TITLE

Molecular regulation of HDL metabolism and function: implications for novel therapies

AUTHOR(S)
Rader, Daniel J.
PUB. DATE
December 2006
SOURCE
Journal of Clinical Investigation;Dec2006, Vol. 116 Issue 12, p3090
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
HDL metabolism represents a major target for the development of therapies intended to reduce the risk of atherosclerotic cardiovascular disease. HDL metabolism is complex and involves dissociation of HDL apolipoprotein and HDL cholesterol metabolism. Advances in our understanding of the molecular regulation of HDL metabolism, macrophage cholesterol efflux, and HDL function will lead to a variety of novel therapeutics.
ACCESSION #
23700430

 

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