Circadian rhythms of water and electrolyte excretion in manic-depressive psychosis

Moody, J. P.; Allsopp, M. N. E.; Allsopp, M N
August 1969
British Journal of Psychiatry;Aug69, Vol. 115 Issue 525, p923
Academic Journal
journal article
The article presents a study that examines the circadian rhythms of water, electrolytes and creatinine excretion in manic depressive psychosis. Subjects of the study were twelve female patients aged 30 to 61 suffering from severe manic-depressive illness. They were examined during the depressive phase of their illness and after their recovery. Their mood, psychomotor retardation and verbal output were rated daily. Their urine samples were also collected in an eight hour interval throughout the investigation for analysis. The findings showed changes in the circadian rhythm; however, no fixed pattern of alteration was found in it. The study also found that potassium and chloride rhythms were statistically related.


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