Procalcitonin as a marker of the systemic inflammatory response to infection

Reinhart, K.; Karzai, W.; Meisner, M.
September 2000
Intensive Care Medicine;Sep2000, Vol. 26 Issue 9, p1193
Academic Journal
journal article
Examines the use of procalcitonin as a possible marker of the systemic inflammatory response to infection. Biology of procalcitonin; Relation between the increase in procalcitonin levels and severity of inflammatory response to infection; Usability of procalcitonin in identifying an infectious cause or infectious complications in patients with a systemic inflammatory response syndrome.


Related Articles

  • Procalcitonin: a valuable indicator of infection in a medical ICU? Suprin, E.; Camus, C.; Gacouin, A.; Le Tulzo, Y.; Lavoue, S.; Feuillu, A.; Thomas, R. // Intensive Care Medicine;Sep2000, Vol. 26 Issue 9, p1232 

    Objective: To assess the use of procalcitonin (PCT) for the diagnosis of infection in a medical ICU.Design: Prospective, observational study.Patients: Seventy-seven infected patients and 24 patients with systemic inflammatory response syndrome (SIRS) due to...

  • The diagnostic value of soluble urokinase plasminogen activator receptor (suPAR) compared to C-reactive protein (CRP) and procalcitonin (PCT) in children with systemic inflammatory response syndrome (SIRS). Şirinoğlu, Melis; Soysal, Ahmet; Karaaslan, Ayşe; Kepenekli Kadayifci, Eda; Yalındağ-Öztürk, Nilüfer; Cinel, İsmail; Yaman, Ali; Haklar, Goncagül; Şirikci, Önder; Turan, Serap; Altınkanat Gelmez, Gülşen; Söyletir, Güner; Bakır, Mustafa // Journal of Infection & Chemotherapy (Elsevier Inc.);Jan2017, Vol. 23 Issue 1, p17 

    Background The aim of the present study was to determine the diagnostic and prognostic values of suPAR and to compare them to CRP and PCT in pediatric patients with systemic inflammatory response syndrome (SIRS). Material-methods A prospective case-control study was performed.The study was...

  • C-Reactive Protein and Hemogram Parameters for the Non-Sepsis Systemic Inflammatory Response Syndrome and Sepsis: What Do They Mean? Gucyetmez, Bulent; Atalan, Hakan K. // PLoS ONE;2/10/2016, Vol. 11 Issue 2, p1 

    Objectives: Sepsis is one of the most common reasons of increased mortality and morbidity in the intensive care unit. The changes in CRP levels and hemogram parameters and their combinations may help to distinguish sepsis from non-sepsis SIRS. The aim of this study is to investigate the CRP and...

  • Serum procalcitonin monitoring for differential diagnosis of ventriculitis in adult intensive care patients. Martínez, R.; Gaul, C.; Buchfelder, M.; Erbguth, F.; Tschaikowsky, K.; Martínez, R // Intensive Care Medicine;Feb2002, Vol. 28 Issue 2, p208 

    The objective of our study was to assess the value of serum procalcitonin (PCT) monitoring in the differential diagnosis of ventriculitis in adult intensive care (ICU) patients. We analyzed 15 consecutive patients with ventriculitis in which a ventricular catheter had been inserted and...

  • Endotoxin immunity and the development of the systemic inflammatory response syndrome in critically ill children. Stephens, R. C. M.; Fidler, K.; Wilson, P.; Barclay, G. R.; Mythen, M. G.; Dixon, G. L. J.; Turner, M. W.; Klein, N. J.; Peters, M. J. // Intensive Care Medicine;Feb2006, Vol. 32 Issue 2, p286 

    Background: The systemic inflammatory response syndrome (SIRS) may be triggered by endotoxin. Humans have antibodies directed against the core of endotoxin (endotoxin core antibodies, EndoCAb) that appear to be protective following surgery and in sepsis. We hypothesised that...

  • Sepsis ve Septik Åžok Patojenezinde Endotelin-1'in Rolü ve Tedavide Yeni Yaklaşımlar. Güden, Demet Sinem; Temiz, Meryem; Tunçtan, Bahar; Fırat, Seyhan Şahan // Journal of Marmara University Institute of Health Sciences;2015, Vol. 5 Issue 3, p178 

    No abstract available.

  • Clinical application of sepsis biomarkers. Sankar, Vinoth; Webster, Nigel // Journal of Anesthesia;2013, Vol. 27 Issue 2, p269 

    Sepsis is one of the leading causes of death in the critically ill. Early diagnosis is important to avoid delay in instituting appropriate treatment. However, diagnosis can be delayed because of difficulty in interpreting clinical features. Sepsis biomarkers can aid early diagnosis. This article...

  • Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care. Llewelyn, Martin J.; Berger, Mario; Gregory, Mark; Ramaiah, Ravi; Taylor, Amanda L.; Curdt, Ingo; Lajaunias, Frédéric; Graf, Rolf; Blincko, Stuart J.; Drage, Stephen; Cohen, Jonathan // Critical Care;2013, Vol. 17 Issue 2, Special section p2 

    Introduction: Although many sepsis biomarkers have shown promise in selected patient groups, only C-reactive protein and procalcitonin (PCT) have entered clinical practice. The aim of this study was to evaluate three promising novel sepsis biomarkers in unselected patients at admission to...

  • Bactericidal/permeability-increasing protein (BPI) in sepsis correlates with the severity of sepsis and the outcome. Rintala, Esa; Peuravuori, Heikki; Pulkki, Kari; Voipio-Pulkki, Liisa-Maria; Nevalainen, Timo; Rintala, E; Peuravuori, H; Pulkki, K; Voipio-Pulkki, L M; Nevalainen, T // Intensive Care Medicine;Sep2000, Vol. 26 Issue 9, p1248 

    Objective: To compare the prognostic significance of bactericidal/permeability-increasing protein (BPI), group II phospholipase A2 (PLA2-II), C-reactive protein (CRP), tumour necrosis factor-alpha (TNF), interleukin-8 (IL-8) and interferon-gamma (IFN) in terms of predicting severity...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics