TITLE

Speckle tracking analysis allows sensitive detection of stress cardiomyopathy in severe aneurysmal subarachnoid hemorrhage patients

AUTHOR(S)
Cinotti, Raphaël; Piriou, Nicolas; Launey, Yoann; Tourneau, Thierry; Lamer, Maxime; Delater, Adrien; Trochu, Jean-Noël; Brisard, Laurent; Lakhal, Karim; Bourcier, Romain; Desal, Hubert; Seguin, Philippe; Mallédant, Yannick; Blanloeil, Yvonnick; Feuillet, Fanny; Asehnoune, Karim; Rozec, Bertrand; Cinotti, Raphaël; Le Tourneau, Thierry; Trochu, Jean-Noël
PUB. DATE
February 2016
SOURCE
Intensive Care Medicine;Feb2016, Vol. 42 Issue 2, p173
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Purpose: Stress cardiomyopathy is a common life-threatening complication after aneurysmal subarachnoid hemorrhage (SAH). We hypothesized that left ventricular (LV) longitudinal strain alterations assessed with speckle tracking could identify early systolic function impairment.Methods: This was an observational single-center prospective pilot controlled study conducted in a neuro-intensive care unit. Forty-six patients with severe SAH with a World Federation of Neurological Surgeons grade (WFNS) ≥ III were included. Transthoracic echocardiography (TTE) was performed on day 1, day 3, and day 7 after the patient's admission. A cardiologist blinded to the patient's management analyzed the LV global longitudinal strain (GLS). The control group comprised normal subjects matched according to gender and age.Results: On day 1 median (25th-75th percentile) GLS was clearly impaired in SAH patients compared to controls [-16.7 (-18.7/-13.7) % versus -20 (-22/-19) %, p < 0.0001], whereas LVEF was preserved [65 (59-70) %]. GLS was severely impaired in patients with a WFNS score of V versus III-IV [-15.6 (-16.9/-12.3) % versus -17.8 (-20.6/-15.8) %, p = 0.008]. Seventeen (37 %) patients had a severe GLS alteration (>- 16 %). In these patients, GLS improved from day 1 [-12.4 (-14.8/-10.9) %] to last evaluation [-16.2 (-19/-14.6) %, p = 0.0007] in agreement with the natural evolution of stress cardiomyopathy.Conclusions: On the basis of LV GLS assessment, we demonstrated for the first time that myocardial alteration compatible with a stress cardiomyopathy is detectable in up to 37 % of patients with severe SAH while LVEF is preserved. GLS could be used for sensitive detection of stress cardiomyopathy. This is critical because cardiac impairment remains a major cause of morbidity and mortality after SAH.
ACCESSION #
112462852

 

Related Articles

  • Pituitary deficiency following aneurysmal subarachnoid haemorrhage. Kreitschmann-Andermahr I; Hoff C; Niggemeier S; Pruemper S; Bruegmann M; Kunz D; Matern S; Gilsbach J M; Kreitschmann-Andermahr, I; Hoff, C; Niggemeier, S; Pruemper, S; Bruegmann, M; Kunz, D; Matern, S; Gilsbach, J M // Journal of Neurology, Neurosurgery & Psychiatry;Aug2003, Vol. 74 Issue 8, p1133 

    Objective: To investigate the incidence and severity of pituitary insufficiency after aneurysmal subarachnoid haemorrhage.Methods: Pituitary function was tested in a series of patients more than 12 months but less than 60 months after aneurysmal subarachnoid haemorrhage...

  • Takotsubo cardiomyopathy, a two-stage recovery of left ventricular systolic and diastolic function as determined by cardiac magnetic resonance imaging. Ahtarovski, Kiril Aleksov; Iversen, Kasper Karmark; Christensen, Thomas Emil; Andersson, Hedvig; Grande, Peer; Holmvang, Lene; Bang, Lia; Hasbak, Philip; Lønborg, Jacob Thomsen; Madsen, Per Lav; Engstrøm, Thomas; Vejlstrup, Niels Grove // European Heart Journal - Cardiovascular Imaging;Aug2014, Vol. 15 Issue 8, p855 

    Aims Takotsubo cardiomyopathy (TTC) is an entity mimicking acute myocardial infarction, characterized by transient severe systolic heart failure. Echocardiographic studies suggest that diastolic dysfunction is present in TTC at presentation; however, no reports exist regarding the time course of...

  • Multiple Foci of Infarction Secondary to Giant Left Ventricular Thrombus in a Patient with Takotsubo Cardiomyopathy. Celik, Murat; Yalcinkaya, Emre; Yuksel, Uygar Cagdas; Celik, Turgay; Iyisoy, Atila // Oman Medical Journal;Jul2013, Vol. 28 Issue 4, p294 

    A letter to the editor is presented in response to the article "Hemorrhagic Cardioembolic Stroke Secondary to a Left Ventricular Thrombus: A Therapeutic Dilemma" by K. Al-Farsi et al. in the January 2013 issue.

  • Longitudinal assessment of bone marrow edema-like lesions and cartilage degeneration in osteoarthritis using 3 T MR T1rho quantification. Zhao, Jian; Li, Xiaojuan; Bolbos, Radu I; Link, Thomas M; Majumdar, Sharmila // Skeletal Radiology;Jun2010, Vol. 39 Issue 6, p523 

    Objective: To quantitatively assess the relationship between bone marrow edema-like lesions (BMELs) and the associated cartilage in knee osteoarthritis (OA) using T(1rho) quantification at 3 T MRI.Materials and Methods: Twenty-four patients with knee OA and 14 control...

  • Case report of Tako-Tsubo cardiomyopathy associated with repetitive anaesthesia in a female patient with Tako-Tsubo cardiomyopathy. Hinkelbein, Jochen; Mey, Christian; Brinker, Gerrit; Pfister, Roman; Böttiger, Bernd W. // BMC Anesthesiology;2015, Vol. 15 Issue 1, p1 

    Background: Tako-Tsubo cardiomyopathy (TTC) is a rare disorder with high relevance for anaesthesia. It is an acute cardiac syndrome characterized by an acute onset of reversible left ventricular dysfunction associated with emotional and physical stress. This is the only case published of a...

  • Optimizing detection of major depression among patients with coronary artery disease using the patient health questionnaire: data from the heart and soul study. Thombs, Brett D.; Ziegelstein, Roy C.; Whooley, Mary A. // JGIM: Journal of General Internal Medicine;Dec2008, Vol. 23 Issue 12, p2014 

    Background: Clinical guidelines recommend depression screening in patients with coronary artery disease (CAD), but how to accomplish this is unclear.Objective: We evaluated the test characteristics of the two-item Patient Health Questionnaire (PHQ-2), the nine-item...

  • Gradient Spin Echo (GraSE) imaging for fast myocardial T2 mapping. Sprinkart, Alois M.; Luetkens, Julian A.; Träber, Frank; Doerner, Jonas; Gieseke, Jürgen; Schnackenburg, Bernhard; Schmitz, Georg; Thomas, Daniel; Homsi, Rami; Block, Wolfgang; Schild, Hans; Naehle, Claas P. // Journal of Cardiovascular Magnetic Resonance (BioMed Central);2015, Vol. 17 Issue 1, p1 

    Background: Quantitative Cardiovascular Magnetic Resonance (CMR) techniques have gained high interest in CMR research. Myocardial T2 mapping is thought to be helpful in diagnosis of acute myocardial conditions associated with myocardial edema. In this study we aimed to establish a technique for...

  • Day 3 versus Day 1 disseminated intravascular coagulation score among sepsis patients: a prospective observational study. Park, J. Y.; Park, S.; Park, S. Y.; Sim, Y. S.; Kim, J. H.; Hwang, Y. I.; Jang, S. H.; Jung, K. S. // Anaesthesia & Intensive Care;2016, Vol. 44 Issue 1, p57 

    The role of disseminated intravascular coagulation (DIC) has not been extensively studied in patients with sepsis. A prospective study was performed in a single university hospital. The incidences of DIC at day 1 (<24 hours post-sepsis diagnosis) and day 3 (48 to 72 hours) were investigated...

  • Lack of hemispheric dominance for consciousness in acute ischaemic stroke. Cucchiara, B.; Kasner, S.E.; Wolk, D.A.; Lyden, P.D.; Knappertz, V.A.; Ashwood, T.; Odergren, T.; Nordlund, A. // Journal of Neurology, Neurosurgery & Psychiatry;Jul2003, Vol. 74 Issue 7, p889 

    Background: Previous reports have suggested left hemispheric dominance for maintaining consciousness, although there is controversy over this claim.Objective: To compare early impairment of level of consciousness between patients with right and left hemispheric...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics