Low-dose CT colonography in children: initial experience, technical feasibility, and utility

Anupindi, Sudha; Perumpillichira, James; Israel, Esther; Zalis, Michael; Jaramillo, Diego; Zalis, Michael E; Israel, Esther J
May 2005
Pediatric Radiology;May2005, Vol. 35 Issue 5, p518
Academic Journal
journal article
Background: CT colonography (CTC) is utilized as a diagnostic tool in the detection of colon polyps and early colorectal cancer in adults. Large studies in the literature, although focused on adult populations, have shown CTC to be a safe, accurate, non-invasive technique.Objective: We evaluated the technical feasibility of CTC in children using a low-dose technique.Materials and Methods: From November 2001 to April 2004 we evaluated eight patients (3-17 years) with non-contrast CTC. Seven of the patients had CTC, followed by standard colonoscopy (SC) the same day; in one patient, CTC followed a failed SC. CTC results were compared to results of SC. The estimated effective dose from each CTC was calculated and compared to that of standard barium enema.Results: CTC results were consistent with those of SC. Sensitivity for polyps 5-10 mm was 100%, and sensitivity for polyps 10 mm and larger was 66.7%. The estimated mean effective dose was 2.17 mSv for CTC, compared to the 5-6 mSv for a standard air-contrast barium enema in a small child.Conclusion: Our initial experience shows CTC in children is well-tolerated, safe, and useful. The procedure can be performed successfully with a low radiation dose, and preliminary results compare well with SC.


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