Investigating caspases and other markers of apoptosis in ITP

Speer, Oliver; Schmugge, Markus
July 2010
Annals of Hematology;Jul2010, Vol. 89, p45
Academic Journal
journal article
The article presents information about a study which analyzes the presence of caspase and other biomarkers of apoptosis in paediatric immune thrombocytopenia (ITP). It is said that damaged or infected nucleated cells in the body are eliminated by the process of apoptosis. The results of the study show that caspase-3 is activated in 40% of the platelets in some of the patients with primary ITP. However, more clinical trials are needed to confirm the role of caspase in apoptosis.


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