of nonsmooth problems with convex structure. Our methods are primal-dual since they are always able to generate a feasible approximation to the optimum of an appropriately formulated dual problem....

  • Korpelevich's method for variational inequality problems in Banach spaces. Iusem, Alfredo; Nasri, Mostafa // Journal of Global Optimization;May2011, Vol. 50 Issue 1, p59 

    We propose a variant of Korpelevich's method for solving variational inequality problems with operators in Banach spaces. A full convergence analysis of the method is presented under reasonable assumptions on the problem data.

  • Communication: Prediction of the rate constant of bimolecular hydrogen exchange in the water dimer using an ab initio potential energy surface. Yimin Wang; Bowman, Joel M.; Xinchuan Huang // Journal of Chemical Physics;9/21/2010, Vol. 133 Issue 11, p111103 

    We report the properties of two novel transition states of the bimolecular hydrogen exchange reaction in the water dimer, based on an ab initio water dimer potential [A. Shank et al., J. Chem. Phys. 130, 144314 (2009)]. The realism of the two transition states is assessed by comparing...

  • The weighted log-rank class under truncated binomial design: saddlepoint p-values and confidence intervals. Abd-Elfattah, Ehab // Lifetime Data Analysis;Apr2012, Vol. 18 Issue 2, p247 

    The randomization design used to collect the data provides basis for the exact distributions of the permutation tests. The truncated binomial design is one of the commonly used designs for forcing balance in clinical trials to eliminate experimental bias. In this article, we consider the exact...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics