Joint spatial analysis of gastrointestinal infectious diseases

Held, Leonhard; Graziano, Giusi; Frank, Christina; Rue, Håvard; Rue, Håvard
October 2006
Statistical Methods in Medical Research;Oct2006, Vol. 15 Issue 5, p465
Academic Journal
journal article
A major obstacle in the spatial analysis of infectious disease surveillance data is the problem of under-reporting. This article investigates the possibility of inferring reporting rates through joint statistical modelling of several infectious diseases with different aetiologies. Once variation in under-reporting can be estimated, geographic risk patterns for infections associated with specific food vehicles may be discerned. We adopt the shared component model, proposed by Knorr-Held and Best for two chronic diseases and further extended by (Held L, Natario I, Fenton S, Rue H, Becker N. Towards joint disease mapping. Statistical Methods in Medical Research 2005b; 14: 61-82) for more than two chronic diseases to the infectious disease setting. Our goal is to estimate a shared component, common to all diseases, which may be interpreted as representing the spatial variation in reporting rates. Additional components are introduced to describe the real spatial variation of the different diseases. Of course, this interpretation is only allowed under specific assumptions, in particular, the geographical variation in under-reporting should be similar for the diseases considered. In addition, it is vital that the data do not contain large local outbreaks, so adjustment based on a time series method recently proposed by (Held L, Höhle M, Hofmann M. A statistical framework for the analysis of multivariate infectious disease surveillance data. Statistical Modelling 2005a; 5: 187-99) is made at a preliminary stage. We will illustrate our approach through the analysis of gastrointestinal diseases notification data obtained from the German infectious disease surveillance system, administered by the Robert Koch Institute in Berlin.


Related Articles

  • Causal Inference Regarding Infectious Aetiology of Chronic Conditions: A Systematic Review. Orrskog, Sofia; Medin, Emma; Tsolova, Svetla; Semenza, Jan C. // PLoS ONE;Jul2013, Vol. 8 Issue 7, p1 

    Background: The global burden of disease has shifted from communicable diseases in children to chronic diseases in adults. This epidemiologic shift varies greatly by region, but in Europe, chronic conditions account for 86% of all deaths, 77% of the disease burden, and up to 80% of health care...

  • NON-ULCER DYSPEPSIA: SEEING THROUGH THE HAZE? DeVault, Kenneth R.; Johnson, David A.; Cattau Jr., Edward L. // American Journal of Gastroenterology;Dec1993, Vol. 88 Issue 12, p2125 

    Discusses research being done on the etiology of dyspepsia. Reference to a study by A. G. Klauser and colleagues, published in a 1993 issue of "Digestive Diseases Science" journal; Methods used to evaluate the condition in patients; Factors which represent the end-point of the study.

  • Geographic Isolation: Its Value in Epidemiologic Research. LOSEE, F. L. // Journal of Dental Research;Jan1963, Vol. 42 Issue 1, p202 

    The article discusses the value of geographic isolation in epidemiologic research. The author states that the geographic distribution of disease reveals variations that can provide insight into the etiology of many diseases. The value of New Zealand as a natural laboratory for nutritional...

  • A clinical study of Devadarvyadi-Vati on grahanidosha in children. Patel, Rutu V.; Kori, V. K.; Patel, K. S. // AYU: An International Quarterly Journal of Research in Ayurveda;Apr-Jun2011, Vol. 32 Issue 2, p187 

    Childhood period is considered as the period of rapid growth and development, as it is the crucial stage of establishing future. Gastro-intestinal disorders show high prevalence in pediatric practice. These conditions generally produce chronic illness. Grahanidosha is a disease related with...

  • Distribution of Giardia duodenalis Assemblages A and B among Children Living in a Remote Indigenous Community of the Northern Territory, Australia. Asher, Amy J.; Holt, Deborah C.; Andrews, Ross M.; Power, Michelle L. // PLoS ONE;Nov2014, Vol. 9 Issue 11, p1 

    Giardiasis is a communicable gastrointestinal disease caused by Giardia duodenalis and two genetic assemblages, A and B, cause human infection. In remote Indigenous communities of Australia, giardiasis is highly prevalent among children but disease transmission is poorly understood. This study...

  • Recommendations for the management of cough in adults. Morice, A. H.; McGarvey, L.; Pavord, I. // Thorax;Sep2006 Supplement, Vol. 61, pi1 

    The article discusses the guidelines given by the British Thoracic Society involving management of coughs in adults including chronic cough and acute cough in adults. It offers information about the literature of the different types of cough in adult, its epidemiology, pathopysiology, clinical...

  • Factors influencing compliance to treatment among people with chronic illness in an urban area of south india. Raghuram, Venugopal; Narasimha, Murthy N. S.; Gopinath, D. // International Journal of Biological & Medical Research;May2012, Vol. 3 Issue 3, p1495 

    Introduction -From being predominant as the leading causes of morbidity and mortality communicable diseases are now being replaced by chronic non-communicable diseases as the major causes of public health concern. By the year 2020, 80% of the disease burden in the developing countries of the...

  • Speaker's corner. Auckland, M.; Choi, B. C. K.; Puska, P. // Journal of Epidemiology & Community Health;Nov2003, Vol. 57 Issue 11, p838 

    Epidemics of communicable diseases follow predictable patterns, spreading across vulnerable population sectors by disease carrying agents or vectors. But recently many people have challenged the use of the term non-communicable and said that these diseases are actually also communicable. Chronic...

  • Infection transmission and chronic disease models in the study of infection-associated cancers. Baussano, I; Franceschi, S; Plummer, M // British Journal of Cancer;1/7/2014, Vol. 110 Issue 1, p7 

    In the last three decades, the appreciation of the role of infections in cancer aetiology has greatly expanded. Among the 13 million new cancer cases that occurred worldwide in 2008, around 2 million (16%) were attributable to infections. Concurrently, the approach to prevention of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics