TITLE

Tensile strength of wound closure with cyanoacrylate glue

AUTHOR(S)
Shapiro, Andrew J.; Dinsmore, Robert C.; North Jr., James H.; Shapiro, A J; Dinsmore, R C; North, J H Jr
PUB. DATE
November 2001
SOURCE
American Surgeon;Nov2001, Vol. 67 Issue 11, p1113
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
2-Octyl cyanoacrylate tissue adhesive is increasingly being used for closure of traumatic lacerations. Data regarding the strength of incisions closed with 2-octyl cyanoacrylate are limited. We compared the strength of disruption of closure with glue with that of more conventional methods of wound closure. Segments of fresh porcine skin measuring 3.5 x 10 cm were approximated by one of four methods: 1) 2-octyl cyanoacrylate glue, 2) surgical staples, 3) 0.5 inch Steri-Strips, and 4) interrupted 4-0 poliglecaprone 25 sutures in a subcuticular fashion. Fifteen specimens were used to test each type of closure. The strength of closure was tested on an Instron 4502 tensionometer. The peak force required for disruption of the closure was recorded and the strength of the closure was compared. Staples provided the strongest closure. Skin glue proved superior to Steri-Strips but inferior to stapled closure. The difference between skin glue and suture closure was not statistically significant (P = 0.12). Patterns of failure differed between the groups. Skin glue failed because of disruption of the skin-glue interface. 2-Octyl cyanoacrylate glue provides a wound closure that is similar to closure with an interrupted subcuticular absorbable suture. This study validates the clinical use of skin glue for closure of surgical incisions. The technique should be used with caution in areas of the body that are subject to tension.
ACCESSION #
5562967

 

Related Articles

  • Blockade of Mast Cell Activation Reduces Cutaneous Scar Formation. Chen, Lin; Schrementi, Megan E.; Ranzer, Matthew J.; Wilgus, Traci A.; DiPietro, Luisa A. // PLoS ONE;Jan2014, Vol. 9 Issue 1, p1 

    Damage to the skin initiates a cascade of well-orchestrated events that ultimately leads to repair of the wound. The inflammatory response is key to wound healing both through preventing infection and stimulating proliferation and remodeling of the skin. Mast cells within the tissue are one of...

  • Chitosan-Alginate Sponge: Preparation and Application in Curcumin Delivery for Dermal Wound Healing in Rat. Mei Dai; XiuLing Zheng; Xu Xu; XiangYe Kong; XingYi Li; Gang Guo; Feng Luo; Xia Zhao; Yu Quan Wei; Zhiyong Qian // Journal of Biomedicine & Biotechnology;2009 Regular Issue, p1 

    A biodegradable sponge, composed of chitosan (CS) and sodium alginate (SA), was successfully obtained in this work. The sponge was ethereal and pliable. The chemical structure and morphology of the sponges was characterized by FTIR and SEM. The swelling ability, in vitro drug release and...

  • Using Tissue Adhesive for Wound Repair: A Practical Guide to Dermabond. Bruns, Thomas B.; Worthington, J. Mack // American Family Physician;3/1/2000, Vol. 61 Issue 5, p1383 

    Offers guidelines on using a cyanoacrylate tissue adhesive for wound repair. History and characteristics of cyanoacrylates; Technique for use in wound closure; Precautions in using the tissue.

  • Angiogenesis Is Induced and Wound Size Is Reduced by Electrical Stimulation in an Acute Wound Healing Model in Human Skin. Ud-Din, Sara; Sebastian, Anil; Giddings, Pamela; Colthurst, James; Whiteside, Sigrid; Morris, Julie; Nuccitelli, Richard; Pullar, Christine; Baguneid, Mo; Bayat, Ardeshir // PLoS ONE;Apr2015, Vol. 10 Issue 4, p1 

    Angiogenesis is critical for wound healing. Insufficient angiogenesis can result in impaired wound healing and chronic wound formation. Electrical stimulation (ES) has been shown to enhance angiogenesis. We previously showed that ES enhanced angiogenesis in acute wounds at one time point (day...

  • Healing of periodontal flaps when closed with silk sutures and N-butyl cyanoacrylate: a clinical and histological study. Kulkarni, Sudhindra; Dodwad, Vidya; Chava, Vijay // Indian Journal of Dental Research;Apr-Jun2007, Vol. 18 Issue 2, p72 

    Background: The closure of the periodontal flaps post-surgery is a necessity for attainment of a primary union between the flap margins and the establishment of a healthy dentogingival junction. N-butyl cyanoacrylate is a tissue adhesive, which can be used for the closure of the...

  • Gravitational platelet separation. Saleh, Hadi; Cox, Felicia // British Journal of Perioperative Nursing;Apr2004, Vol. 14 Issue 4, p175 

    Focuses on the functions of platelets and the benefits of gravitational platelet separation in a wide variety of clinical settings in Great Britain. Applicability of cyanoacrylates and homologous and autologous fibrin preparations to act as wound sealants; Identification of the use of...

  • SKIN REPAIR.  // Life Extension;Feb2002, Vol. 8 Issue 2, p11 

    Reports on thymosin beta 4, a small peptide, which can be used to help patients heal after surgery. How thymosin beta 4 oversees tissue repair.

  • New Strategies in Clinical Care of Skin Wound Healing. G√ľnter, C.I.; Machens, H.-G. // European Surgical Research;Aug2012, Vol. 49 Issue 1, p16 

    The prevalence of chronic wounds is closely correlated to the aging population and so-called civilizational diseases. Therefore, they are causing morbidity and mortality of millions of patients worldwide, with an unbroken upward trend. As a consequence, chronic wounds induce enormous and rapidly...

  • Novel Biodegradable Porous Scaffold Applied to Skin Regeneration. Wang, Hui-Min; Chou, Yi-Ting; Wen, Zhi-Hong; Wang, Zhao-Ren; Chen, Chun-Hong; Ho, Mei-Ling // PLoS ONE;Jun2013, Vol. 8 Issue 6, p1 

    Skin wound healing is an important lifesaving issue for massive lesions. A novel porous scaffold with collagen, hyaluronic acid and gelatin was developed for skin wound repair. The swelling ratio of this developed scaffold was assayed by water absorption capacity and showed a value of over 20 g...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics