TITLE

Extra-osseous involvement of Langerhans' cell histiocytosis in children

AUTHOR(S)
Schmidt, Sabine; Eich, Georg; Hanquinet, Sylviane; Tschäppeler, Heinz; Waibel, Peter; Gudinchet, François; Tschäppeler, Heinz; Gudinchet, François
PUB. DATE
April 2004
SOURCE
Pediatric Radiology;Apr2004, Vol. 34 Issue 4, p313
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
The predominant clinical and radiological features of Langerhans' cell histiocytosis (LCH) in children are due to osseous involvement. Extra-osseous disease is far less common, occurring in association with bone disease or in isolation; nearly all anatomical sites may be affected and in very various combinations. The following article is based on a multicentre review of 31 children with extra-osseous LCH. The objective is to summarise the diverse possibilities of organ involvement. The radiological manifestations using different imaging modalities are rarely pathognomonic on their own. Nevertheless, familiarity with the imaging findings, especially in children with systemic disease, may be essential for early diagnosis.
ACCESSION #
16718089

 

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