TITLE

Neonatal tumours in Malaysia: a call for heightened awareness

AUTHOR(S)
Yeap, Badrul Hisham; Zahari, Zakaria
PUB. DATE
February 2010
SOURCE
Pediatric Surgery International;Feb2010, Vol. 26 Issue 2, p207
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Purpose: Neonatal neoplasms are rare tumours notorious for their atypical presentation and unpredictable behaviour. Their optimal treatment remains uncertain, a dilemma compounded by the deleterious effects of adjuvant chemo- or radiotherapy during this vulnerable period of growth. This paper examined the relatively high incidence of these tumours and its impact on paediatric surgery in Malaysia.Methods: Neonatal tumours treated at the Department of Paediatric Surgery, Kuala Lumpur Hospital over an 8-year period were retrospectively analysed. Besides data pertaining to patient demographics, distribution of tumour types and survival rates, morbidity from disease as well as treatment was emphasised in particular.Results: The 28 neonatal tumours, majority of which were sacrococcygeal teratoma, constituted 7% of all tumours treated by the unit. Surgical excision remained the mainstay of treatment. Mortality and morbidity from disease and treatment were not insignificant, at 7 and 29%, respectively.Conclusion: The outcome of neonatal tumours treated in Malaysia appeared to be influenced by indigenous factors unique to the local healthcare setting. Several solutions were expounded, chief among these are strategies of improved and earlier detection, in addition to the centralisation of expertise for this group of tumours.
ACCESSION #
47626395

 

Related Articles

  • Is aortic valve replacement with bileaflet prostheses still contraindicated in the elderly? De Feo, Marisa; Renzulli, Attilio; Vicchio, Mariano; Della Corte, Alessandro; Onorati, Francesco; Cotrufo, Maurizio; Onorati, Franesco // Gerontology;2002, Vol. 48 Issue 6, p374 

    Background: Prolonged survival in the Western world has increased the number of elderly patients referred for open-heart surgery during the last decade. Aortic valve disease is the most common heart valve disease in aged patients. Which aortic valve substitute is best employed in the elderly is...

  • Subglottic stenosis: An evaluation of an elderly treatment-seeking population. Collins, Alissa M.; Chorath, Kevin; Simpson, C. Blake // Laryngoscope;May2019, Vol. 129 Issue 5, p1155 

    Objectives/hypothesis: To evaluate the demographics, etiology, intraoperative findings, and treatment outcomes of patients with subglottic stenosis (SGS), comparing those patients aged <65 years to an elderly population aged ≥65 years.Study Design: Retrospective...

  • ICD-9 codes and surveillance for Clostridium difficile-associated disease. Dubberke, Erik R.; Reske, Kimberly A.; McDonald, L. Clifford; Fraser, Victoria J. // Emerging Infectious Diseases;Oct2006, Vol. 12 Issue 10, p1576 

    We conducted a retrospective cohort study to compare Clostridium difficile-associated disease rates determined by C. difficile-toxin assays and International Classification of Diseases, 9th Revision (ICD-9) codes. The correlation between toxin assay results and ICD-9 codes was good (K = 0.72,...

  • Variation in Mammographic Breast Density Assessments Among Radiologists in Clinical Practice: A Multicenter Observational Study. Sprague, Brian L.; Conant, Emily F.; Onega, Tracy; Garcia, Michael P.; Beaber, Elisabeth F.; Herschorn, Sally D.; Lehman, Constance D.; Tosteson, Anna N. A.; Lacson, Ronilda; Schnall, Mitchell D.; Kontos, Despina; Haas, Jennifer S.; Weaver, Donald L.; Barlow, William E.; PROSPR Consortium // Annals of Internal Medicine;10/4/2016, Vol. 165 Issue 7, p457 

    Background: About half of the United States has legislation requiring radiology facilities to disclose mammographic breast density information to women, often with language recommending discussion of supplemental screening options for women with dense breasts.Objective:...

  • The impact of venous thromboembolism on risk of death or hemorrhage in older cancer patients. Gross, Cary P.; Galusha, Deron H.; Krumholz, Harlan M. // JGIM: Journal of General Internal Medicine;Mar2007, Vol. 22 Issue 3, p321 

    Background: Among older cancer patients, there is uncertainty about the degree to which venous thromboembolism (VTE) and its treatment increase the risk of death or major hemorrhage.Objective: To determine the prevalence of VTE in a cohort of older cancer patients, as...

  • The role of serial FDG PET for assessing therapeutic response in patients with cardiac sarcoidosis. Lee, Pei-Ing; Cheng, Gang; Alavi, Abass // Journal of Nuclear Cardiology;Feb2017, Vol. 24 Issue 1, p19 

    Background: The purpose of this study was to determine the feasibility of serial quantitative 2-deoxy-2-[18F]fluoro-D-glucose (FDG) positron emission tomography (PET) to monitor the response of cardiac sarcoidosis to treatment.Methods and Results: A total of 38 PET scan...

  • Diverticular disease in CT colonography. Lefere, Philippe; Gryspeerdt, Stefaan; Baekelandt, Marc; Dewyspelaere, Jef; van Holsbeeck, B. // European Radiology;Dec2003 Supplement 4, Vol. 13, pL62 

    The aim of this study was to evaluate findings on CT colonography (CTC) in patients with diverticular disease. In a retrospective analysis of 160 consecutive patients, who underwent CTC and conventional colonoscopy (CC), patients with diverticular disease were retrieved. The CTC images were...

  • Is anti-tumor necrosis factor therapy associated with increased mortality in patients with severe sepsis caused by pneumonia? Harbarth, Stephan; Garbino, Jorge; Pittet, Didier; Pugin, Jerome; Pugin, Jérome // Journal of Infectious Diseases;5/1/2004, Vol. 189 Issue 9, p1743 

    Presents a letter to the editor on anti-tumor necrosis therapy.

  • Multiple Lymph Node Basin Drainage in Trunk Melanoma Is Not Associated with Survival of Sentinel Lymph Node-Positive Patients. Ribero, Simone; Osella abate, Simona; Pasquali, Sadro; Rossi, Carlo Riccardo; Borgognoni, Lorenzo; Piazzalunga, Dario; Solari, Nicola; Schiavon, Mauro; Brandani, Paola; ansaloni, Luca; Ponte, Erica; Silan, Francesco; Sommariva, antonio; Bellucci, Francesco; Macripò, Giuseppe; Quaglino, Pietro // Dermatology (10188665);Oct2017, Vol. 233 Issue 2/3, p205 

    Objectives: This study was aimed at investigating the prognostic role of multiple lymph node basin drainage (MLBD) in patients with positive sentinel lymph node (SLN) biopsy.Background: MLBD is frequently observed in patients with trunk melanoma undergoing SLN. The...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics