Mesenteric venous thrombosis and factors associated with mortality: a statistical analysis with five-year follow-up

Abu-Daff, S.; Abu-Daff, N.; Al-Shahed, M.
July 2009
Journal of Gastrointestinal Surgery;Jul2009, Vol. 13 Issue 7, p1245
Academic Journal
journal article
Objective: The objective was to study the factors associated with mortality in mesenteric venous thrombosis (MVT).Methods: We reviewed all cases of bowel ischemia at our institute from 1984 to 2004 and identified 31 cases of MVT and compiled data concerning their demographics, risk factors, investigations, management, surgical procedures, and outcomes. Survival was analyzed for both 30-day and 5-year periods.Results: Analysis of factors associated with mortality in our 31 case series revealed that 30-day mortality was strongly associated with colonic involvement in ischemia (p = .008) as well as short bowel syndrome (p = .028) and possibly failure to anti-coagulate the patient (p = .07). While 5-year mortality was strongly associated with "short bowel syndrome" as defined by small bowel remaining less than 100 cm (p = .031). Further study using a multivariate Cox proportional hazard analysis showed that mortality within the 30-day period was mainly related to colon ischemia with p value of .014 and an odds ratio of 17.4, while short-bowel syndrome was the predominated factor in the 5-year mortality analysis with a p value of .029 and an odds ratio of 5.Conclusion: Thirty-day mortality for MVT is strongly associated with colonic involvement as well as "short-bowel" syndrome, while anticoagulation may be protective. Five-year survival was found to be strongly associated with "short-bowel" syndrome.


Related Articles

  • Lupus disease activity and the risk of subsequent organ damage and mortality in a large lupus cohort. Lopez, Rekha; Davidson, Julie E.; Beeby, Matthew D.; Egger, Peter J.; Isenberg, David A. // Rheumatology;Mar2012, Vol. 51 Issue 3, p491 

    Objectives. To estimate the effect of SLE disease activity, observed over a 12-month period, on the risk of irreversible organ damage and mortality, adjusted for potential confounding factors.Methods. Patients were enrolled into a prospective cohort study and followed up from 1991. This study...

  • Survival Analysis of Breast Cancer Patients using Cox and Frailty Models. Faradmal, Javad; Talebi, Atefeh; Rezaianzadeh, Abbas; Mahjub, Hossein // Journal of Research in Health Sciences;Summer/Autumn2012, Vol. 12 Issue 2, p127 

    Background: Cox proportional hazard (CPH) model is the most widely used model for survival analysis. When there are unobserved/unmeasured individuals factor, then the results of the Cox proportional hazard model may not be reliable. The purpose of this study was to compare the results of CPH and...

  • The timing of surgery and mortality in elderly hip fractures. Hyuk Joong Choi; Euichung Kim; Young Jeon Shin; Bo Youl Choi; Young Ho Kim; Tae Ho Lim // Indian Journal of Orthopaedics;Nov2014, Vol. 48 Issue 6, p599 

    Background: Early surgery is recommended for elderly hip fracture patients, but some studies show no clear advantage. The benefits of early surgery may differ according to the medical environment in different countries. The purpose of this study was to identify the potential benefits of early...

  • Mortality in former Olympic athletes: retrospective cohort analysis. Zwiers, R.; Zantvoord, F. W. A.; Engelaer, F. M.; Van Bodegom, D; Van Der Ouderaa, F. J. G.; Westendorp, R. G. J. // BMJ: British Medical Journal;12/22/2012, Vol. 345 Issue 7888, p19 

    The article presents two case studies as a retrospective cohort analysis. One is to assess the mortality risk in former Olympic athletes. Author found that increased mortality was seen among athletes from disciplines with a high risk of bodily collision and with high levels of physical contact...

  • Variation Over Time in the Association between Polypharmacy and Mortality in the Older Population. Richardson, Kathryn; Ananou, Alexandrine; Lafortune, Louise; Brayne, Carol; Matthews, Fiona E. // Drugs & Aging;2011, Vol. 28 Issue 7, p547 

    Background: In the older population, multimorbidity is common and 'best practice' may invite the prescription of multiple medications. Objective: To examine the association between polypharmacy, defined as the concurrent use of five or more prescription or nonprescription medications, and...

  • Is complying with the recommendations of sodium intake beneficial for health in individuals at high cardiovascular risk? Findings from the PREDIMED study. Merino, Jordi; Guasch-Ferré, Marta; Martínez-González, Miguel A.; Corella, Dolores; Estruch, Ramon; Fitó, Montserrat; Rós, Emilio; Aros, Fernando; Bulló, Mònica; Gómez-Gracia, Enrique; Moñino, Manuel; Lapetra, José; Serra-Majem, Lluís; Razquin, Cristina; Cosiales, Pilar Buil; Sorlí, José V.; Muñoz, Miguel A.; Pintó, Xavier; Masana, Luis; Salas-Salvadó, Jordi // American Journal of Clinical Nutrition;Mar2015, Vol. 101 Issue 3, p440 

    Background: Excess sodium intake is associated with high blood pressure, a major risk factor for cardiovascular disease (CVD). It is unknown whether decreasing sodium intake to <2300 mg/d has an effect on CVD or all-cause mortality. Objective: The objective was to assess whether reductions in...

  • Dietary phosphatidylcholine and risk of all-cause and cardiovascular-specific mortality among US women and men. Yan Zheng; Yanping Li; Rimm, Eric B.; Hu, Frank B.; Albert, Christine M.; Rexrode, Kathryn M.; Manson, JoAnn E.; Lu Qi // American Journal of Clinical Nutrition;7/1/2016, Vol. 104 Issue 1, p173 

    Background: The trimethylamine-containing nutrient phosphatidylcholine is the major dietary source for the gut microbiota metabolite trimethylamine-N-oxide (TMAO), which has been related to cardiovascular diseases (CVDs) and mortality. Previous research suggested that the relation of TMAO with...

  • National Trends in Admission for Aspiration Pneumonia in the United States, 2002-2012. Chao-Ping Wu; Yu-wei Chen; Min-Jung Wang; Pinelis, Evgeny; Wu, Chao-Ping; Chen, Yu-Wei; Wang, Min-Jung // Annals of the American Thoracic Society;Jun2017, Vol. 14 Issue 6, p874 

    Rationale: Aspiration pneumonia is a subset of pneumonias prevalent in elderly patients and patients with neurologic disorders. Researchers in previous studies mostly reported incidence and/or mortality rates based on regional data or in specific subgroups of patients. There is a...

  • Anterior and Anterolateral Approaches for THA Are Associated With Lower Dislocation Risk Without Higher Revision Risk. Sheth, Dhiren; Cafri, Guy; Inacio, Maria; Paxton, Elizabeth; Namba, Robert; Inacio, Maria C S; Paxton, Elizabeth W; Namba, Robert S // Clinical Orthopaedics & Related Research;Nov2015, Vol. 473 Issue 11, p3401 

    Background: Lack of consensus continues regarding the benefit of anteriorly based surgical approaches for primary total hip arthroplasty (THA). The purpose of this study was to evaluate the risk of aseptic revision, septic revision, and dislocations for various approaches used in...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics